WormBase Tree Display for Gene: WBGene00014254
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| WBGene00014254 | SMap | S_parent | Sequence | ZK1320 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | cyp-13A10 | |||||||
| Sequence_name | ZK1320.4 | ||||||||
| Molecular_name | ZK1320.4 | ||||||||
| ZK1320.4.1 | |||||||||
| CE37736 | |||||||||
| Other_name | CELE_ZK1320.4 | Accession_evidence | NDB | BX284602 | |||||
| Public_name | cyp-13A10 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:55 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 21 Sep 2004 09:38:16 | WBPerson1971 | Name_change | CGC_name | cyp-13A10 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | cyp | ||||||||
| Allele (38) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00055359 | ||||||||
| 00055360 | |||||||||
| 00055361 | |||||||||
| 00055362 | |||||||||
| 00055363 | |||||||||
| 00055364 | |||||||||
| 00120967 | |||||||||
| 00120968 | |||||||||
| 00120969 | |||||||||
| 00120970 | |||||||||
| Ortholog (80) | |||||||||
| Paralog (12) | |||||||||
| Structured_description | Concise_description | cyp-13A10 encodes one of ~80 C. elegans cytochrome P450s: membrane-associated, heme-containing NADPH-dependent monooxygenases that catalyze the oxidative metabolism of a variety of exogenous and endogenous compounds. | Curator_confirmed | WBPerson1843 | |||||
| Date_last_updated | 20 Nov 2008 00:00:00 | ||||||||
| Automated_description | Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in several diseases, including Ghosal hematodiaphyseal syndrome; familial Mediterranean fever; and leukemia (multiple). Is an ortholog of several human genes including CYP3A4 (cytochrome P450 family 3 subfamily A member 4); CYP3A5 (cytochrome P450 family 3 subfamily A member 5); and CYP3A7 (cytochrome P450 family 3 subfamily A member 7). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:8552 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2638) | ||||
| DOID:3526 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11609) | ||||||
| DOID:2987 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2637) | ||||||
| DOID:9952 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2638) | ||||||
| DOID:0112251 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11609) | ||||||
| DOID:0080630 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2638) | ||||||
| DOID:10825 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2638) | ||||||
| DOID:1612 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2637) | ||||||
| Molecular_info | Corresponding_CDS | ZK1320.4 | |||||||
| Corresponding_CDS_history | ZK1320.4:wp78 | ||||||||
| ZK1320.4:wp134 | |||||||||
| Corresponding_transcript | ZK1320.4.1 | ||||||||
| Other_sequence | Tcol_isotig15615 | ||||||||
| CJC00249_1 | |||||||||
| PPC08967_1 | |||||||||
| Associated_feature | WBsf650448 | ||||||||
| WBsf650449 | |||||||||
| WBsf223686 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00092627 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00059235 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1012131 | ||||||||
| Expr1036391 | |||||||||
| Expr1162665 | |||||||||
| Expr2010678 | |||||||||
| Expr2028918 | |||||||||
| Drives_construct | WBCnstr00029187 | ||||||||
| Construct_product | WBCnstr00029187 | ||||||||
| Microarray_results (17) | |||||||||
| Expression_cluster (181) | |||||||||
| Interaction (27) | |||||||||
| Map_info (3) | |||||||||
| Reference | WBPaper00037579 | ||||||||
| WBPaper00038491 | |||||||||
| WBPaper00042257 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00062515 | |||||||||
| WBPaper00064598 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
