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WormBase Tree Display for Gene: WBGene00011767

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Name Class

WBGene00011767SMapS_parentSequenceT14D7
IdentityVersion2
NameCGC_nameagxt-1Person_evidenceWBPerson17942
Sequence_nameT14D7.1
Molecular_nameT14D7.1
T14D7.1.1
CE23985
T14D7.1.2
Other_nameCELE_T14D7.1Accession_evidenceNDBBX284602
Public_nameagxt-1
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:53WBPerson1971EventImportedInitial conversion from CDS class of WS125
204 Sep 2015 11:19:37WBPerson2970Name_changeCGC_nameagxt-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classagxt
Allele (50)
StrainWBStrain00003009
RNASeq_FPKM (74)
GO_annotation00086956
00086957
00086958
00086959
00086960
00086961
00086962
00086963
00086964
00086965
Ortholog (34)
ParalogWBGene00009177Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionT14D7.1 is orthologous to the human gene ALANINE-GLYOXYLATE AMINOTRANSFERASE HOMOLOG (AGXT; OMIM:604285), which when mutated leads to disease.Paper_evidenceWBPaper00004637
Curator_confirmedWBPerson1823
WBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionEnables alanine-glyoxylate transaminase activity. Involved in glycine biosynthetic process, by transamination of glyoxylate. Located in mitochondrion. Human ortholog(s) of this gene implicated in primary hyperoxaluria type 1. Is an ortholog of human AGXT (alanine--glyoxylate aminotransferase).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0111670Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:341)
Molecular_infoCorresponding_CDST14D7.1
Corresponding_transcriptT14D7.1.1
T14D7.1.2
Other_sequence (102)
Associated_featureWBsf658006
WBsf658007
WBsf658008
WBsf658009
WBsf988838
WBsf221823
WBsf221824
Experimental_infoRNAi_resultWBRNAi00053319Inferred_automaticallyRNAi_primary
WBRNAi00035565Inferred_automaticallyRNAi_primary
WBRNAi00018708Inferred_automaticallyRNAi_primary
Expr_patternChronogram797
Expr6693
Expr15739
Expr1015563
Expr1035181
Expr1156904
Expr2009267
Expr2027504
Drives_constructWBCnstr00003509
Microarray_results (19)
Expression_clusterWBPaper00029359_1280
WBPaper00029359_1304
WBPaper00029359_1325
WBPaper00029359_1444
WBPaper00029359_1497
WBPaper00029359_1504
WBPaper00029359_1604
WBPaper00029359_1629
WBPaper00031040:TGF-beta_adult_upregulated
WBPaper00035073:mitochondria_protein
WBPaper00035211:age-1_vs_N2_downregulated
WBPaper00036375:enriched_in_PVD_OLL
WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
WBPaper00037950:hypodermis_L3-L4-larva_expressed
WBPaper00037950:intestine_embryo_enriched
WBPaper00037950:intestine_embryo_SelectivelyEnriched
WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
WBPaper00042561:smgl-1(RNAi)_upregulated
WBPaper00044736:flat_dev_expression
WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
WBPaper00045417:128Q-huntingtin_upreglated
WBPaper00045521:Spermatogenic
WBPaper00046509:htz-1(ok3099)_upregulated
WBPaper00048923:Aging_regulated
WBPaper00048988:neuron_expressed
WBPaper00049545:jmjd-3.1(+)_downregulated
WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
WBPaper00050488:mir-34(OverExpression)_vs_N2_regulated_adult_20C
WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_adult_25C
WBPaper00050726:OsmoticStress_regulated_Food
WBPaper00050726:OsmoticStress_regulated_NoFood
WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
WBPaper00050990:hypodermis_expressed
WBPaper00050990:intestine_expressed
WBPaper00050990:NMDA-neuron_expressed
WBPaper00051404:alg-1(gk214)_downregulated
WBPaper00051558:aging_regulated
WBPaper00052884:emb-4(hc60)_upregulated
WBPaper00053184:sma-4(rax3)_upregulated
WBPaper00053302:stavudine_24h_regulated
WBPaper00053308:SMG-2_associated_NMD(-)_unaltered_ClassII
WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_fed-L1_Truseq
WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_starved-L1_Truseq
WBPaper00053388:dauer_regulated_Cluster5
WBPaper00053599:female_vs_male_downregulated
WBPaper00053599:oocyte_vs_mitosis_downregulated
WBPaper00055354:Rapamycin-Rifampicin-Allantoin_upregulated
WBPaper00055354:Rapamycin-Rifampicin-Psora_upregulated
WBPaper00055354:Rapamycin-Rifampicin_upregulated
WBPaper00055482:pmt-2(RNAi)_upregulated
WBPaper00055626:pry-1(mu38)_downregulated
WBPaper00055648:sperm_expressed
WBPaper00055804:FBF-1-FBF-2-associated_spermatogenic-enriched
WBPaper00056034:pals-22(jy3)_upregulated
WBPaper00056034:pals-25(jy9)_upregulated
WBPaper00056161:male_enriched_siRNA
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
WBPaper00056471:S.aureus-4h_downregulated_N2
WBPaper00056809:smn-1(ok355)_downregulated
WBPaper00057154:HeatShock_upregulated_mRNA
WBPaper00057288:iff-1(RNAi)_downregulated_transcript
WBPaper00058598:sin-3(tm1276)_downregulated
WBPaper00058691:sin-3(tm1276)_downregulated
WBPaper00059253:sucrose_stearic-acid_upregulated
WBPaper00059253:sucrose_upregulated
WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
WBPaper00060014:set-2(tm1630)_downregulated
WBPaper00060811:L1_vs_adult_downregulated_neural
WBPaper00061007:HB101_upregulated
WBPaper00061007:S.aquatilis_upregulated
WBPaper00061203:sin-3(tm1276)_upregulated
WBPaper00061340:BWM_anterior
WBPaper00061340:BWM_far_posterior
WBPaper00061341:28C_48h_downregulated
WBPaper00061527:C18B2.5-haf-4_181
WBPaper00062159:hda-2(ok1479)_upregulated
WBPaper00062325:muscle_enriched_coding-RNA
WBPaper00062669:extracellular-vesicle_protein
WBPaper00064071:NHR-49_interacting
WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
WBPaper00064229:B.thuringiensis-Cry5Ba_upregulated
WBPaper00064315:mes-3(bn199)_upregulated_PGCs
WBPaper00064502:nhr-23(kry61);spe-44(fx110)_downregulated
WBPaper00064502:spe-44(fx110)_downregulated
WBPaper00064716:paraquat_downregulated
WBPaper00064871:hypoxia_downregulated_F2
WBPaper00065096:25C_vs_20C_downregulated
WBPaper00065096:Day10_vs_Day1_downregulated
WBPaper00065373:Cisplatin_downregulated_WT
WBPaper00065993:glp-1(e2141)_upregulated
WBPaper00066085:hda-3(ok1991)_upregulated
WBPaper00066110:Doxorubicin_upregulated_diploid
WBPaper00066110:tetraploid_vs_diploid_upregulated
cgc4489_group_24
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00026980:intestine_enriched
WBPaper00028948:cep-1(gk138)+UV_downregulated
WBPaper00031003:0hr_muscle_enriched
WBPaper00031003:24hr_muscle_enriched
WBPaper00031003:hlh_1_enriched
WBPaper00031003:total_muscle_enriched
WBPaper00032062:age_regulated_genes
WBPaper00035588:alg-1(-)_upregulated
WBPaper00035873:dpy-9_regulated
WBPaper00035873:dpy-10_regulated
WBPaper00036286:Pattern_G
WBPaper00037695:LD_3-day
WBPaper00037695:WC_CC_6-day
WBPaper00038172:tax-6null_down_regulated
WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
WBPaper00040963:TA300_up
WBPaper00041606:CE_X.nematophila_regulated
WBPaper00041939:EtBr-exposed_vs_UVC-exposed_51h
WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
WBPaper00045263:nuo-6(qm200)_upregulated
WBPaper00047070:N2_starvation_downregulated
WBPaper00048637:lin-35(n745)_starvation_downregulated
WBPaper00048989:eat-2(ad465)_rapamycin_downregulated
WBPaper00053236:Starvation_regulated_N2
[cgc5767]:expression_class_E
[cgc5767]:expression_class_E_pi(186_min)
[cgc5767]:expression_class_M
[cgc5767]:expression_class_ME
[cgc6390]:Cluster_D
[cgc6390]:mixed_spermatogenesis-somatic
Interaction (24)
Map_infoMapIIPosition0.905429
PositivePositive_cloneT14D7Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00038491
WBPaper00049683
WBPaper00055090
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene