WormBase Tree Display for Gene: WBGene00012005

WBGene00012005 SMap: S_parent: Sequence: CHROMOSOME_II
  Identity: Version: 4
    Name: CGC_name: jun-1 Person_evidence: WBPerson2962
            WBPerson443
      Sequence_name: T24H10.7
      Molecular_name (27)
      Other_name: CELE_T24H10.7 Accession_evidence: NDB BX284602
      Public_name: jun-1
    DB_info: Database: AceView gene 2J421
        WormQTL gene WBGene00012005
        WormFlux gene WBGene00012005
        NDB locus_tag CELE_T24H10.7
        Panther gene CAEEL|WormBase=WBGene00012005|UniProtKB=G5ECU7
          family PTHR11462
        NCBI gene 174452
        RefSeq protein NM_001356878.3
            NM_001356880.3
            NM_001136355.4
            NM_001356881.3
            NM_001383910.2
            NM_001356879.3
            NM_001027195.4
            NM_001027197.5
            NM_001027196.5
        SwissProt UniProtAcc G5ECU7
        TrEMBL UniProtAcc A0A2C9C3K0
            A0A2C9C3E7
            A0A2C9C2T0
            A0A2C9C2Y8
        UniProt_GCRP UniProtAcc G5ECU7
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:53 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 29 Nov 2004 12:57:28 WBPerson1983 Event: Acquires_merge: WBGene00012001
        3 27 Apr 2007 10:10:56 WBPerson1983 Event: Acquires_merge: WBGene00012006
        4 07 Nov 2007 09:36:21 WBPerson2970 Name_change: CGC_name: jun-1
      Acquires_merge (2)
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: jun
    Allele: WBVar00754350
      WBVar00227681
      WBVar00174439
      WBVar00227682
      WBVar00174440
      WBVar00754351
      WBVar00227683
      WBVar00754352
      WBVar00174441
      WBVar01499702
      WBVar00227684
      WBVar00174442
      WBVar00754353
      WBVar02040275
      WBVar00227686
      WBVar00754354
      WBVar00174443
      WBVar00174444
      WBVar00754355
      WBVar00754356
      WBVar00174445
      WBVar00258551
      WBVar00754357
      WBVar00174446
      WBVar00754358
      WBVar00174447
      WBVar00174448
      WBVar00754359
      WBVar00754360
      WBVar00174449
      WBVar01604409
      WBVar00754361
      WBVar00754362
      WBVar00754363
      WBVar00754364
      WBVar00754365
      WBVar00373476
      WBVar00552069
      WBVar00754366
      WBVar00373477
      WBVar00754367
      WBVar00552075
      WBVar00754368
      WBVar00373478
      WBVar00552082
      WBVar00373479
      WBVar00754369
      WBVar00754370
      WBVar00373480
      WBVar00255987
      WBVar00754371
      WBVar00373481
      WBVar00754372
      WBVar00373482
      WBVar00373483
      WBVar00251012
      WBVar00754373
      WBVar00373484
      WBVar01498435
      WBVar00754374
      WBVar00754375
      WBVar00373485
      WBVar00754376
      WBVar00373486
      WBVar00373487
      WBVar00754377
      WBVar00754378
      WBVar00373488
      WBVar00754379
      WBVar00373489
      WBVar00754380
      WBVar00373490
      WBVar00754381
      WBVar00373491
      WBVar00257841
      WBVar00373492
      WBVar00754382
      WBVar00268888
      WBVar00754383
      WBVar00373493
      WBVar00268889
      WBVar01960158
      WBVar00754384
      WBVar00373494
      WBVar00754385
      WBVar00373495
      WBVar00754386
      WBVar00373496
      WBVar00754387
      WBVar00373497
      WBVar00373498
      WBVar00754388
      WBVar01438980
      WBVar00373499
      WBVar01438981
      WBVar00754389
      WBVar00373500
      WBVar02033455
      WBVar01438982
      WBVar00754390
      WBVar02033456
      WBVar00754391
      WBVar00373501
      WBVar01438985
      WBVar00754392
      WBVar00373502
      WBVar00754393
      WBVar00373503
      WBVar00754394
      WBVar00373504
      WBVar00373505
      WBVar00754395
      WBVar00373506
      WBVar00754396
      WBVar00373507
      WBVar00754397
      WBVar00754398
      WBVar00754399
      WBVar00754400
      WBVar02109790
      WBVar00754401
      WBVar00754402
      WBVar00754403
      WBVar01499017
      WBVar00754404
      WBVar00754405
      WBVar00754406
      WBVar01801885
      WBVar00754407
      WBVar00754408
      WBVar00754409
      WBVar01242914
      WBVar00754410
      WBVar01242917
      WBVar00754411
      WBVar00754412
      WBVar01784319
      WBVar00754413
      WBVar00754414
      WBVar01242920
      WBVar01784320
      WBVar01242922
      WBVar00754415
      WBVar00754416
      WBVar01242925
      WBVar00754417
      WBVar01393940
      WBVar00105261
      WBVar01242932
      WBVar00754418
      WBVar00105262
      WBVar00754419
      WBVar01242934
      WBVar00105263
      WBVar00754420
      WBVar01242936
      WBVar00754421
      WBVar00754422
      WBVar00754423
      WBVar01559646
      WBVar00754424
      WBVar00754425
      WBVar00754426
      WBVar02130446
      WBVar02130447
      WBVar01377089
      WBVar01309124
      WBVar01377100
      WBVar01309125
      WBVar00234762
      WBVar01309128
      WBVar01377111
      WBVar01309130
      WBVar00238445
      WBVar01309131
      WBVar00238446
      WBVar01309132
      WBVar01377122
      WBVar01309133
      WBVar01377133
      WBVar01309134
      WBVar00145919
      WBVar01538367
      WBVar01309136
      WBVar01538368
      WBVar02018099
      WBVar01538369
      WBVar01309140
      WBVar01538370
      WBVar01309142
      WBVar01826611
      WBVar01309143
      WBVar00145925
      WBVar01309149
      WBVar01309151
      WBVar01309155
      WBVar02002901
      WBVar01309156
      WBVar01309157
      WBVar02002902
      WBVar01831283
      WBVar01252617
      WBVar00142355
      WBVar01252628
      WBVar01252639
      WBVar00754291
      WBVar00754292
      WBVar00754293
      WBVar00754294
      WBVar00754295
      WBVar00754296
      WBVar00754297
      WBVar00754298
      WBVar00754299
      WBVar00754300
      WBVar00754301
      WBVar00754302
      WBVar00754303
      WBVar00754304
      WBVar00754305
      WBVar01400232
      WBVar00754306
      WBVar00754307
      WBVar01685355
      WBVar00754308
      WBVar00754309
      WBVar00754310
      WBVar01666373
      WBVar00754311
      WBVar01666374
      WBVar00754312
      WBVar00754313
      WBVar01666375
      WBVar02086334
      WBVar00754314
      WBVar01666376
      WBVar01666377
      WBVar00754315
      WBVar00754316
      WBVar01666378
      WBVar00754317
      WBVar00754318
      WBVar00754319
      WBVar00266059
      WBVar00754320
      WBVar00754321
      WBVar00754322
      WBVar00754323
      WBVar00754324
      WBVar00754325
      WBVar01498940
      WBVar00754326
      WBVar00754327
      WBVar01935179
      WBVar00602423
      WBVar01935182
      WBVar01496365
      WBVar00754328
      WBVar02151770
      WBVar00754329
      WBVar00754330
      WBVar00754331
      WBVar01696088
      WBVar01696089
      WBVar00754332
      WBVar01696090
      WBVar00754333
      WBVar00754334
      WBVar00754335
      WBVar01720446
      WBVar01720447
      WBVar00754336
      WBVar01720448
      WBVar00754337
      WBVar01413720
      WBVar00174427
      WBVar00754338
      WBVar00174428
      WBVar00754339
      WBVar00754340
      WBVar00174429
      WBVar00174430
      WBVar00754341
      WBVar00174431
      WBVar00754342
      WBVar00174432
      WBVar00754343
      WBVar01982600
      WBVar00174433
      WBVar00754344
      WBVar00754345
      WBVar00174434
      WBVar00754346
      WBVar00174435
      WBVar00227675
      WBVar00754347
      WBVar00227676
      WBVar00174436
      WBVar00754348
      WBVar00174437
      WBVar00227677
      WBVar00227678
      WBVar00754349
      WBVar00174438
    Strain: WBStrain00036395
      WBStrain00036410
    RNASeq_FPKM (74)
    GO_annotation (28)
    Contained_in_operon: CEOP2709
    Ortholog (31)
    Structured_description: Concise_description: jun-1 encodes a basic-leucine zipper (bZIP) transcription factor that is the C. elegans JUN homolog; jun-1 activity is essential for regulation of ovulation, and thus normal levels of fertility; in regulating ovulation, JUN-1 functions with FOS-1 to regulate expression of plc-1 which encodes a phospholipase C essential for IP3 production and ovulation; in addition, JUN-1 interacts with FOS-1 in vitro to form heterodimers capable of binding upstream regulatory sequences of egl-13, which encodes a transcription factor required for uterine cell fate specification; jun-1 is expressed in the uterus and the spermatheca. Paper_evidence: WBPaper00031111
            WBPaper00034689
          Curator_confirmed: WBPerson1843
          Date_last_updated: 19 Jan 2010 00:00:00
      Automated_description: Enables RNA polymerase II-specific DNA-binding transcription factor binding activity and sequence-specific DNA binding activity. Involved in several processes, including determination of adult lifespan; positive regulation of RNA splicing; and response to starvation. Located in nucleus. Expressed in several structures, including excretory cell; hermaphrodite gonad; nervous system; pharyngeal-intestinal valve; and pharynx. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); gastrointestinal system cancer (multiple); and lymphoma (multiple). Is an ortholog of human JUN (Jun proto-oncogene, AP-1 transcription factor subunit); JUNB (JunB proto-oncogene, AP-1 transcription factor subunit); and JUND (JunD proto-oncogene, AP-1 transcription factor subunit). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model (22)
  Molecular_info: Corresponding_CDS: T24H10.7a
      T24H10.7b
      T24H10.7c
      T24H10.7d
      T24H10.7e
      T24H10.7f
      T24H10.7g
      T24H10.7h
      T24H10.7i
    Corresponding_CDS_history: T24H10.7:wp136
    Corresponding_transcript: T24H10.7a.1
      T24H10.7b.1
      T24H10.7c.1
      T24H10.7d.1
      T24H10.7e.1
      T24H10.7f.1
      T24H10.7g.1
      T24H10.7h.1
      T24H10.7i.1
    Other_sequence (42)
    Associated_feature (34)
    Gene_product_binds (375)
    Transcription_factor: WBTranscriptionFactor000109
      WBTranscriptionFactor000501
  Experimental_info: RNAi_result (33)
    Expr_pattern (14)
    Drives_construct: WBCnstr00012826
      WBCnstr00014260
      WBCnstr00014283
      WBCnstr00014284
      WBCnstr00014288
      WBCnstr00014300
      WBCnstr00014302
      WBCnstr00030207
    Construct_product: WBCnstr00030207
    Microarray_results (48)
    Expression_cluster (184)
    Interaction (46)
  Map_info: Map: II Position: 1.04759 Error: 0.001496
    Positive: Positive_clone: T24H10 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (24)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene