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WormBase Tree Display for Gene: WBGene00014254

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Name Class

WBGene00014254SMapS_parentSequenceZK1320
IdentityVersion2
NameCGC_namecyp-13A10
Sequence_nameZK1320.4
Molecular_nameZK1320.4
ZK1320.4.1
CE37736
Other_nameCELE_ZK1320.4Accession_evidenceNDBBX284602
Public_namecyp-13A10
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:55WBPerson1971EventImportedInitial conversion from CDS class of WS125
221 Sep 2004 09:38:16WBPerson1971Name_changeCGC_namecyp-13A10
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcyp
Allele (38)
RNASeq_FPKM (74)
GO_annotation00055359
00055360
00055361
00055362
00055363
00055364
00120967
00120968
00120969
00120970
Ortholog (80)
Paralog (12)
Structured_descriptionConcise_descriptioncyp-13A10 encodes one of ~80 C. elegans cytochrome P450s: membrane-associated, heme-containing NADPH-dependent monooxygenases that catalyze the oxidative metabolism of a variety of exogenous and endogenous compounds.Curator_confirmedWBPerson1843
Date_last_updated20 Nov 2008 00:00:00
Automated_descriptionPredicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in several diseases, including Ghosal hematodiaphyseal syndrome; familial Mediterranean fever; and leukemia (multiple). Is an ortholog of several human genes including CYP3A4 (cytochrome P450 family 3 subfamily A member 4); CYP3A5 (cytochrome P450 family 3 subfamily A member 5); and CYP3A7 (cytochrome P450 family 3 subfamily A member 7).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:8552Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2638)
DOID:3526Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11609)
DOID:2987Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2637)
DOID:9952Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2638)
DOID:0112251Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11609)
DOID:0080630Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2638)
DOID:10825Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2638)
DOID:1612Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2637)
Molecular_infoCorresponding_CDSZK1320.4
Corresponding_CDS_historyZK1320.4:wp78
ZK1320.4:wp134
Corresponding_transcriptZK1320.4.1
Other_sequenceTcol_isotig15615
CJC00249_1
PPC08967_1
Associated_featureWBsf650448
WBsf650449
WBsf223686
Experimental_infoRNAi_resultWBRNAi00092627Inferred_automaticallyRNAi_primary
WBRNAi00059235Inferred_automaticallyRNAi_primary
Expr_patternExpr1012131
Expr1036391
Expr1162665
Expr2010678
Expr2028918
Drives_constructWBCnstr00029187
Construct_productWBCnstr00029187
Microarray_results (17)
Expression_clusterWBPaper00033065:cyc-1(RNAi)_upregulated
WBPaper00035269:cde-1_regulated
WBPaper00037682:sma-2_sma-4_upregulated
WBPaper00037950:all-neurons_embryo_enriched
WBPaper00037950:all-neurons_embryo_SelectivelyEnriched
WBPaper00037950:all-neurons_L1-larva_expressed
WBPaper00037950:all-neurons_L2-larva_expressed
WBPaper00037950:coelomocytes_L2-larva_expressed
WBPaper00037950:excretory-cell_L2-larva_expressed
WBPaper00037950:hypodermis_L3-L4-larva_expressed
WBPaper00038168:lin-15B(n744)_upregulated
WBPaper00038438:D.coniospora_12hr_upregulated_RNAseq
WBPaper00038438:P.lumniescens_24hr_upregulated_RNAseq
WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
WBPaper00042215:wdr-23(tm1817)_upregulated
WBPaper00042477:rsr-2(RNAi)_upregulated_TilingArray
WBPaper00044260:1-methylnicotinamide_upregulated
WBPaper00044316:CH3HgCl_7.5uM_upregulated
