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WormBase Tree Display for Gene: WBGene00012777

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Name Class

WBGene00012777SMapS_parentSequenceY42A5A
IdentityVersion2
NameCGC_namelact-8Person_evidenceWBPerson168
Sequence_nameY42A5A.2
Molecular_nameY42A5A.2a
Y42A5A.2a.1
CE43119
Y42A5A.2b
CE45998
Y42A5A.2c
CE46035
Y42A5A.2b.1
Y42A5A.2c.1
Other_nameCELE_Y42A5A.2Accession_evidenceNDBBX284605
Public_namelact-8
DB_infoDatabaseAceViewgene5L568
WormQTLgeneWBGene00012777
WormFluxgeneWBGene00012777
NDBlocus_tagCELE_Y42A5A.2
PanthergeneCAEEL|WormBase=WBGene00012777|UniProtKB=Q9XWZ6
familyPTHR46825
NCBIgene189839
RefSeqproteinNM_001269357.3
NM_001269359.3
NM_001269358.3
TREEFAMTREEFAM_IDTF315050
TrEMBLUniProtAccF3Y5Q9
Q9XWZ6
F3Y5Q8
UniProt_GCRPUniProtAccQ9XWZ6
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:54WBPerson1971EventImportedInitial conversion from CDS class of WS125
213 Apr 2007 16:02:30WBPerson2970Name_changeCGC_namelact-8
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classlact
Allele (53)
StrainWBStrain00037741
RNASeq_FPKM (74)
Ortholog (24)
ParalogWBGene00008047Caenorhabditis elegansFrom_analysisTreeFam
WormBase-Compara
WBGene00012890Caenorhabditis elegansFrom_analysisTreeFam
WormBase-Compara
Structured_descriptionConcise_descriptionlact-8 encodes a beta-lactamase domain-containing protein that contains a predicted transmembrane domain in its N terminus.Curator_confirmedWBPerson1843
Date_last_updated18 Dec 2007 00:00:00
Automated_descriptionEnriched in several structures, including ABarpaapap; ABarpaappa; ABarpaappp; anterior hypodermis; and carbon dioxide sensory neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-2; skn-1; and glp-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including levamisole; allantoin; and Sirolimus based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Beta-lactamase-related; Beta-lactamase; and Beta-lactamase/transpeptidase-like.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSY42A5A.2a
Y42A5A.2b
Y42A5A.2c
Corresponding_CDS_historyY42A5A.2:wp195
Corresponding_transcriptY42A5A.2a.1
Y42A5A.2b.1
Y42A5A.2c.1
Other_sequenceHBC25388_1
JI178465.1
Dviv_isotig29914
ES743304.1
Associated_featureWBsf653076
WBsf669356
WBsf1001266
Experimental_infoRNAi_resultWBRNAi00056428Inferred_automaticallyRNAi_primary
WBRNAi00095078Inferred_automaticallyRNAi_primary
WBRNAi00020511Inferred_automaticallyRNAi_primary
WBRNAi00056425Inferred_automaticallyRNAi_primary
WBRNAi00037016Inferred_automaticallyRNAi_primary
WBRNAi00037017Inferred_automaticallyRNAi_primary
Expr_patternExpr1011809
Expr1035654
Expr1159909
Expr2013000
Expr2031232
Drives_constructWBCnstr00029848
Construct_productWBCnstr00029848
Microarray_results (20)
Expression_clusterWBPaper00031040:TGF-beta_adult_upregulated
WBPaper00038438:D.coniospora_12hr_downregulated_RNAseq
WBPaper00038438:E.faecalis_24hr_upregulated_RNAseq
WBPaper00038438:P.lumniescens_24hr_upregulated_RNAseq
WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
WBPaper00042561:smg-2(RNAi)_upregulated
WBPaper00044736:oscillating_dev_expression
WBPaper00045017:blmp-1(tm548)_downregulated
WBPaper00045050:csr-1(hypomorph)_downregulated
WBPaper00045774:clk-1_upregulated
WBPaper00046121:endoderm_unique
WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
WBPaper00046499:AMPK_regulated
WBPaper00047132:glp-1(ts)-25C_upregulated
WBPaper00049018:ham-3(RNAi)_downregulated
WBPaper00049018:swsn-2.2(RNAi)_downregulated
WBPaper00049368:daf-2(e1370)_downregulated
WBPaper00049942:hsf-1(RNAi)_downregulated
WBPaper00050344:AFD-neuron_enriched
WBPaper00050344:ASER-neuron_enriched
WBPaper00050370:dpy-21(e428)_L3_downregulated
WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050488:daf-2(e1370)_vs_daf-2(e1370);mir-34(gk437)_regulated_dauer_25C
WBPaper00050726:OsmoticStress_regulated_Food
WBPaper00050726:OsmoticStress_regulated_NoFood
WBPaper00050801:DAF-12_dauer_regulome
WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
WBPaper00050990:hypodermis_enriched
WBPaper00050990:hypodermis_expressed
WBPaper00051257:Levamisole_upregulated
WBPaper00052884:emb-4(hc60)_upregulated
WBPaper00053184:sma-4(rax3)_upregulated
WBPaper00053308:SMG-2_associated_NMD(-)_unaltered_ClassII
WBPaper00053402:cco-1(RNAi)_downregulated
WBPaper00054872:egl-9(sa307)_downregulated
WBPaper00055013:hmg-3(bar24)_downregulated
WBPaper00055226:ADR-2_target_N2
WBPaper00055354:Rapamycin-Allantoin_downregulated
