WormBase Tree Display for Gene: WBGene00012354
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WBGene00012354 | SMap | S_parent | Sequence | W09C5 | ||
---|---|---|---|---|---|---|
Identity (6) | ||||||
Gene_info | Biotype | SO:0001217 | ||||
Gene_class | cox | |||||
Allele (24) | ||||||
Strain | WBStrain00037231 | |||||
WBStrain00022511 | ||||||
WBStrain00047268 | ||||||
RNASeq_FPKM (74) | ||||||
GO_annotation | 00099906 | |||||
00099907 | ||||||
00099908 | ||||||
00099909 | ||||||
00099910 | ||||||
00099911 | ||||||
00099912 | ||||||
00099913 | ||||||
00119507 | ||||||
00119508 | ||||||
Ortholog (44) | ||||||
Structured_description | Concise_description | W09C5.8 encodes the C. elegans ortholog of the cytochrome c oxidase (COX) subunit IV (COX IV); loss of W09C5.8 activity via RNAi results in a shortened life span, reduced fertility, and defects in mitochondrial respiratory chain function. | Paper_evidence | WBPaper00032427 | ||
Curator_confirmed | WBPerson1843 | |||||
Date_last_updated | 08 Nov 2010 00:00:00 | |||||
Automated_description | Involved in mitochondrial electron transport, cytochrome c to oxygen. Predicted to be located in mitochondrial inner membrane. Predicted to be part of mitochondrial respiratory chain complex IV. Human ortholog(s) of this gene implicated in cytochrome-c oxidase deficiency disease. Is an ortholog of human COX4I1 (cytochrome c oxidase subunit 4I1) and COX4I2 (cytochrome c oxidase subunit 4I2). | Paper_evidence | WBPaper00065943 | |||
Curator_confirmed | WBPerson324 | |||||
WBPerson37462 | ||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | |||||
Date_last_updated | 29 Nov 2023 00:00:00 | |||||
Disease_info | Potential_model | DOID:0070501 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2265) | |
Molecular_info | Corresponding_CDS | W09C5.8 | ||||
Corresponding_transcript | W09C5.8.1 | |||||
Other_sequence (131) | ||||||
Associated_feature | WBsf649714 | |||||
WBsf655327 | ||||||
WBsf220533 | ||||||
WBsf220534 | ||||||
WBsf220535 | ||||||
Experimental_info | RNAi_result (21) | |||||
Expr_pattern | Expr1028081 | |||||
Expr1035471 | ||||||
Expr1158573 | ||||||
Expr2006884 | ||||||
Expr2025111 | ||||||
Drives_construct | WBCnstr00029984 | |||||
Construct_product | WBCnstr00029984 | |||||
Microarray_results (23) | ||||||
Expression_cluster (110) | ||||||
Interaction (76) | ||||||
Map_info | Map | I | Position | 21.6359 | ||
Positive | Positive_clone | W09C5 | Inferred_automatically | From sequence, transcript, pseudogene data | ||
Pseudo_map_position | ||||||
Reference (15) | ||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||
Method | Gene |