WormBase Tree Display for Gene: WBGene00010988
expand all nodes | collapse all nodes | view schema
WBGene00010988 | SMap | S_parent | Sequence | R03D7 | |||
---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||
Name | CGC_name | metr-1 | Person_evidence | WBPerson1711 | |||
Sequence_name | R03D7.1 | ||||||
Molecular_name | R03D7.1 | ||||||
R03D7.1.1 | |||||||
CE01609 | |||||||
Other_name | CELE_R03D7.1 | Accession_evidence | NDB | BX284602 | |||
Public_name | metr-1 | ||||||
DB_info | Database (13) | ||||||
Species | Caenorhabditis elegans | ||||||
History | Version_change (2) | ||||||
Status | Live | ||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | metr | ||||||
Allele (55) | |||||||
Strain | WBStrain00001842 | ||||||
WBStrain00002165 | |||||||
WBStrain00031469 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (23) | |||||||
Ortholog (39) | |||||||
Paralog | WBGene00015512 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||
WBGene00020491 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||
Structured_description | Concise_description | metr-1 encodes a protein orthologous to the human gene Methionine synthase (MTR), which is involved in the conversion of homocysteine to form methionine. | Paper_evidence | WBPaper00042203 | |||
Curator_confirmed | WBPerson324 | ||||||
WBPerson1823 | |||||||
WBPerson567 | |||||||
Date_last_updated | 07 May 2013 00:00:00 | ||||||
Automated_description | Predicted to enable methionine synthase activity. Predicted to be involved in homocysteine metabolic process; methionine biosynthetic process; and tetrahydrofolate metabolic process. Predicted to be located in cytosol. Used to study type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in several diseases, including IgA glomerulonephritis; autistic disorder; and hematologic cancer (multiple). Is an ortholog of human MTR (5-methyltetrahydrofolate-homocysteine methyltransferase). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Experimental_model | DOID:9352 | Homo sapiens | Paper_evidence | WBPaper00042203 | ||
Curator_confirmed | WBPerson324 | ||||||
Date_last_updated | 13 Mar 2023 00:00:00 | ||||||
Potential_model (14) | |||||||
Models_disease_asserted | WBDOannot00000175 | ||||||
Molecular_info | Corresponding_CDS | R03D7.1 | |||||
Corresponding_transcript | R03D7.1.1 | ||||||
Other_sequence (51) | |||||||
Associated_feature | WBsf222084 | ||||||
WBsf222085 | |||||||
Experimental_info | RNAi_result | WBRNAi00071221 | Inferred_automatically | RNAi_primary | |||
WBRNAi00034551 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00090587 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00051170 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00106971 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00017346 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Chronogram417 | ||||||
Chronogram1093 | |||||||
Expr6447 | |||||||
Expr6448 | |||||||
Expr1028258 | |||||||
Expr1034818 | |||||||
Expr1154877 | |||||||
Expr2013538 | |||||||
Expr2031772 | |||||||
Drives_construct | WBCnstr00002636 | ||||||
WBCnstr00004383 | |||||||
Regulate_expr_cluster | WBPaper00060951:metr-1(os521)_downregulated | ||||||
WBPaper00060951:metr-1(os521)_upregulated | |||||||
Microarray_results (20) | |||||||
Expression_cluster (213) | |||||||
Interaction (110) | |||||||
Map_info (3) | |||||||
Reference (25) | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |