WormBase Tree Display for Gene: WBGene00015551
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| WBGene00015551 | SMap | S_parent | Sequence | C06G3 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | adah-1 | Person_evidence | WBPerson7239 | |||||
| WBPerson3965 | |||||||||
| Sequence_name | C06G3.5 | ||||||||
| Molecular_name | C06G3.5a | ||||||||
| C06G3.5a.1 | |||||||||
| CE26867 | |||||||||
| C06G3.5b | |||||||||
| CE07981 | |||||||||
| C06G3.5b.1 | |||||||||
| C06G3.5b.2 | |||||||||
| Other_name | CELE_C06G3.5 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | adah-1 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:30:56 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 02 Aug 2019 15:15:12 | WBPerson1983 | Name_change | CGC_name | adah-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | adah | ||||||||
| Allele (35) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00021662 | ||||||||
| 00021663 | |||||||||
| 00021664 | |||||||||
| 00021665 | |||||||||
| 00021666 | |||||||||
| 00021667 | |||||||||
| 00021668 | |||||||||
| 00021669 | |||||||||
| 00121423 | |||||||||
| Ortholog (43) | |||||||||
| Paralog | WBGene00016632 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | C06G3.5 is orthologous to human ADENOSINE DEAMINASE (ADA; OMIM:102700), which when mutated leads to severe combined immunodeficiency; in C. elegans, C06G3.5 is an essential gene; C06G3.5 is broadly expressed; about 2% to 6% of C06G3.5a transcripts are RNA edited to change A to G resulting in a change to residue 59 from a D to a G. | Paper_evidence | WBPaper00045975 | |||||
| WBPaper00025054 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson1823 | |||||||||
| WBPerson4025 | |||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 28 Dec 2014 00:00:00 | ||||||||
| Automated_description | Predicted to enable adenosine deaminase activity. Predicted to be involved in negative regulation of adenosine receptor signaling pathway and purine-containing compound metabolic process. Predicted to be located in cytosol and external side of plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including Legionnaires' disease; gastrointestinal system cancer (multiple); and lung disease (multiple). Is an ortholog of human ADA (adenosine deaminase). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model (22) | ||||||||
| Molecular_info | Corresponding_CDS | C06G3.5a | |||||||
| C06G3.5b | |||||||||
| Corresponding_transcript | C06G3.5a.1 | ||||||||
| C06G3.5b.1 | |||||||||
| C06G3.5b.2 | |||||||||
| Other_sequence (44) | |||||||||
| Associated_feature | WBsf646059 | ||||||||
| WBsf655028 | |||||||||
| WBsf996869 | |||||||||
| WBsf996870 | |||||||||
| WBsf1017641 | |||||||||
| WBsf228489 | |||||||||
| WBsf228490 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00010341 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00028594 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00039937 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr5192 | ||||||||
| Expr1014251 | |||||||||
| Expr1036659 | |||||||||
| Expr1144011 | |||||||||
| Expr2000543 | |||||||||
| Expr2018769 | |||||||||
| Drives_construct | WBCnstr00003971 | ||||||||
| WBCnstr00028758 | |||||||||
| Construct_product | WBCnstr00028758 | ||||||||
| Microarray_results (26) | |||||||||
| Expression_cluster (200) | |||||||||
| Interaction (179) | |||||||||
| Map_info | Map | IV | Position | 3.27757 | |||||
| Positive | Positive_clone | C06G3 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00038491 | ||||||||
| WBPaper00041771 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00062899 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
