WormBase Tree Display for Gene: WBGene00021043
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| WBGene00021043 | SMap | S_parent | Sequence | W05G11 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | pck-1 | Person_evidence | WBPerson2192 | |||||
| Sequence_name | W05G11.6 | ||||||||
| Molecular_name | W05G11.6 | ||||||||
| W05G11.6.1 | |||||||||
| CE19610 | |||||||||
| Other_name | CELE_W05G11.6 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | pck-1 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:31:04 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 17 Feb 2012 16:57:01 | WBPerson2970 | Name_change | CGC_name | pck-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | pck | ||||||||
| Allele (218) | |||||||||
| Strain | WBStrain00032381 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (24) | |||||||||
| Ortholog (41) | |||||||||
| Paralog | WBGene00011232 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00019151 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | pck-1 is one of three C. elegans genes that encode proteins with similarity to phosphoenolpyruvate carboxykinase (PEPCK); by similarity, the products of W05G11.6 are predicted to function in gluconeogenesis. | Curator_confirmed | WBPerson1843 | |||||
| Date_last_updated | 27 Jul 2012 00:00:00 | ||||||||
| Automated_description | Predicted to enable manganese ion binding activity and phosphoenolpyruvate carboxykinase (GTP) activity. Predicted to be involved in several processes, including carbohydrate biosynthetic process; cellular response to oxygen-containing compound; and propionate catabolic process. Located in cytosol and striated muscle dense body. Expressed in several structures, including body wall musculature; preanal ganglion; somatic nervous system; tail ganglion; and in male. Human ortholog(s) of this gene implicated in Alzheimer's disease and type 2 diabetes mellitus. Is an ortholog of human PCK1 (phosphoenolpyruvate carboxykinase 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:10652 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:8724) | ||||
| DOID:9352 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:8724) | ||||||
| Molecular_info | Corresponding_CDS | W05G11.6 | |||||||
| Corresponding_CDS_history | W05G11.6b:wp275 | ||||||||
| W05G11.6d:wp275 | |||||||||
| Corresponding_transcript | W05G11.6.1 | ||||||||
| Other_sequence (167) | |||||||||
| Associated_feature (15) | |||||||||
| Experimental_info | RNAi_result (13) | ||||||||
| Expr_pattern | Expr9397 | ||||||||
| Expr15024 | |||||||||
| Expr15026 | |||||||||
| Expr1024494 | |||||||||
| Expr1039172 | |||||||||
| Expr1158379 | |||||||||
| Expr2014778 | |||||||||
| Expr2033012 | |||||||||
| Drives_construct | WBCnstr00041522 | ||||||||
| WBCnstr00041875 | |||||||||
| WBCnstr00041876 | |||||||||
| Construct_product | WBCnstr00013962 | ||||||||
| WBCnstr00041876 | |||||||||
| WBCnstr00042950 | |||||||||
| WBCnstr00042951 | |||||||||
| Microarray_results (39) | |||||||||
| Expression_cluster (317) | |||||||||
| Interaction (47) | |||||||||
| Map_info | Map | III | Position | -27.1341 | |||||
| Positive | Positive_clone | W05G11 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (16) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
