WormBase Tree Display for Gene: WBGene00008512

WBGene00008512 SMap: S_parent: Sequence: F01G10
  Identity: Version: 1
    Name: Sequence_name: F01G10.10
      Molecular_name: F01G10.10
        F01G10.10.1
        CE40351
      Other_name: CELE_F01G10.10 Accession_evidence: NDB BX284604
      Public_name: F01G10.10
    DB_info: Database: AceView gene 4L13
        WormQTL gene WBGene00008512
        WormFlux gene WBGene00008512
        NDB locus_tag CELE_F01G10.10
        Panther gene CAEEL|WormBase=WBGene00008512|UniProtKB=O17768
          family PTHR10504
        NCBI gene 177907
        RefSeq protein NM_069478.6
        TREEFAM TREEFAM_ID TF317549
        TrEMBL UniProtAcc O17768
        UniProt_GCRP UniProtAcc O17768
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:49 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
    Status: Live
  Gene_info: Biotype: SO:0001217
    Allele (45)
    RNASeq_FPKM (74)
    GO_annotation: 00030663
      00116411
    Ortholog (41)
    Paralog: WBGene00016951 Caenorhabditis elegans From_analysis: TreeFam
            WormBase-Compara
      WBGene00008652 Caenorhabditis elegans From_analysis: TreeFam
            WormBase-Compara
      WBGene00018403 Caenorhabditis elegans From_analysis: TreeFam
            WormBase-Compara
      WBGene00015544 Caenorhabditis elegans From_analysis: TreeFam
            WormBase-Compara
      WBGene00003812 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00007325 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00015545 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00020563 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00022627 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Automated_description: Predicted to enable lipid binding activity. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in Crohn's disease and severe acute respiratory syndrome. Is an ortholog of human LBP (lipopolysaccharide binding protein). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:8778 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1095)
      DOID:2945 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1095)
  Molecular_info: Corresponding_CDS: F01G10.10
    Corresponding_CDS_history: F01G10.10:wp162
    Corresponding_transcript: F01G10.10.1
    Other_sequence (19)
    Associated_feature: WBsf646295
  Experimental_info: RNAi_result: WBRNAi00030547 Inferred_automatically: RNAi_primary
      WBRNAi00043763 Inferred_automatically: RNAi_primary
      WBRNAi00012743 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1014887
      Expr1033704
      Expr1147741
      Expr2002198
      Expr2020419
    Drives_construct: WBCnstr00032908
    Construct_product: WBCnstr00032908
    Microarray_results (19)
    Expression_cluster: WBPaper00037950:hypodermis_CoreEnriched
      WBPaper00037950:hypodermis_embryo_enriched
      WBPaper00037950:hypodermis_embryo_SelectivelyEnriched
      WBPaper00037950:hypodermis_larva_enriched
      WBPaper00037950:hypodermis_larva_SelectivelyEnriched
      WBPaper00038438:E.faecalis_24hr_upregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_upregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
      WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
      WBPaper00040221:DAF-12_target_ALF4
      WBPaper00041954:ethanol_upregulated
      WBPaper00042477:prp-8(RNAi)_downregulated_RNAseq
      WBPaper00043945:MeHg_upregulated
      WBPaper00044260:1-methylnicotinamide_upregulated
      WBPaper00044736:oscillating_dev_expression
      WBPaper00044760:somatic_specific
      WBPaper00045521:Gender_Neutral
      WBPaper00046012:tdp-1(ok803)_upregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_upregulated
      WBPaper00049920:Glucose-Diet_upregulated_hyl-2(tm2031)
      WBPaper00050344:AFD-neuron_enriched
      WBPaper00050370:dpy-21(e428)_L3_downregulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050801:DAF-12_dauer_regulome
      WBPaper00050801:DAF-16_dauer_regulome
      WBPaper00050801:DPY-21_dauer_regulome
      WBPaper00050990:hypodermis_enriched
      WBPaper00050990:hypodermis_expressed
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053308:SMG-2_associated_NMD(-)_unaltered_ClassII
      WBPaper00053388:dauer_regulated_Cluster5
      WBPaper00053402:cco-1(RNAi)_downregulated
      WBPaper00053810:nuo-6(qm200)_downregulated
      WBPaper00055013:hmg-3(bar24)_downregulated
      WBPaper00055013:hmg-4(RNAi)_downregulated
      WBPaper00055013:spt-16(RNAi)_downregulated
      WBPaper00055049:S.gordonii_upregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rapamycin-Psora_downregulated
      WBPaper00055354:Rapamycin-Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rifampicin-Psora_downregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055386:daf-2(e1370)_upregulated
      WBPaper00055626:pry-1(mu38)_downregulated
      WBPaper00055941:atfs-1(et15)_upregulated
      WBPaper00055941:nuo-6(qm200)_downregulated
      WBPaper00055971:nhl-2(ok818)_25C_downregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056169:rrf-3(pk1426)_downregulated_L4
