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WormBase Tree Display for Gene: WBGene00011590

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Name Class

WBGene00011590SMapS_parentSequenceT07F10
IdentityVersion2
NameCGC_namebus-19Paper_evidenceWBPaper00028877
Person_evidenceWBPerson261
Sequence_nameT07F10.4
Molecular_nameT07F10.4a
T07F10.4a.1
CE36194
T07F10.4b
Other_nameCELE_T07F10.4Accession_evidenceNDBBX284605
Public_namebus-19
DB_infoDatabaseWormQTLgeneWBGene00011590
WormFluxgeneWBGene00011590
NDBlocus_tagCELE_T07F10.4
PanthergeneCAEEL|WormBase=WBGene00011590|UniProtKB=Q22316
familyPTHR43220
NCBIgene179766
RefSeqproteinNM_001047697.5
NR_003174.1
TREEFAMTREEFAM_IDTF314301
TrEMBLUniProtAccQ22316
UniProt_GCRPUniProtAccQ22316
RNAcentralURSidURS0000511154
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:52WBPerson1971EventImportedInitial conversion from CDS class of WS125
201 Feb 2007 10:30:33WBPerson2970Name_changeCGC_namebus-19
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classbus
Allele (162)
StrainWBStrain00004692
WBStrain00004699
WBStrain00004700
RNASeq_FPKM (74)
GO_annotation00074886
00074887
Ortholog (33)
ParalogWBGene00006520Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00013513Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
Structured_descriptionConcise_descriptionbus-19 encodes an ancient but unfamiliar transmembrane protein required for colonization by Microbacterium nematophilum and the tail-swelling response to M. nematophilum infection, as well as for cuticle integrity and traction during movement, normal alae and body shape, dauer formation, normally rapid growth, and larval viability; BUS-19 (along with Y71A12C.2) is orthologous to human TMEM41A, and paralogous to TAG-175/D2013.10 and human TMEM41B; both BUS-19 and TAG-175 are orthologous to plant and fungal proteins such as budding yeast Tvp38p, and bacterial proteins such as Geobacter metallireducens DedA; given its orthology with Tvp38p, BUS-19 may colocalize to late Golgi vesicles with the Tlg2p ortholog SYN-16 and with a variety of other protein ligands.Paper_evidenceWBPaper00028877
WBPaper00030783
WBPaper00030784
WBPaper00030785
Curator_confirmedWBPerson567
Date_last_updated17 Jul 2007 00:00:00
Automated_descriptionPredicted to be located in membrane. Is an ortholog of human TMEM41A (transmembrane protein 41A).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDST07F10.4a
Corresponding_CDS_historyT07F10.4:wp114
Corresponding_transcriptT07F10.4b
T07F10.4a.1
Other_sequence (20)
Associated_feature (18)
Experimental_infoRNAi_resultWBRNAi00052771Inferred_automaticallyRNAi_primary
WBRNAi00035312Inferred_automaticallyRNAi_primary
WBRNAi00090769Inferred_automaticallyRNAi_primary
WBRNAi00090768Inferred_automaticallyRNAi_primary
Expr_patternExpr1018972
Expr1035108
Expr1156378
Expr2009686
Expr2027925
Drives_constructWBCnstr00030536
Construct_productWBCnstr00030536
Microarray_results (25)
Expression_cluster (211)
Interaction (49)
Map_infoMapVPosition4.72059
PositivePositive_cloneT07F10Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00028877
WBPaper00038491
WBPaper00052104
WBPaper00055090
WBPaper00058949
WBPaper00062563
WBPaper00063192
WBPaper00065106
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
[140923 pad] Modified Map position as it was a reverse physical that could not be fixed by automated methods.
MethodGene