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WormBase Tree Display for Gene: WBGene00011181

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Name Class

WBGene00011181SMapS_parentSequenceR09H10
IdentityVersion1
NameSequence_nameR09H10.3
Molecular_nameR09H10.3a
R09H10.3a.1
CE34083
R09H10.3b
CE12662
R09H10.3b.1
Other_nameCELE_R09H10.3Accession_evidenceNDBBX284604
Public_nameR09H10.3
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:52WBPerson1971EventImportedInitial conversion from CDS class of WS125
StatusLive
Gene_infoBiotypeSO:0001217
Allele (22)
RNASeq_FPKM (74)
GO_annotation00073201
00073202
00073203
00073204
00073205
00073206
00073207
00073208
00118464
00118465
Ortholog (33)
ParalogWBGene00022808Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
Panther
WormBase-Compara
Structured_descriptionConcise_descriptionR09H10.3 is orthologous to the human gene TRANSTHYRETIN (PREALBUMIN, AMYLOIDOSIS TYPE I) (TTR; OMIM:176300), which when mutated leads to disease.Curator_confirmedWBPerson1823
WBPerson567
Date_last_updated06 Aug 2004 00:00:00
Automated_descriptionEnables identical protein binding activity. Predicted to be involved in purine nucleobase metabolic process. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; carpal tunnel syndrome 1; colorectal adenoma; and gastrointestinal system cancer (multiple). Is an ortholog of human TTR (transthyretin).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_model (13)
Molecular_infoCorresponding_CDSR09H10.3a
R09H10.3b
Corresponding_CDS_historyR09H10.3:wp101
Corresponding_transcriptR09H10.3a.1
R09H10.3b.1
Other_sequence (19)
Associated_featureWBsf646315
WBsf646316
WBsf013952
WBsf229008
Experimental_infoRNAi_resultWBRNAi00022857Inferred_automaticallyRNAi_primary
WBRNAi00034793Inferred_automaticallyRNAi_primary
WBRNAi00051648Inferred_automaticallyRNAi_primary
WBRNAi00017668Inferred_automaticallyRNAi_primary
Expr_patternExpr1010795
Expr1155319
Expr2005525
Expr2023744
Drives_constructWBCnstr00000541
WBCnstr00030868
Construct_productWBCnstr00030868
Microarray_results (25)
Expression_clusterWBPaper00031040:TGF-beta_adult_upregulated
WBPaper00032528:L3_enriched
WBPaper00035269:cde-1_regulated
WBPaper00037950:A-class-motor-neurons_L1-larva_expressed
WBPaper00037950:all-neurons_L1-larva_expressed
WBPaper00037950:AVE-neuron_L1-larva_expressed
WBPaper00037950:BAG-neuron_blastula-embryo_expressed
WBPaper00037950:bodywall-muscle_L1-larva_expressed
WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
WBPaper00037950:germline-precursors_blastula-embryo_expressed
WBPaper00037950:hypodermis_L1-larva_expressed
WBPaper00037950:intestine_CoreEnriched
WBPaper00037950:intestine_embryo_enriched
WBPaper00037950:intestine_embryo_SelectivelyEnriched
WBPaper00037950:intestine_L1-larva_expressed
WBPaper00037950:intestine_L2-larva_expressed
WBPaper00037950:intestine_larva_enriched
WBPaper00037950:intestine_larva_SelectivelyEnriched
WBPaper00037950:pharyngeal-muscle_embryo_enriched
WBPaper00037950:pharyngeal-muscle_embryo_SelectivelyEnriched
WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
WBPaper00038168:lin-15B(n744)_downregulated
WBPaper00038438:P.lumniescens_24hr_downregulated_RNAseq
WBPaper00042561:smgl-1(RNAi)_downregulated
WBPaper00044316:CH3HgCl_7.5uM_downregulated
WBPaper00044736:flat_dev_expression
WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
WBPaper00045401:N.parisii_64h_downregulated
WBPaper00045417:128Q-huntingtin_downreglated
WBPaper00045420:fertilization_upregulated_transcript
WBPaper00045521:Gender_Neutral
WBPaper00045571:germline-ablation_upregulated
WBPaper00046121:endoderm_unique
WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
WBPaper00048923:Aging_regulated
WBPaper00048926:miaserin_upregulated_adult-day10
WBPaper00048988:neuron_expressed
WBPaper00049334:CE_intestine_enriched
WBPaper00049498:npr-1(ur89)_regulated_3
WBPaper00049545:cco-1(RNAi)_downregulated
WBPaper00049545:jmjd-3.1(+)_downregulated
WBPaper00049942:HeatShock_downregulated_hsf-1(RNAi)
WBPaper00049942:hsf-1(RNAi)_downregulated
WBPaper00050080:rbr-2(tm3141)_upregulated
WBPaper00050344:ASER-neuron_enriched
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050726:OsmoticStress_regulated_Food
WBPaper00050726:OsmoticStress_regulated_NoFood
WBPaper00050859:upregulated_glh-1(gk100)_vs_control_day1-adult
WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
WBPaper00050990:arcade_intestinal-valve_expressed
WBPaper00050990:body-muscle_expressed
WBPaper00050990:hypodermis_expressed
WBPaper00050990:intestine_expressed
WBPaper00051039:intestine_enriched
WBPaper00051265:F4_morc-1(tm6048)_downregulated
WBPaper00051305:vit-2(ac3)_downregulated
WBPaper00051404:alg-1(gk214)_downregulated
WBPaper00051558:aging_regulated
WBPaper00052884:emb-4(hc60)_upregulated
WBPaper00053302:stavudine_24h_regulated
WBPaper00053302:zidovudine_24h_regulated
WBPaper00053388:dauer_regulated_Cluster4
WBPaper00053599:oocyte_vs_mitosis_downregulated
WBPaper00053606:N2_vs_elt-2(ca15);elt-7(tm840)_downregulated
WBPaper00053713:Pheromone-induced_postdauer_vs_control_downregulated
WBPaper00053713:Starvation-induced_postdauer_vs_control_upregulated
WBPaper00053792:Ochrobactrum_upregulated
WBPaper00053810:sod-2(ok1030)_downregulated
WBPaper00054758:alg-1(gk204)_downregulated
WBPaper00055049:S.gordonii_downregulated
WBPaper00055354:Psora-Allantoin_downregulated
WBPaper00055354:Rapamycin-Metformin_downregulated
WBPaper00055354:Rapamycin-Rifampicin-Allantoin_downregulated
WBPaper00055354:Rapamycin-Rifampicin_downregulated
WBPaper00055354:Rifampicin-Allantoin_downregulated
WBPaper00055354:Rifampicin_downregulated
WBPaper00055386:eat-2(ad465)_upregulated
WBPaper00056284:ints-2(RNAi)_downregulated
WBPaper00056326:zip-3(gk3164)_upregulated_P.aeruginosa-infected
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
WBPaper00056471:S.aureus-4h_downregulated_N2
WBPaper00056731:human-amylin_downregulated
WBPaper00056809:smn-1(ok355)_downregulated
WBPaper00056826:hmc_biased
WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
WBPaper00057006:DietaryRestriction_downregulated
WBPaper00058598:sin-3(tm1276)_downregulated
WBPaper00058691:sin-3(tm1276)_downregulated
WBPaper00058711:paraquat_downregulated
WBPaper00058948:PA14_downregulated
WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
WBPaper00059328:mrps-5(RNAi)_upregulated_protein
WBPaper00059604:fluvastatin_upregulated_N2
WBPaper00059664:srbc-48(ac23)_upregulated
WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
WBPaper00059839:S.maltophilia_regulated
WBPaper00059895:wounding_downregulated
WBPaper00059987:Wounding_downregulated
WBPaper00060084:cco-1(RNAi)_downregulated_N2
WBPaper00060100:SiNP_downregulated_mRNA
WBPaper00060358:B.thuringiensis_non-pathogen_regulated_elt-2(RNAi)
WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
WBPaper00060661:sensory-neuron_depleted
WBPaper00060811:L1_vs_adult_downregulated_neural
WBPaper00060871:M.humicola-infection_48h_regulated
WBPaper00060909:atfs-1(cmh15)_downregulated
WBPaper00061203:let-418(n3536)_upregulated
WBPaper00061203:sin-3(tm1276)_upregulated
WBPaper00061203:spr-1(ok2144)_upregulated
WBPaper00061340:Intestine
WBPaper00061341:28C_48h_downregulated
WBPaper00061439:unc-30(ok613)_upregulated
WBPaper00061527:R10H10.3-T21H3.1
WBPaper00061651:Intestine_enriched
WBPaper00061753:csr-1(tor159)_upregulated_25C
WBPaper00061902:camt-1(ok515)_regulated_RMG
WBPaper00062193:skn-1(RNAi)_upregulated
WBPaper00062325:muscle_depleted_coding-RNA
WBPaper00062669:extracellular-vesicle_protein
WBPaper00064071:NHR-49_interacting
WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
WBPaper00064229:B.thuringiensis-Cry5Ba_upregulated
WBPaper00064716:paraquat_downregulated
WBPaper00064933:bcf-1(ylf1)_downregulated_transcript
WBPaper00065086:JU1400_N.ausubeli_regulated
WBPaper00065086:JU1400_N.ferruginous_regulated
WBPaper00065086:N2_N.ausubeli_regulated
WBPaper00065096:Day10_vs_Day1_downregulated
WBPaper00065120:body-muscle-transcriptome
WBPaper00065835:Day11_vs_Day1_downregulated
WBPaper00065835:mtH2S-AP39-D0-treatment_upregulated_Day11
WBPaper00065841:3_0
WBPaper00065841:3_1
WBPaper00065841:3_2
WBPaper00065841:3_4
WBPaper00065841:3_5
WBPaper00065841:18_0
WBPaper00065841:20_2
WBPaper00065841:30_3
WBPaper00065841:137_0
WBPaper00065945:epidermis-rpoa-2(-)_upregulated_protein
WBPaper00065975:P-body_vs_WholeAnimal_depleted
WBPaper00065984:pals-17(syb3980)_downregulated
WBPaper00065993:glp-1(e2141)_upregulated
WBPaper00066110:Doxorubicin_upregulated_diploid
cgc4386_cluster_1_5
cgc4489_group_25
WBPaper00005124:cholesterol_10-9M_regulated
WBPaper00025032:cluster_5
WBPaper00025141:N2_Expressed_Genes
WBPaper00025141:unc-4::GFP_Expressed_Genes
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00026980:intestine_enriched
WBPaper00031060:2-deoxy-D-glucose_upregulated
WBPaper00031532:Larva_Pan_Neuronal_Depleted
WBPaper00031832:slr-2_regulated
WBPaper00032062:age_regulated_genes
WBPaper00035227:heat_shock_regulated
WBPaper00035504:daf-2(e1370)_upregulated
WBPaper00035873:dpy-9_regulated
WBPaper00035873:dpy-10_regulated
WBPaper00036286:Pattern_I
WBPaper00037113:Chlorpyrifos_Diazinon_16C_regulated
WBPaper00037695:LD_3-day
WBPaper00037695:WC_5-day
WBPaper00038060:SUMO-1_downregulated
WBPaper00038231:Cry5B_1.5-fold_downregulated
WBPaper00038231:Cry5B_2-fold_downregulated
WBPaper00038462:aging_downregulated
WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.2
WBPaper00040858:eQTL_age_regulated_aging
WBPaper00040963:Q50_up
WBPaper00040963:TA100_up
WBPaper00040963:TA300_up
WBPaper00041002:HF_3d_2.0mM_Up
WBPaper00041002:HF_11d_0.2mM_Up
WBPaper00041002:HF_11d_2.0mM_Down
WBPaper00041002:HQ_3d_2.0mM_Up
WBPaper00041606:CE_X.nematophila_regulated
WBPaper00041906:I-3690_vs_OP50_3d
WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
WBPaper00044091:Bpseudomallei_repressed_12h
WBPaper00044535:male_downregulated
WBPaper00045673:colistin_upregulated
WBPaper00048989:eat-2(ad465)_rapamycin_upregulated
WBPaper00048989:N2_allantoin_upregulated
WBPaper00057098:SiO2-nanoparticles_downregulated
[cgc5767]:cluster_2
[cgc5767]:expression_class_E
[cgc5767]:expression_class_E_pi(83_min)
[cgc5767]:expression_class_SE
[cgc5767]:expression_class_SE_pi(83_min)
Interaction (21)
Map_infoPositivePositive_cloneR09H10Inferred_automaticallyFrom sequence, transcript, pseudogene data
Interpolated_map_positionIV4.64132
ReferenceWBPaper00032062
WBPaper00038491
WBPaper00055090
WBPaper00065331
MethodGene