WormBase Tree Display for Gene: WBGene00013218

WBGene00013218 SMap: S_parent: Sequence: Y54G11A
  Identity: Version: 1
    Name: Sequence_name: Y54G11A.9
      Molecular_name: Y54G11A.9
        Y54G11A.9.1
        CE35683
        Y54G11A.9.2
      Other_name: CELE_Y54G11A.9 Accession_evidence: NDB BX284602
      Public_name: Y54G11A.9
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:54 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
    Status: Live
  Gene_info: Biotype: SO:0001217
    Allele (36)
    RNASeq_FPKM (74)
    GO_annotation: 00102961
      00102962
      00102963
      00102964
      00102965
      00102966
      00120119
      00120120
    Contained_in_operon: CEOP2636
    Ortholog (33)
    Paralog: WBGene00045279 Caenorhabditis elegans From_analysis: modENCODE_Pseudogenes
      WBGene00012666 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Automated_description: Predicted to enable 2 iron, 2 sulfur cluster binding activity; 4 iron, 4 sulfur cluster binding activity; and iron ion binding activity. Predicted to be involved in iron-sulfur cluster assembly and protein maturation by [4Fe-4S] cluster transfer. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in multiple mitochondrial dysfunctions syndrome 4. Is an ortholog of human ISCA2 (iron-sulfur cluster assembly 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0080136 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:19857)
  Molecular_info: Corresponding_CDS: Y54G11A.9
    Corresponding_CDS_history: Y54G11A.9:wp109
    Corresponding_transcript: Y54G11A.9.1
      Y54G11A.9.2
    Other_sequence (25)
    Associated_feature: WBsf990684
      WBsf1013828
      WBsf224264
      WBsf224265
  Experimental_info: RNAi_result: WBRNAi00024222 Inferred_automatically: RNAi_primary
      WBRNAi00024149 Inferred_automatically: RNAi_primary
      WBRNAi00023349 Inferred_automatically: RNAi_primary
      WBRNAi00020465 Inferred_automatically: RNAi_primary
      WBRNAi00057434 Inferred_automatically: RNAi_primary
      WBRNAi00023862 Inferred_automatically: RNAi_primary
      WBRNAi00037489 Inferred_automatically: RNAi_primary
      WBRNAi00020990 Inferred_automatically: RNAi_primary
      WBRNAi00062452 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1020954
      Expr1160870
      Expr2007930
      Expr2026172
    Microarray_results (19)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_downregulated
      WBPaper00032031:DConiospora_upregulated_cDNA_24h
      WBPaper00032031:DConiospora_upregulated_OligoArray_24h
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00033131:dapk-1_upregulated
      WBPaper00035073:mitochondria_protein
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:bodywall-muscle_larva_enriched
      WBPaper00037950:bodywall-muscle_larva_SelectivelyEnriched
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038438:P.lumniescens_24hr_downregulated_RNAseq
      WBPaper00041370:spg-7(RNAi)_upregulated_atfs-1_dependent
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044736:flat_dev_expression
      WBPaper00046509:htz-1(ok3099)_downregulated
      WBPaper00046509:lin-35(n745)_downregulated
      WBPaper00048988:neuron_expressed
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050801:DAF-12_dauer_regulome
      WBPaper00050801:DPY-21_dauer_regulome
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00051039:germline_enriched
      WBPaper00051265:F4_morc-1(tm6048)_upregulated
      WBPaper00052884:emb-4(hc60)_downregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053321:nos-1(gv5)nos-2(RNAi)_downregulated_L1_SMARTseq
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00055354:eat-2(ad1116)_upregulated
      WBPaper00055354:Rapamycin-Allantoin_upregulated
      WBPaper00055354:Rapamycin_upregulated
      WBPaper00055354:Rifampicin-Allantoin_upregulated
      WBPaper00055648:germline_expressed
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00056809:smn-1(ok355)_downregulated
      WBPaper00057288:Cold_downregulated_transcript
      WBPaper00058691:cfp-1(tm6369)_upregulated
      WBPaper00058691:sin-3(tm1276)_upregulated
      WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
      WBPaper00059664:srbc-48(ac23)_downregulated
      WBPaper00060909:atfs-1(et18)_upregulated
      WBPaper00061340:Pharyngeal_marginal_cell
      WBPaper00061527:F31C3.4_6048-cutc-1_15804
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064716:paraquat_upregulated
      WBPaper00065096:Day10_vs_Day1_upregulated
      WBPaper00065749:Heat-Shock_upregulated_endu-2(tm4977)
      WBPaper00065975:P-body_vs_oocyte_enriched
      WBPaper00065975:P-body_vs_WholeAnimal_enriched
      WBPaper00065993:glp-1(e2141)_downregulated
      WBPaper00025032:cluster_147
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00035905:FBF-1_Associated
      WBPaper00037611:RNP-8-associated
      WBPaper00040963:TA300_down
      WBPaper00041370:spg-7(RNAi)_upregulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00045263:isp-1(qm150)_upregulated
      WBPaper00045263:nuo-6(qm200)_upregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_upregulated
      WBPaper00048989:N2_allantoin_upregulated
      WBPaper00048989:N2_rapamycin_downregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      [cgc6390]:mixed_oogenesis-somatic
    Interaction (38)
  Map_info: Positive: Positive_clone: Y54G11A Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: II 22.9058
  Reference: WBPaper00038491
    WBPaper00055090
  Method: Gene