WormBase Tree Display for Gene: WBGene00011904
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| WBGene00011904 | SMap | S_parent | Sequence | T21H8 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | hlb-1 | Paper_evidence | WBPaper00033002 | |||||
| Sequence_name | T21H8.1 | ||||||||
| Molecular_name (58) | |||||||||
| Other_name | CELE_T21H8.1 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | hlb-1 | ||||||||
| DB_info | Database | AceView | gene | XO484 | |||||
| WormQTL | gene | WBGene00011904 | |||||||
| WormFlux | gene | WBGene00011904 | |||||||
| NDB | locus_tag | CELE_T21H8.1 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00011904|UniProtKB=Q94071 | |||||||
| family | PTHR12587 | ||||||||
| NCBI | gene | 181499 | |||||||
| RefSeq | protein (19) | ||||||||
| SwissProt | UniProtAcc | Q94071 | |||||||
| UniProt_GCRP | UniProtAcc | Q94071 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:53 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 23 Apr 2010 11:09:26 | WBPerson2970 | Name_change | CGC_name | hlb-1 | ||||
| 3 | 18 Feb 2016 15:51:46 | WBPerson1983 | Event | Acquires_merge | WBGene00011905 | ||||
| Acquires_merge | WBGene00011905 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | hlb | ||||||||
| Allele (327) | |||||||||
| Strain | WBStrain00031591 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00086974 | ||||||||
| 00086975 | |||||||||
| 00086976 | |||||||||
| 00086977 | |||||||||
| 00086978 | |||||||||
| 00086979 | |||||||||
| Ortholog (43) | |||||||||
| Paralog | WBGene00006364 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | hlb-1 encodes the C. elegans ortholog of human beta-liprin, a coiled-coil domain-containing protein that interacts with alpha-liprin, a transmembrane protein-tyrosine phosphatase-interacting protein; hlb-1 functions cell non-autonomously in the organization and proper function of neuromuscular junctions and hence, is also required for wild type locomotory behavior; an hlb-1 reporter fusion construct directs expression in pharyngeal and body wall muscles, and in regions adjacent to the dorsal and ventral nerve cords; expression in the pharynx is particularly strong in the posterior bulb. | Paper_evidence | WBPaper00003493 | |||||
| WBPaper00004651 | |||||||||
| WBPaper00005654 | |||||||||
| WBPaper00025054 | |||||||||
| WBPaper00030810 | |||||||||
| WBPaper00033002 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 23 Apr 2010 00:00:00 | ||||||||
| Automated_description | Involved in several processes, including neuromuscular junction development; positive regulation of locomotion; and regulation of pharyngeal pumping. Predicted to be located in presynaptic active zone. Is an ortholog of human PPFIBP1 (PPFIA binding protein 1) and PPFIBP2 (PPFIA binding protein 2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS (19) | ||||||||
| Corresponding_CDS_history | T21H8.1:wp131 | ||||||||
| T21H8.1:wp178 | |||||||||
| Corresponding_transcript (20) | |||||||||
| Other_sequence (35) | |||||||||
| Associated_feature (21) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00035776 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00053770 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00018991 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00001136 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00053766 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr2088 | ||||||||
| Expr1011344 | |||||||||
| Expr1025976 | |||||||||
| Expr1035250 | |||||||||
| Expr1035251 | |||||||||
| Expr1157316 | |||||||||
| Expr1157320 | |||||||||
| Expr2012489 | |||||||||
| Expr2030728 | |||||||||
| Drives_construct | WBCnstr00030295 | ||||||||
| WBCnstr00030296 | |||||||||
| Construct_product | WBCnstr00030295 | ||||||||
| WBCnstr00030296 | |||||||||
| Microarray_results (42) | |||||||||
| Expression_cluster (161) | |||||||||
| Interaction (44) | |||||||||
| Map_info | Map | X | Position | 15.0875 | |||||
| Positive | Positive_clone | T21H8 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00003493 | ||||||||
| WBPaper00030810 | |||||||||
| WBPaper00031717 | |||||||||
| WBPaper00033002 | |||||||||
| WBPaper00035492 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00064473 | |||||||||
| WBPaper00064480 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| [140923 pad] Modified Map position as it was a reverse physical that could not be fixed by automated methods. | |||||||||
| Method | Gene |