      WBPaper00056330:glycine_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00057041:spc-1(cas971)_upregulated
      WBPaper00057041:unc-70(cas983)_upregulated
      WBPaper00057068:ints-4(RNAi)_downregulated_Cadmium
      WBPaper00057154:HeatShock_downregulated_miRNA-target
      WBPaper00057154:HeatShock_upregulated_mRNA
      WBPaper00058598:mex-1(or286)_upregulated
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058598:spn-4(tm291)_upregulated
      WBPaper00058678:DAF-12_downregulated_PVD
      WBPaper00058948:npr-8(ok1439)_downregulated_PA14
      WBPaper00058969:RIS_depleted
      WBPaper00059117:B.subtilis_upregulated
      WBPaper00059231:alh-6(lax105)_L4_upregulated
      WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
      WBPaper00059421:daf-1(m40);daf-3(mgDf90)_downregulated
      WBPaper00059421:daf-3(mgDf90)_downregulated
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059728:5ug_cholesterol_upregulated
      WBPaper00059728:20ug_cholesterol_upregulated
      WBPaper00059739:hira-1(gk835598)_downregulated_L1
      WBPaper00060014:set-2(tm1630)_downregulated
      WBPaper00060273:isp-1(qm150)_upregulated
      WBPaper00060399:pqm-1(ok485)_downregulated_CoCl2_6hr
      WBPaper00060445:nfki-1(cer1)_downregulated_L4
      WBPaper00060683:hlh-11(ko1)_upregulated
      WBPaper00060764:swsn-1(os22ts)_upregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00061007:HB101_upregulated
      WBPaper00061007:S.aquatilis_upregulated
      WBPaper00061007:X.citri_upregulated
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061340:AMso
      WBPaper00061340:ant_arc_V
      WBPaper00061340:Hypodermis
      WBPaper00061340:Tail_hypodermis
      WBPaper00061424:Diet_MYb120_upregulated
      WBPaper00061439:unc-30(ok613)_upregulated_P.aeruginosa-infection
      WBPaper00061527:C38C6.3-acdh-6
      WBPaper00061613:human-alpha-Synuclein(A53T)_upregulated
      WBPaper00061753:csr-1(tor159)_upregulated_25C
      WBPaper00062156:jmjd-1.2(zr1010)_upregulated
      WBPaper00062156:jmjd-5(zr1234)_upregulated
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062193:hsf-1(RNAi)_downregulated
      WBPaper00062193:skn-1(RNAi)_downregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062345:bortezomib_4h_upregulated_zip-1(jy13)
      WBPaper00062440:crh-1(n3315)_downregulated
      WBPaper00062446:nhr-8(hd117)_upregulated
      WBPaper00062534:fat-P-80_downregulated
      WBPaper00062585:hlh-26(ok1453)_upregulated_E.faecium
      WBPaper00062672:let-418(n3536)dcp-66(RNAi)_upregulated
      WBPaper00064005:starvation_downregulated_N2_mRNA
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064229:B.thuringiensis-Cry5Ba_upregulated
      WBPaper00064494:postdauer_downregulated_AWA
      WBPaper00064502:nhr-23(kry61);spe-44(fx110)_upregulated
      WBPaper00064502:spe-44(fx110)_upregulated
      WBPaper00064632:daf-2(e1370)_upregulated_intestine
      WBPaper00064721:fasn-1(g14)_downregulated_starved
      WBPaper00064728:cpl-1(W32AY35A)_upregulated
      WBPaper00064769:him-17(me24)_upregulated
      WBPaper00065074:glna(-)_downregulated
      WBPaper00065096:25C_vs_20C_downregulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065734:unc-25(e156)_downregulated
      WBPaper00065746:eat-2(ad1113)_downregulated
      WBPaper00065841:82_0
      WBPaper00065984:pals-17(syb3980)_downregulated
      WBPaper00066110:tetraploid_vs_diploid_upregulated
      WBPaper00066232:hsf-1(RNAi)_upregulated_WT
      cgc4489_group_5
      WBPaper00005124:estrogen_10-5M_regulated
      WBPaper00026952:class_E
      WBPaper00032948:FedUp
      WBPaper00034739:N2lessDR1350
      WBPaper00035588:alg-1(-)_upregulated
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00036130:mir-243_up_regulated
      WBPaper00036286:Pattern_G
      WBPaper00038172:crh-1null_down_regulated
      WBPaper00038304:octr-1_regulated
      WBPaper00040210:Chlorpyrifos_Diazinon_24C_regulated
      WBPaper00040210:Diazinon_24C_regulated
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00040858:eQTL_age_regulated_aging
      WBPaper00040858:eQTL_regulated_aging
      WBPaper00041174:environmental
      WBPaper00041174:environmental_prime
      WBPaper00041207:CE_dauer_down
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00045673:colistin_upregulated
      WBPaper00046083:oga-1(ok1207)_OP50_downregulated
      WBPaper00046083:ogt-1(ok1474)_OP50_downregulated
      WBPaper00046083:pmk-1(km25)_OP50_downregulated
      WBPaper00047070:N2_starvation_downregulated
      WBPaper00047070:N2_UV_downregulated
      WBPaper00047070:xpa-1_UV_downregulated
      WBPaper00048989:N2_rapamycin_upregulated
      WBPaper00055899:nitroguanidine_regulated
      WBPaper00056330:mrps-5(RNAi)_upregulated
      [cgc6390]:Cluster_B
    Interaction (228)
  Map_info: Positive: Positive_clone: F01G10 Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: IV 4.56406
  Reference: WBPaper00038491
    WBPaper00055090
  Method: Gene