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WormBase Tree Display for Gene: WBGene00010552

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Name Class

WBGene00010552SMapS_parentSequenceK04C1
IdentityVersion1
NameSequence_nameK04C1.2
Molecular_nameK04C1.2a
K04C1.2a.1
CE06086
K04C1.2b
CE18848
K04C1.2b.1
Other_nameCELE_K04C1.2Accession_evidenceNDBBX284606
Public_nameK04C1.2
DB_infoDatabaseAceViewgeneXO859
WormQTLgeneWBGene00010552
WormFluxgeneWBGene00010552
NDBlocus_tagCELE_K04C1.2
NCBIgene181532
RefSeqproteinNM_077972.7
NM_077971.8
TREEFAMTREEFAM_IDTF351323
TrEMBLUniProtAccQ21205
Q9XVV7
UniProt_GCRPUniProtAccQ9XVV7
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:51WBPerson1971EventImportedInitial conversion from CDS class of WS125
StatusLive
Gene_infoBiotypeSO:0001217
Allele (56)
RNASeq_FPKM (74)
OrthologWBGene00060128Caenorhabditis remaneiFrom_analysisOMA
WBGene00023895Caenorhabditis briggsaeFrom_analysisInparanoid_8
Sp34_X0113310Caenorhabditis inopinataFrom_analysisWormBase-Compara
chrX_pilon.g20544Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00125506Caenorhabditis japonicaFrom_analysisWormBase-Compara
ParalogWBGene00004945Caenorhabditis elegansFrom_analysisTreeFam
WormBase-Compara
Structured_descriptionConcise_descriptionK04C1.2 encodes a protein most closely related to the C. elegans SOP-2 Polycomb group protein; the product of K04C1.2 contains, at its C terminus, a region that has similarity to the SAM (sterile alpha motif) domain, an evolutionarily conserved protein-protein interaction domain of approximately 70 amino acids; although the similarity between SOP-2 and K04C1.2 extends through the SAM domain, replacement of the SOP-2 SAM domain with that of K04C1.2 leads to aberrant localization of the chimeric protein, illustrating that the two SAM domains are not functionally conserved.Paper_evidenceWBPaper00006514
Curator_confirmedWBPerson1843
Date_last_updated20 Aug 2008 00:00:00
Automated_descriptionEnriched in several structures, including ABalaaaarl; ABalaaaarr; ABplpaaaap; PVR; and mechanosensory neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; sir-2.1; and pgl-1 based on microarray and RNA-seq studies. Is affected by four chemicals including Zidovudine; paraquat; and Chlorpyrifos based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Sterile alpha motif/pointed domain superfamily.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSK04C1.2a
K04C1.2b
Corresponding_transcriptK04C1.2a.1
K04C1.2b.1
Associated_featureWBsf648724
WBsf1007859
WBsf1024372
WBsf236659
WBsf236660
Transcription_factorWBTranscriptionFactor000331
Experimental_infoRNAi_resultWBRNAi00049883Inferred_automaticallyRNAi_primary
WBRNAi00016581Inferred_automaticallyRNAi_primary
Expr_patternExpr1027113
Expr1034604
Expr1153588
Expr2004756
Expr2022980
Drives_constructWBCnstr00031332
Construct_productWBCnstr00031332
Microarray_results (24)
Expression_clusterWBPaper00032976:non_compensated_genes
WBPaper00033065:cyc-1(RNAi)_downregulated
WBPaper00036375:enriched_in_PVD_OLL
WBPaper00037950:bodywall-muscle_L2-larva_expressed
WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
WBPaper00037950:excretory-cell_L2-larva_expressed
WBPaper00037950:hypodermis_L3-L4-larva_expressed
WBPaper00037950:intestine_L2-larva_expressed
WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
WBPaper00041222:unc-120(st364)_downregulated
WBPaper00044736:flat_dev_expression
WBPaper00045521:Oogenic
WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
WBPaper00048988:neuron_expressed
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
WBPaper00050726:OsmoticStress_regulated_Food
WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
WBPaper00050990:GABAergic-neuron_expressed
WBPaper00050990:intestine_expressed
WBPaper00051265:F4_hrde-1(tm1200)_upregulated
WBPaper00053184:sma-4(rax3)_downregulated
WBPaper00053302:zidovudine_72h_regulated
WBPaper00053321:embryo-to-L1_upregulated_nos-1(gv5)nos-2(RNAi)_SMARTseq
WBPaper00053321:lin-15B(RNAi)_downregulated_starved-L1_Truseq
WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_fed-L1_Truseq
WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_starved-L1_Truseq
WBPaper00053599:female_vs_male_upregulated
WBPaper00053599:oocyte_vs_mitosis_downregulated
WBPaper00053810:nuo-6(qm200)_upregulated
WBPaper00055334:DLC-1_interacting
WBPaper00055386:daf-2(e1370)_downregulated
WBPaper00055804:FBF-1-FBF-2-associated_oogenic-enriched
WBPaper00055971:nhl-2(ok818)_25C_upregulated
WBPaper00056161:hermaphrodite_enriched_siRNA
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
WBPaper00056826:SGP_biased
WBPaper00057288:Cold_downregulated_transcript
WBPaper00057288:iff-1(RNAi)_downregulated_transcript
WBPaper00058691:cfp-1(tm6369)_downregulated
WBPaper00058691:set-2(bn129)_downregulated
WBPaper00058725:sftb-1(cer6)_downregulated
WBPaper00059356:BAZ-2_SET-6_interacting
WBPaper00059471:EGL-43_interacting
WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
WBPaper00060399:pqm-1(ok485)_downregulated_CoCl2_6hr
WBPaper00060811:L1_vs_adult_upregulated_neural
WBPaper00061007:S.aquatilis_downregulated
WBPaper00061340:Parent_of_exc_duct_pore_DB_1_3
WBPaper00061340:PLM
WBPaper00061340:PVR
WBPaper00061340:RME_LR_parent
WBPaper00061439:unc-30(ok613)_downregulated
WBPaper00061466:nath-10(icb102)_downregulated
WBPaper00061527:chd-7_16664-jmjd-3.1
WBPaper00062354:H.zoospora_6h_regulated
WBPaper00064315:mes-3(bn199)_upregulated_EGCs
WBPaper00064315:mes-3(bn199)_upregulated_PGCs
WBPaper00064315:mes-4(bn73)_upregulated_EGCs
WBPaper00064315:mes-4(bn73)_upregulated_PGCs
WBPaper00064315:mrg-1(qa6200)_upregulated_PGCs
WBPaper00064716:paraquat_upregulated
WBPaper00065096:25C_vs_20C_upregulated
WBPaper00065096:Day10_vs_Day1_upregulated
WBPaper00025032:cluster_116
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00027111:eri-1(mg366)_upregulated
WBPaper00035873:dpy-9_regulated
WBPaper00035905:FBF-1_Associated
WBPaper00037113:Chlorpyrifos_Diazinon_16C_regulated
WBPaper00037611:RNP-8-associated
WBPaper00040210:Chlorpyrifos_Diazinon_24C_regulated
WBPaper00040858:eQTL_age_regulated_aging
WBPaper00040858:eQTL_regulated_old
WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
WBPaper00045263:0.1mM-paraquat_upregulated
WBPaper00045263:isp-1(qm150)_upregulated
WBPaper00045263:nuo-6(qm200)_upregulated
WBPaper00045263:ProLongevity-mtROS_upregulated
[cgc5767]:expression_class_M
[cgc5767]:expression_class_SM
InteractionWBInteraction000178623
WBInteraction000185065
WBInteraction000539396
Map_infoPositivePositive_cloneK04C1Inferred_automaticallyFrom sequence, transcript, pseudogene data
Interpolated_map_positionX16.6702
ReferenceWBPaper00006514
MethodGene