WormBase Tree Display for Gene: WBGene00012354
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WBGene00012354 | SMap | S_parent | Sequence | W09C5 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name | CGC_name | cox-4 | Person_evidence | WBPerson117 | |||||
WBPerson7169 | |||||||||
Sequence_name | W09C5.8 | ||||||||
Molecular_name | W09C5.8 | ||||||||
W09C5.8.1 | |||||||||
CE20171 | |||||||||
Other_name | CELE_W09C5.8 | Accession_evidence | NDB | BX284601 | |||||
Public_name | cox-4 | ||||||||
DB_info | Database (11) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 26 May 2004 16:54:53 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
2 | 05 Sep 2017 13:25:30 | WBPerson2970 | Name_change | CGC_name | cox-4 | ||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | cox | ||||||||
Allele (24) | |||||||||
Strain | WBStrain00037231 | ||||||||
WBStrain00022511 | |||||||||
WBStrain00047268 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation | 00099906 | ||||||||
00099907 | |||||||||
00099908 | |||||||||
00099909 | |||||||||
00099910 | |||||||||
00099911 | |||||||||
00099912 | |||||||||
00099913 | |||||||||
00119507 | |||||||||
00119508 | |||||||||
Ortholog (44) | |||||||||
Structured_description | Concise_description | W09C5.8 encodes the C. elegans ortholog of the cytochrome c oxidase (COX) subunit IV (COX IV); loss of W09C5.8 activity via RNAi results in a shortened life span, reduced fertility, and defects in mitochondrial respiratory chain function. | Paper_evidence | WBPaper00032427 | |||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 08 Nov 2010 00:00:00 | ||||||||
Automated_description | Involved in mitochondrial electron transport, cytochrome c to oxygen. Predicted to be located in mitochondrial inner membrane. Predicted to be part of mitochondrial respiratory chain complex IV. Human ortholog(s) of this gene implicated in cytochrome-c oxidase deficiency disease. Is an ortholog of human COX4I1 (cytochrome c oxidase subunit 4I1) and COX4I2 (cytochrome c oxidase subunit 4I2). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:0070501 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2265) | ||||
Molecular_info | Corresponding_CDS | W09C5.8 | |||||||
Corresponding_transcript | W09C5.8.1 | ||||||||
Other_sequence (131) | |||||||||
Associated_feature | WBsf649714 | ||||||||
WBsf655327 | |||||||||
WBsf220533 | |||||||||
WBsf220534 | |||||||||
WBsf220535 | |||||||||
Experimental_info | RNAi_result (21) | ||||||||
Expr_pattern | Expr1028081 | ||||||||
Expr1035471 | |||||||||
Expr1158573 | |||||||||
Expr2006884 | |||||||||
Expr2025111 | |||||||||
Drives_construct | WBCnstr00029984 | ||||||||
Construct_product | WBCnstr00029984 | ||||||||
Microarray_results | SMD_W09C5.8 | ||||||||
178348_s_at | |||||||||
A_12_P106700 | |||||||||
A_12_P139600 | |||||||||
A_12_P139601 | |||||||||
A_12_P139602 | |||||||||
A_12_P139603 | |||||||||
A_12_P139604 | |||||||||
Aff_W09C5.8 | |||||||||
GPL13394_WBGene00012354 | |||||||||
GPL13914_W09C5.8 | |||||||||
GPL14144_W09C5.8_206-265_0.851_3_B | |||||||||
GPL14144_W09C5.8_427-486_0.723_9_C | |||||||||
GPL14144_W09C5.8_475-534_0.973_1_A | |||||||||
GPL19516_CGZ0038895 | |||||||||
GPL21109_W09C5.8 | |||||||||
GPL3518_CE20171 | |||||||||
GPL8304_CE_WBGene00012354_A | |||||||||
GPL8673_W09C5_8P00003 | |||||||||
GPL8673_W09C5_8P00179 | |||||||||
GPL8673_W09C5_8P00458 | |||||||||
GPL9450_W09C5.8 | |||||||||
cea2.c.06888 | |||||||||
Expression_cluster (110) | |||||||||
Interaction (76) | |||||||||
Map_info | Map | I | Position | 21.6359 | |||||
Positive | Positive_clone | W09C5 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Pseudo_map_position | |||||||||
Reference (15) | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |