WormBase Tree Display for Gene: WBGene00015551
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WBGene00015551 | SMap | S_parent | Sequence | C06G3 | ||
---|---|---|---|---|---|---|
Identity (6) | ||||||
Gene_info | Biotype | SO:0001217 | ||||
Gene_class | adah | |||||
Allele (35) | ||||||
RNASeq_FPKM (74) | ||||||
GO_annotation | 00021662 | |||||
00021663 | ||||||
00021664 | ||||||
00021665 | ||||||
00021666 | ||||||
00021667 | ||||||
00021668 | ||||||
00021669 | ||||||
00121423 | ||||||
Ortholog (43) | ||||||
Paralog | WBGene00016632 | Caenorhabditis elegans | From_analysis | TreeFam | ||
Panther | ||||||
WormBase-Compara | ||||||
Structured_description | Concise_description | C06G3.5 is orthologous to human ADENOSINE DEAMINASE (ADA; OMIM:102700), which when mutated leads to severe combined immunodeficiency; in C. elegans, C06G3.5 is an essential gene; C06G3.5 is broadly expressed; about 2% to 6% of C06G3.5a transcripts are RNA edited to change A to G resulting in a change to residue 59 from a D to a G. | Paper_evidence | WBPaper00045975 | ||
WBPaper00025054 | ||||||
Curator_confirmed | WBPerson1843 | |||||
WBPerson1823 | ||||||
WBPerson4025 | ||||||
WBPerson567 | ||||||
Date_last_updated | 28 Dec 2014 00:00:00 | |||||
Automated_description | Predicted to enable adenosine deaminase activity. Predicted to be involved in negative regulation of adenosine receptor signaling pathway and purine-containing compound metabolic process. Predicted to be located in cytosol and external side of plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including Legionnaires' disease; gastrointestinal system cancer (multiple); and lung disease (multiple). Is an ortholog of human ADA (adenosine deaminase). | Paper_evidence | WBPaper00065943 | |||
Curator_confirmed | WBPerson324 | |||||
WBPerson37462 | ||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | |||||
Date_last_updated | 29 Nov 2023 00:00:00 | |||||
Disease_info | Potential_model (22) | |||||
Molecular_info | Corresponding_CDS | C06G3.5a | ||||
C06G3.5b | ||||||
Corresponding_transcript | C06G3.5a.1 | |||||
C06G3.5b.1 | ||||||
C06G3.5b.2 | ||||||
Other_sequence (44) | ||||||
Associated_feature | WBsf646059 | |||||
WBsf655028 | ||||||
WBsf996869 | ||||||
WBsf996870 | ||||||
WBsf1017641 | ||||||
WBsf228489 | ||||||
WBsf228490 | ||||||
Experimental_info | RNAi_result | WBRNAi00010341 | Inferred_automatically | RNAi_primary | ||
WBRNAi00028594 | Inferred_automatically | RNAi_primary | ||||
WBRNAi00039937 | Inferred_automatically | RNAi_primary | ||||
Expr_pattern | Expr5192 | |||||
Expr1014251 | ||||||
Expr1036659 | ||||||
Expr1144011 | ||||||
Expr2000543 | ||||||
Expr2018769 | ||||||
Drives_construct | WBCnstr00003971 | |||||
WBCnstr00028758 | ||||||
Construct_product | WBCnstr00028758 | |||||
Microarray_results (26) | ||||||
Expression_cluster (200) | ||||||
Interaction (179) | ||||||
Map_info | Map | IV | Position | 3.27757 | ||
Positive | Positive_clone | C06G3 | Inferred_automatically | From sequence, transcript, pseudogene data | ||
Pseudo_map_position | ||||||
Reference | WBPaper00038491 | |||||
WBPaper00041771 | ||||||
WBPaper00055090 | ||||||
WBPaper00062899 | ||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||
Method | Gene |