WBPaper00055354:Rapamycin_downregulated
WBPaper00055354:Rifampicin_upregulated
WBPaper00055386:daf-2(e1370)_upregulated
WBPaper00055482:Tunicamycin_downregulated
WBPaper00055941:atfs-1(et15)_upregulated
WBPaper00055971:nhl-2(ok818)_20C_upregulated
WBPaper00056169:rrf-3(pk1426)_downregulated_L4
WBPaper00056284:ints-1(RNAi)_downregulated
WBPaper00056290:hsp-6(mg585)_upregulated
WBPaper00056326:zip-3(gk3164)_upregulated_P.aeruginosa-infected
WBPaper00056330:glycine_downregulated
WBPaper00056443:sek-1(km4)_upregulated
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
WBPaper00056471:S.aureus-4h_upregulated_N2
WBPaper00057041:unc-70(cas983)_upregulated
WBPaper00057068:ints-4(RNAi)_downregulated_Cadmium
WBPaper00057154:HeatShock_upregulated_mRNA
WBPaper00058598:mex-1(or286)_upregulated
WBPaper00058598:mex-3(eu149)_upregulated
WBPaper00058598:sin-3(tm1276)_downregulated
WBPaper00058598:spn-4(tm291)_upregulated
WBPaper00058711:wdr-5(ok1417)_upregulated
WBPaper00058948:npr-8(ok1439)_downregulated_OP50
WBPaper00058948:npr-8(ok1439)_downregulated_PA14
WBPaper00058969:RIS_depleted
WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
WBPaper00059421:daf-3(mgDf90)_downregulated
WBPaper00059566:wdr-23(mac32)_upregulated
WBPaper00059664:srbc-48(ac23)_upregulated
WBPaper00059739:hira-1(gk835598)_downregulated_L4
WBPaper00059895:wounding_downregulated
WBPaper00059987:Wounding_downregulated
WBPaper00060014:set-2(tm1630)_downregulated
WBPaper00060273:isp-1(qm150)_upregulated
WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
WBPaper00060526:plp-1(ok2155)_upregulated
WBPaper00060683:hlh-11(ko1)_upregulated
WBPaper00060811:L1_vs_adult_downregulated_neural
WBPaper00060921:cat-2(e1112)_downregulated
WBPaper00061007:HB101_upregulated
WBPaper00061007:HB115_upregulated
WBPaper00061007:S.aquatilis_upregulated
WBPaper00061203:sin-3(tm1276)_upregulated
WBPaper00061203:spr-1(ok2144)_upregulated
WBPaper00061340:hyp4_hyp5_hyp6
WBPaper00061340:hyp7_AB_lineage
WBPaper00061340:Seam_cell
WBPaper00061340:T
WBPaper00061527:col-128-cdh-10_9234
WBPaper00061530:nhr-49(e2144)_downregulated
WBPaper00061692:acivicin_upregulated
WBPaper00062156:jmjd-1.2(zr1010)_upregulated
WBPaper00062156:jmjd-5(zr1234)_upregulated
WBPaper00062159:hda-2(ok1479)_upregulated
WBPaper00062193:skn-1(RNAi)_downregulated
WBPaper00062325:muscle_depleted_coding-RNA
WBPaper00062345:bortezomib_4h_downregulated_N2
WBPaper00062347:blmp-1(tm548)_downregulated
WBPaper00062446:nhr-8(hd117)_upregulated
WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20)
WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
WBPaper00064107:lin-35(n745)_downregulated
WBPaper00064306:Agaro-oligosaccharides_upregulated
WBPaper00064632:daf-2(e1370)_upregulated_intestine
WBPaper00064716:paraquat_downregulated
WBPaper00064769:him-17(me24)_upregulated
WBPaper00065096:25C_vs_20C_downregulated
WBPaper00065096:Day10_vs_Day1_downregulated
WBPaper00065096:npr-8(ok1439)_downregulated_Day10_20C
WBPaper00065199:Transgeneration-starvation_regulated_fed
WBPaper00065734:unc-25(e156)_downregulated
WBPaper00065746:eat-2(ad1113)_downregulated
WBPaper00065749:endu-2(tm4977)_upregulated
WBPaper00065841:37_0
WBPaper00065841:79_0
WBPaper00065841:82_0
WBPaper00065841:97_0
WBPaper00065975:P-body_vs_WholeAnimal_depleted
WBPaper00065993:glp-1(e2141)_upregulated
WBPaper00066110:tetraploid_vs_diploid_upregulated
WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
WBPaper00066232:ash-2(RNAi)_downregulated_WT
WBPaper00066232:hsf-1(RNAi)_upregulated_ash-2
cgc4489_group_7
WBPaper00025141:N2_Expressed_Genes
WBPaper00026952:class_E
WBPaper00026980:intestine_enriched
WBPaper00035873:dpy-9_regulated
WBPaper00036130:mir-243_up_regulated
WBPaper00036286:Pattern_C
WBPaper00036464:S.aureus-RN6390_regulated
WBPaper00037695:WC_5-day
WBPaper00038172:crh-1null_down_regulated
WBPaper00038304:octr-1_regulated
WBPaper00040876:mir-35_downregulated
WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
WBPaper00045263:0.1mM-paraquat_downregulated
WBPaper00045673:colistin_upregulated
WBPaper00046083:oga-1(ok1207)_OP50_downregulated
WBPaper00046083:pmk-1(km25)_OP50_downregulated
WBPaper00048989:N2_rapamycin_upregulated
WBPaper00055899:nitroguanidine_regulated
WBPaper00056330:mrps-5(RNAi)_upregulated
[cgc6390]:Cluster_B
Interaction (18)
Map_infoMapVPosition2.94611Error0.000565
PositivePositive_cloneY42A5AInferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene