WormBase Tree Display for Gene: WBGene00012354
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| WBGene00012354 | SMap | S_parent | Sequence | W09C5 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | cox-4 | Person_evidence | WBPerson117 | |||||
| WBPerson7169 | |||||||||
| Sequence_name | W09C5.8 | ||||||||
| Molecular_name | W09C5.8 | ||||||||
| W09C5.8.1 | |||||||||
| CE20171 | |||||||||
| Other_name | CELE_W09C5.8 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | cox-4 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:53 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 05 Sep 2017 13:25:30 | WBPerson2970 | Name_change | CGC_name | cox-4 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | cox | ||||||||
| Allele (24) | |||||||||
| Strain | WBStrain00037231 | ||||||||
| WBStrain00022511 | |||||||||
| WBStrain00047268 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00099906 | ||||||||
| 00099907 | |||||||||
| 00099908 | |||||||||
| 00099909 | |||||||||
| 00099910 | |||||||||
| 00099911 | |||||||||
| 00099912 | |||||||||
| 00099913 | |||||||||
| 00119507 | |||||||||
| 00119508 | |||||||||
| Ortholog (44) | |||||||||
| Structured_description | Concise_description | W09C5.8 encodes the C. elegans ortholog of the cytochrome c oxidase (COX) subunit IV (COX IV); loss of W09C5.8 activity via RNAi results in a shortened life span, reduced fertility, and defects in mitochondrial respiratory chain function. | Paper_evidence | WBPaper00032427 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 08 Nov 2010 00:00:00 | ||||||||
| Automated_description | Involved in mitochondrial electron transport, cytochrome c to oxygen. Predicted to be located in mitochondrial inner membrane. Predicted to be part of mitochondrial respiratory chain complex IV. Human ortholog(s) of this gene implicated in cytochrome-c oxidase deficiency disease. Is an ortholog of human COX4I1 (cytochrome c oxidase subunit 4I1) and COX4I2 (cytochrome c oxidase subunit 4I2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0070501 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2265) | ||||
| Molecular_info | Corresponding_CDS | W09C5.8 | |||||||
| Corresponding_transcript | W09C5.8.1 | ||||||||
| Other_sequence (131) | |||||||||
| Associated_feature | WBsf649714 | ||||||||
| WBsf655327 | |||||||||
| WBsf220533 | |||||||||
| WBsf220534 | |||||||||
| WBsf220535 | |||||||||
| Experimental_info | RNAi_result (21) | ||||||||
| Expr_pattern | Expr1028081 | ||||||||
| Expr1035471 | |||||||||
| Expr1158573 | |||||||||
| Expr2006884 | |||||||||
| Expr2025111 | |||||||||
| Drives_construct | WBCnstr00029984 | ||||||||
| Construct_product | WBCnstr00029984 | ||||||||
| Microarray_results (23) | |||||||||
| Expression_cluster (110) | |||||||||
| Interaction (76) | |||||||||
| Map_info | Map | I | Position | 21.6359 | |||||
| Positive | Positive_clone | W09C5 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (15) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
