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WormBase Tree Display for Gene: WBGene00011003

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Name Class

WBGene00011003SMapS_parentSequenceR04B5
IdentityVersion1
NameSequence_nameR04B5.5
Molecular_nameR04B5.5
R04B5.5.1
CE06215
Other_nameCELE_R04B5.5Accession_evidenceNDBBX284605
Public_nameR04B5.5
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:52WBPerson1971EventImportedInitial conversion from CDS class of WS125
StatusLive
Gene_infoBiotypeSO:0001217
Allele (22)
StrainWBStrain00037671
WBStrain00037708
RNASeq_FPKM (74)
GO_annotation00072473
00072474
00072475
00072476
00118318
Ortholog (42)
Paralog (11)
Structured_descriptionConcise_descriptionR04B5.5 encodes one of two C. elegans sorbitol dehydrogense orthologs; by homology the product of R04B5.5 is predicted to catalyze the reversible oxidation of sorbitol to fructose in the presence of NAD+; in the embryo, an R04B5.5::gfp fusion is expressed in body wall muscle, gut, and tail hypodermis.Paper_evidenceWBPaper00031003
Curator_confirmedWBPerson1843
Date_last_updated17 Nov 2008 00:00:00
Automated_descriptionPredicted to enable L-iditol 2-dehydrogenase activity. Predicted to be involved in sorbitol catabolic process. Expressed in body wall musculature and intestine. Human ortholog(s) of this gene implicated in sorbitol dehydrogenase deficiency with peripheral neuropathy. Is an ortholog of human SORD (sorbitol dehydrogenase).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0081376Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11184)
Molecular_infoCorresponding_CDSR04B5.5
Corresponding_transcriptR04B5.5.1
Other_sequence (43)
Associated_featureWBsf232328
Experimental_infoRNAi_resultWBRNAi00034577Inferred_automaticallyRNAi_primary
WBRNAi00017394Inferred_automaticallyRNAi_primary
WBRNAi00051226Inferred_automaticallyRNAi_primary
WBRNAi00075888Inferred_automaticallyRNAi_primary
Expr_patternExpr4917
Expr1016393
Expr1034823
Expr1154931
Expr2005365
Expr2023586
Drives_constructWBCnstr00012330
WBCnstr00031001
Construct_productWBCnstr00031001
Microarray_results (20)
Expression_cluster (170)
Interaction (41)
Map_infoPositivePositive_cloneR04B5Inferred_automaticallyFrom sequence, transcript, pseudogene data
Interpolated_map_positionV2.27378
ReferenceWBPaper00031003
WBPaper00038491
WBPaper00055090
MethodGene