ain-2 encodes, by alternative splicing, three isoforms of anunfamiliar protein paralogous to AIN-1, and homologous to Brugia malayi14748.m00068, 14052.m00191, and 14963.m01790; AIN-2 protein bindsGEI-4 and GEI-16 in yeast two-hybrid experiments; AIN-2 and itsnematode homologs have weak similarity to human TNRC6A (GW182;OMIM:610739) and Drosophila GAWKY; ain-2 has no obvious function inmass RNAi assays.
Involved in negative regulation of gene expression; regulation of cell fate specification; and regulation of development, heterochronic. Expressed widely.
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.