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WormBase Tree Display for Gene: WBGene00014254

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Name Class

WBGene00014254SMapS_parentSequenceZK1320
IdentityVersion2
NameCGC_namecyp-13A10
Sequence_nameZK1320.4
Molecular_nameZK1320.4
ZK1320.4.1
CE37736
Other_nameCELE_ZK1320.4Accession_evidenceNDBBX284602
Public_namecyp-13A10
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:55WBPerson1971EventImportedInitial conversion from CDS class of WS125
221 Sep 2004 09:38:16WBPerson1971Name_changeCGC_namecyp-13A10
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcyp
Allele (38)
RNASeq_FPKM (74)
GO_annotation00055359
00055360
00055361
00055362
00055363
00055364
00120967
00120968
00120969
00120970
Ortholog (80)
Paralog (12)
Structured_descriptionConcise_descriptioncyp-13A10 encodes one of ~80 C. elegans cytochrome P450s: membrane-associated, heme-containing NADPH-dependent monooxygenases that catalyze the oxidative metabolism of a variety of exogenous and endogenous compounds.Curator_confirmedWBPerson1843
Date_last_updated20 Nov 2008 00:00:00
Automated_descriptionPredicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in several diseases, including Ghosal hematodiaphyseal syndrome; familial Mediterranean fever; and leukemia (multiple). Is an ortholog of several human genes including CYP3A4 (cytochrome P450 family 3 subfamily A member 4); CYP3A5 (cytochrome P450 family 3 subfamily A member 5); and CYP3A7 (cytochrome P450 family 3 subfamily A member 7).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:8552Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2638)
DOID:3526Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11609)
DOID:2987Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2637)
DOID:9952Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2638)
DOID:0112251Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11609)
DOID:0080630Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2638)
DOID:10825Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2638)
DOID:1612Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2637)
Molecular_infoCorresponding_CDSZK1320.4
Corresponding_CDS_historyZK1320.4:wp78
ZK1320.4:wp134
Corresponding_transcriptZK1320.4.1
Other_sequenceTcol_isotig15615
CJC00249_1
PPC08967_1
Associated_featureWBsf650448
WBsf650449
WBsf223686
Experimental_infoRNAi_resultWBRNAi00092627Inferred_automaticallyRNAi_primary
WBRNAi00059235Inferred_automaticallyRNAi_primary
Expr_patternExpr1012131
Expr1036391
Expr1162665
Expr2010678
Expr2028918
Drives_constructWBCnstr00029187
Construct_productWBCnstr00029187
Microarray_results (17)
Expression_cluster (181)
InteractionWBInteraction000123289
WBInteraction000123378
WBInteraction000123493
WBInteraction000123536
WBInteraction000123582
WBInteraction000123609
WBInteraction000123637
WBInteraction000123669
WBInteraction000123737
WBInteraction000123757
WBInteraction000123776
WBInteraction000123794
WBInteraction000123811
WBInteraction000123827
WBInteraction000123885
WBInteraction000123925
WBInteraction000123933
WBInteraction000174304
WBInteraction000174452
WBInteraction000203290
WBInteraction000281239
WBInteraction000323409
WBInteraction000340732
WBInteraction000340742
WBInteraction000405312
WBInteraction000429306
WBInteraction000459562
Map_info (3)
ReferenceWBPaper00037579
WBPaper00038491
WBPaper00042257
WBPaper00055090
WBPaper00062515
WBPaper00064598
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene