WormBase Tree Display for Gene: WBGene00011232
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| WBGene00011232 | SMap | S_parent | Sequence | R11A5 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | pck-2 | Person_evidence | WBPerson2192 | |||||
| Sequence_name | R11A5.4 | ||||||||
| Molecular_name (13) | |||||||||
| Other_name | CELE_R11A5.4 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | pck-2 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:52 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 17 Feb 2012 16:57:01 | WBPerson2970 | Name_change | CGC_name | pck-2 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | pck | ||||||||
| Allele (66) | |||||||||
| Possibly_affected_by | WBVar02153165 | ||||||||
| Strain | WBStrain00002263 | ||||||||
| WBStrain00032650 | |||||||||
| WBStrain00049322 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (22) | |||||||||
| Ortholog (45) | |||||||||
| Paralog | WBGene00021043 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00019151 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | pck-2 is one of three C. elegans genes that encode proteins with similarity to phosphoenolpyruvate carboxykinase (PEPCK); by similarity, the products of pck-2 are predicted to function in gluconeogenesis. | Curator_confirmed | WBPerson1843 | |||||
| Date_last_updated | 02 Aug 2011 00:00:00 | ||||||||
| Automated_description | Predicted to enable manganese ion binding activity and phosphoenolpyruvate carboxykinase (GTP) activity. Predicted to be involved in several processes, including carbohydrate biosynthetic process; cellular response to oxygen-containing compound; and propionate catabolic process. Predicted to be located in cytosol and mitochondrion. Expressed in several structures, including body wall musculature; hypodermis; muscle cell; pharynx; and in male. Human ortholog(s) of this gene implicated in Alzheimer's disease and type 2 diabetes mellitus. Is an ortholog of human PCK1 (phosphoenolpyruvate carboxykinase 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:10652 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:8724) | ||||
| DOID:9352 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:8724) | ||||||
| Molecular_info | Corresponding_CDS | R11A5.4a | |||||||
| R11A5.4b | |||||||||
| R11A5.4c | |||||||||
| R11A5.4d | |||||||||
| Corresponding_CDS_history | R11A5.4b:wp274 | ||||||||
| Corresponding_transcript | R11A5.4a.1 | ||||||||
| R11A5.4a.2 | |||||||||
| R11A5.4b.1 | |||||||||
| R11A5.4c.1 | |||||||||
| R11A5.4d.1 | |||||||||
| Other_sequence (359) | |||||||||
| Associated_feature (19) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00116976 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00051760 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00077181 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00090555 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00034849 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00001222 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00051759 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00004079 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern (16) | |||||||||
| Drives_construct | WBCnstr00002285 | ||||||||
| WBCnstr00004292 | |||||||||
| WBCnstr00004926 | |||||||||
| WBCnstr00011844 | |||||||||
| WBCnstr00030823 | |||||||||
| WBCnstr00042040 | |||||||||
| WBCnstr00042041 | |||||||||
| Construct_product | WBCnstr00030823 | ||||||||
| WBCnstr00042040 | |||||||||
| Microarray_results (41) | |||||||||
| Expression_cluster (246) | |||||||||
| Interaction | WBInteraction000140542 | ||||||||
| WBInteraction000154385 | |||||||||
| WBInteraction000155656 | |||||||||
| WBInteraction000270946 | |||||||||
| WBInteraction000273247 | |||||||||
| WBInteraction000278495 | |||||||||
| WBInteraction000355843 | |||||||||
| WBInteraction000366282 | |||||||||
| WBInteraction000390083 | |||||||||
| WBInteraction000392597 | |||||||||
| WBInteraction000398036 | |||||||||
| WBInteraction000401306 | |||||||||
| WBInteraction000401308 | |||||||||
| WBInteraction000401309 | |||||||||
| WBInteraction000406820 | |||||||||
| WBInteraction000421856 | |||||||||
| WBInteraction000421859 | |||||||||
| WBInteraction000421862 | |||||||||
| WBInteraction000421864 | |||||||||
| WBInteraction000463053 | |||||||||
| WBInteraction000465777 | |||||||||
| WBInteraction000474011 | |||||||||
| WBInteraction000474137 | |||||||||
| WBInteraction000503557 | |||||||||
| WBInteraction000544639 | |||||||||
| WBInteraction000549549 | |||||||||
| WBInteraction000550026 | |||||||||
| WBInteraction000552828 | |||||||||
| WBInteraction000553872 | |||||||||
| WBInteraction000554100 | |||||||||
| WBInteraction000561881 | |||||||||
| WBInteraction000562287 | |||||||||
| WBInteraction000562891 | |||||||||
| WBInteraction000564133 | |||||||||
| WBInteraction000566326 | |||||||||
| WBInteraction000566605 | |||||||||
| WBInteraction000568714 | |||||||||
| WBInteraction000569025 | |||||||||
| WBInteraction000569371 | |||||||||
| WBInteraction000570310 | |||||||||
| WBInteraction000571917 | |||||||||
| WBInteraction000574058 | |||||||||
| WBInteraction000577932 | |||||||||
| WBInteraction000579650 | |||||||||
| WBInteraction000580748 | |||||||||
| WBInteraction000584547 | |||||||||
| WBInteraction000586770 | |||||||||
| Map_info | Map | I | Position | 2.38327 | |||||
| Positive | Positive_clone | R11A5 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (22) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| [200811 gw3] Modified Map position as it was a reverse physical that could not be fixed by automated methods. (2.36373) | |||||||||
| Method | Gene |
