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WormBase Tree Display for Gene: WBGene00011590

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Name Class

WBGene00011590SMapS_parentSequenceT07F10
IdentityVersion2
NameCGC_namebus-19Paper_evidenceWBPaper00028877
Person_evidenceWBPerson261
Sequence_nameT07F10.4
Molecular_nameT07F10.4a
T07F10.4a.1
CE36194
T07F10.4b
Other_nameCELE_T07F10.4Accession_evidenceNDBBX284605
Public_namebus-19
DB_infoDatabaseWormQTLgeneWBGene00011590
WormFluxgeneWBGene00011590
NDBlocus_tagCELE_T07F10.4
PanthergeneCAEEL|WormBase=WBGene00011590|UniProtKB=Q22316
familyPTHR43220
NCBIgene179766
RefSeqproteinNM_001047697.5
NR_003174.1
TREEFAMTREEFAM_IDTF314301
TrEMBLUniProtAccQ22316
UniProt_GCRPUniProtAccQ22316
RNAcentralURSidURS0000511154
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:52WBPerson1971EventImportedInitial conversion from CDS class of WS125
201 Feb 2007 10:30:33WBPerson2970Name_changeCGC_namebus-19
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classbus
Allele (162)
StrainWBStrain00004692
WBStrain00004699
WBStrain00004700
RNASeq_FPKM (74)
GO_annotation00074886
00074887
Ortholog (33)
ParalogWBGene00006520Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00013513Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
Structured_descriptionConcise_descriptionbus-19 encodes an ancient but unfamiliar transmembrane protein required for colonization by Microbacterium nematophilum and the tail-swelling response to M. nematophilum infection, as well as for cuticle integrity and traction during movement, normal alae and body shape, dauer formation, normally rapid growth, and larval viability; BUS-19 (along with Y71A12C.2) is orthologous to human TMEM41A, and paralogous to TAG-175/D2013.10 and human TMEM41B; both BUS-19 and TAG-175 are orthologous to plant and fungal proteins such as budding yeast Tvp38p, and bacterial proteins such as Geobacter metallireducens DedA; given its orthology with Tvp38p, BUS-19 may colocalize to late Golgi vesicles with the Tlg2p ortholog SYN-16 and with a variety of other protein ligands.Paper_evidenceWBPaper00028877
WBPaper00030783
WBPaper00030784
WBPaper00030785
Curator_confirmedWBPerson567
Date_last_updated17 Jul 2007 00:00:00
Automated_descriptionPredicted to be located in membrane. Is an ortholog of human TMEM41A (transmembrane protein 41A).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDST07F10.4a
Corresponding_CDS_historyT07F10.4:wp114
Corresponding_transcriptT07F10.4b
T07F10.4a.1
Other_sequence (20)
Associated_feature (18)
Experimental_infoRNAi_resultWBRNAi00052771Inferred_automaticallyRNAi_primary
WBRNAi00035312Inferred_automaticallyRNAi_primary
WBRNAi00090769Inferred_automaticallyRNAi_primary
WBRNAi00090768Inferred_automaticallyRNAi_primary
Expr_patternExpr1018972
Expr1035108
Expr1156378
Expr2009686
Expr2027925
Drives_constructWBCnstr00030536
Construct_productWBCnstr00030536
Microarray_results (25)
Expression_cluster (211)
Interaction (49)
Map_infoMapVPosition4.72059
PositivePositive_cloneT07F10Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (8)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
[140923 pad] Modified Map position as it was a reverse physical that could not be fixed by automated methods.
MethodGene