WBPaper00044736:oscillating_dev_expression
WBPaper00045050:drh-3 (ne4253)_upregulated
WBPaper00045316:prg-1_downregulated_L2
WBPaper00045417:128Q-huntingtin_downreglated
WBPaper00046024:sleep_downregulated_oscillating
WBPaper00046337:polysomal_daf-2_vs_daf-2;daf-16_downregulated
WBPaper00046337:polysomal_N2_vs_daf-2_downregulated
WBPaper00046415:lithium_downregulated
WBPaper00046497:B.thuringiensis_0.1mix_upregulated_6h
WBPaper00046497:B.thuringiensis_0.1mix_upregulated_12h
WBPaper00046497:B.thuringiensis_0.5mix_upregulated_6h
WBPaper00048611:MnCl2_upregulated
WBPaper00048690:hermaphrodite-Z1-Z4_enriched
WBPaper00048690:male-Z1-Z4_enriched
WBPaper00049498:npr-1(ur89)_regulated_7
WBPaper00049545:jmjd-3.1(+)_upregulated
WBPaper00049732:blmp-1(tm548);daf-7(e1372ts)_vs_daf-7(e1372ts)_downregulated
WBPaper00049954:BPS_upregulated
WBPaper00050332:juglone_upregulated
WBPaper00050332:skn-1(RNAi)_downregulated
WBPaper00050344:PLM-neuron_enriched
WBPaper00050370:dpy-21(e428)_L3_upregulated
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
WBPaper00050726:OsmoticStress_regulated_Food
WBPaper00050726:OsmoticStress_regulated_NoFood
WBPaper00050801:DAF-16_dauer_regulome
WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
WBPaper00050903:mir-35-41(nDf50)_25C_upregulated
WBPaper00051245:epidermis_cytoplasm_expressed
WBPaper00051245:intestine_cytoplasm_expressed
WBPaper00051388:Glucose-diet_upregulated
WBPaper00051558:aging_regulated
WBPaper00053295:lin-22(icb38)_upregulated
WBPaper00053295:lin-22(ot269)_upregulated
WBPaper00053318:mir-71(n4115)_upregulated_mRNA
WBPaper00053402:cco-1(RNAi)_upregulated
WBPaper00053606:N2_vs_elt-2(ca15)_downregulated
WBPaper00053798:nhr-49(nr2041)_tBOOH_upregulated
WBPaper00053810:clk-1(qm30)_upregulated
WBPaper00053810:daf-2(e1370)_upregulated
WBPaper00053810:isp-1(qm150)_upregulated
WBPaper00053810:nuo-6(qm200)_upregulated
WBPaper00053810:sod-2(ok1030)_upregulated
WBPaper00054758:alg-1(gk204)_upregulated
WBPaper00055013:hmg-4(RNAi)_upregulated
WBPaper00055137:S.maltophilia_downregulated
WBPaper00055354:eat-2(ad1116)_downregulated
WBPaper00055354:Psora-Allantoin_upregulated
WBPaper00055354:Psora_upregulated
WBPaper00055354:Rapamycin-Psora-Allantoin_upregulated
WBPaper00055354:Rapamycin-Psora_upregulated
WBPaper00055354:Rapamycin-Rifampicin-Allantoin_upregulated
WBPaper00055354:Rapamycin-Rifampicin-Psora_upregulated
WBPaper00055354:Rapamycin-Rifampicin_upregulated
WBPaper00055354:Rifampicin-Psora_upregulated
WBPaper00055354:Rifampicin_upregulated
WBPaper00055626:pry-1(mu38)_downregulated
WBPaper00055862:antimycin_damt-1(gk961032)_regulated
WBPaper00055941:nuo-6(qm200);atfs-1(gk3094)_upregulated
WBPaper00055941:nuo-6(qm200)_upregulated
WBPaper00056330:glycine_downregulated
WBPaper00056443:sek-1(km4)_upregulated
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
WBPaper00056617:adr-1_upregulated_L4_transcript
WBPaper00056826:SGP_biased
WBPaper00057041:spc-1(cas971)_downregulated
WBPaper00057041:unc-70(cas983)_downregulated
WBPaper00057068:ints-4(RNAi)_upregulated
WBPaper00057068:numr-1(RNAi)_downregulated
WBPaper00057068:numr-1(RNAi)_downregulated_Cadmium
WBPaper00058598:sin-3(tm1276)_downregulated
WBPaper00058725:sftb-1(cer6)_upregulated
WBPaper00058948:PA14_downregulated
WBPaper00058969:RIS_depleted
WBPaper00059117:B.subtilis_downregulated
WBPaper00059191:hsp-16.2p-LIN-29_downregulated
WBPaper00059421:daf-1(m40);daf-3(mgDf90)_downregulated
WBPaper00059421:daf-3(mgDf90)_downregulated
WBPaper00059471:EGL-43_interacting
