WormBase Tree Display for Gene: WBGene00011232
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WBGene00011232 | SMap | S_parent | Sequence | R11A5 | ||
---|---|---|---|---|---|---|
Identity (6) | ||||||
Gene_info | Biotype | SO:0001217 | ||||
Gene_class | pck | |||||
Allele (66) | ||||||
Possibly_affected_by | WBVar02153165 | |||||
Strain | WBStrain00002263 | |||||
WBStrain00032650 | ||||||
WBStrain00049322 | ||||||
RNASeq_FPKM (74) | ||||||
GO_annotation (22) | ||||||
Ortholog (45) | ||||||
Paralog | WBGene00021043 | Caenorhabditis elegans | From_analysis | Panther | ||
WormBase-Compara | ||||||
WBGene00019151 | Caenorhabditis elegans | From_analysis | Panther | |||
WormBase-Compara | ||||||
Structured_description | Concise_description | pck-2 is one of three C. elegans genes that encode proteins with similarity to phosphoenolpyruvate carboxykinase (PEPCK); by similarity, the products of pck-2 are predicted to function in gluconeogenesis. | Curator_confirmed | WBPerson1843 | ||
Date_last_updated | 02 Aug 2011 00:00:00 | |||||
Automated_description | Predicted to enable manganese ion binding activity and phosphoenolpyruvate carboxykinase (GTP) activity. Predicted to be involved in several processes, including carbohydrate biosynthetic process; cellular response to oxygen-containing compound; and propionate catabolic process. Predicted to be located in cytosol and mitochondrion. Expressed in several structures, including body wall musculature; hypodermis; muscle cell; pharynx; and in male. Human ortholog(s) of this gene implicated in Alzheimer's disease and type 2 diabetes mellitus. Is an ortholog of human PCK1 (phosphoenolpyruvate carboxykinase 1). | Paper_evidence | WBPaper00065943 | |||
Curator_confirmed | WBPerson324 | |||||
WBPerson37462 | ||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | |||||
Date_last_updated | 29 Nov 2023 00:00:00 | |||||
Disease_info | Potential_model | DOID:10652 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:8724) | |
DOID:9352 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:8724) | |||
Molecular_info | Corresponding_CDS | R11A5.4a | ||||
R11A5.4b | ||||||
R11A5.4c | ||||||
R11A5.4d | ||||||
Corresponding_CDS_history | R11A5.4b:wp274 | |||||
Corresponding_transcript | R11A5.4a.1 | |||||
R11A5.4a.2 | ||||||
R11A5.4b.1 | ||||||
R11A5.4c.1 | ||||||
R11A5.4d.1 | ||||||
Other_sequence (359) | ||||||
Associated_feature (19) | ||||||
Experimental_info | RNAi_result | WBRNAi00116976 | Inferred_automatically | RNAi_primary | ||
WBRNAi00051760 | Inferred_automatically | RNAi_primary | ||||
WBRNAi00077181 | Inferred_automatically | RNAi_primary | ||||
WBRNAi00090555 | Inferred_automatically | RNAi_primary | ||||
WBRNAi00034849 | Inferred_automatically | RNAi_primary | ||||
WBRNAi00001222 | Inferred_automatically | RNAi_primary | ||||
WBRNAi00051759 | Inferred_automatically | RNAi_primary | ||||
WBRNAi00004079 | Inferred_automatically | RNAi_primary | ||||
Expr_pattern (16) | ||||||
Drives_construct | WBCnstr00002285 | |||||
WBCnstr00004292 | ||||||
WBCnstr00004926 | ||||||
WBCnstr00011844 | ||||||
WBCnstr00030823 | ||||||
WBCnstr00042040 | ||||||
WBCnstr00042041 | ||||||
Construct_product | WBCnstr00030823 | |||||
WBCnstr00042040 | ||||||
Microarray_results (41) | ||||||
Expression_cluster (246) | ||||||
Interaction (47) | ||||||
Map_info | Map | I | Position | 2.38327 | ||
Positive | Positive_clone | R11A5 | Inferred_automatically | From sequence, transcript, pseudogene data | ||
Pseudo_map_position | ||||||
Reference (22) | ||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||
[200811 gw3] Modified Map position as it was a reverse physical that could not be fixed by automated methods. (2.36373) | ||||||
Method | Gene |