WBPaper00059664:srbc-48(ac23)_upregulated
WBPaper00059754:P.aeruginosa_PA14_upregulated
WBPaper00059824:rnp-6(dh1127)_regulated_OP50
WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
WBPaper00059839:S.maltophilia_regulated
WBPaper00059895:wounding_upregulated
WBPaper00060014:set-2(tm1630)_downregulated
WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
WBPaper00060434:pH4.33_vs_pH6.33_uprgulated
WBPaper00060445:ikb-1(nr2027)_downregulated_L4
WBPaper00060445:ikb-1(nr2027)_upregulated_L1
WBPaper00060445:nfki-1(cer1)_ikb-1(nr2027)_downregulated_L4
WBPaper00060661:sensory-neuron_enriched
WBPaper00060703:nas-38(ok3407)_upregulated
WBPaper00060909:atfs-1(cmh15)_downregulated
WBPaper00061203:let-418(n3536)_upregulated
WBPaper00061203:sin-3(tm1276)_upregulated
WBPaper00061203:spr-1(ok2144)_upregulated
WBPaper00061340:hyp7_AB_lineage
WBPaper00061340:hyp7_C_lineage
WBPaper00061340:P_cell
WBPaper00061341:28C_24h_upregulated
WBPaper00061341:28C_48h_upregulated
WBPaper00061390:N2_ascarosides_downregulated
WBPaper00061479:hda-1(ne4752)_upregulated
WBPaper00061479:mep-1(ne4629)_upregulated
WBPaper00061527:syd-1_2945-unc-41_2170
WBPaper00061653:alh-4(hj221)_upregulated
WBPaper00061753:csr-1(tor159)_upregulated_20C
WBPaper00061800:miR-85(n4117)_downregulated_20C
WBPaper00062146:MOG-7-degron_2h_regulated
WBPaper00062159:hda-2(ok1479)_upregulated
WBPaper00062325:muscle_depleted_coding-RNA
WBPaper00062345:bortezomib_4h_upregulated_zip-1(jy13)
WBPaper00062354:H.zoospora_6h_regulated
WBPaper00062446:nhr-8(hd117)_upregulated
WBPaper00062497:xpf-1(tm2842)_upregulated
WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
WBPaper00064107:lin-35(n745)_upregulated
WBPaper00064130:Beta-Amyloid_24h_downregulated_mRNA
WBPaper00064539:nhr-114(gk849)_upregulated
WBPaper00064788:ketamine_upregulated
WBPaper00064933:bcf-1(ylf1)_upregulated_transcript
WBPaper00065096:Day10_vs_Day1_upregulated
WBPaper00065096:npr-8(ok1439)_upregulated_Day1_20C
WBPaper00065841:33_0
WBPaper00065841:79_0
WBPaper00066062:xrep-4(lax137)_upregulated
WBPaper00066232:ash-2(RNAi)_downregulated_WT
cgc4489_group_21
WBPaper00024393:strongly_regulated_dauer_genes
WBPaper00025141:N2_Expressed_Genes
WBPaper00025141:unc-4::GFP_Expressed_Genes
WBPaper00026929:Resveratrol_regulated_daf-16
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00031003:hlh_1_enriched
WBPaper00031832:slr-2_regulated
WBPaper00034739:N2lessDR1350
WBPaper00036130:mir-243_up_regulated
WBPaper00036286:Pattern_F
WBPaper00037113:Diazinon_16C_regulated
WBPaper00041002:HF_11d_0.2mM_Up
WBPaper00041606:CE_X.nematophila_regulated
WBPaper00041939:control_vs_EtBr-exposed_48h
WBPaper00041939:control_vs_UVC-exposed_51h
WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_48h
WBPaper00044091:Bpseudomallei_induced_8h
WBPaper00044091:Bpseudomallei_induced_12h
WBPaper00045263:nuo-6(qm200)_upregulated
WBPaper00045673:colistin_upregulated
WBPaper00045960:L1-L4-lethargus_downregulated
WBPaper00045960:L4-lethargus_downregulated
WBPaper00046548:dafachronic-acid_upregulated
WBPaper00047070:N2_starvation_downregulated
WBPaper00047070:N2_UV_upregulated
WBPaper00047070:xpa-1_UV_upregulated
WBPaper00048989:eat-2(ad465)_rapamycin_downregulated
WBPaper00053827:pyoverdine_upregulated
Interaction (27)
Map_infoMapIIPosition1.6365Error0.002261
PositivePositive_cloneZK1320Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00037579
WBPaper00038491
WBPaper00042257
WBPaper00055090
WBPaper00062515
WBPaper00064598
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene