WormBase Tree Display for Gene: WBGene00008352

WBGene00008352 SMap: S_parent: Sequence: cTel54X
  Identity: Version: 2
    Name: CGC_name: fbxa-6 Person_evidence: WBPerson655
      Sequence_name: cTel54X.1
      Molecular_name: cTel54X.1
        cTel54X.1.1
        CE20619
      Other_name: CELE_CTEL54X.1 Accession_evidence: NDB BX284603
      Public_name: fbxa-6
    DB_info: Database: AceView gene 3A620
        WormQTL gene WBGene00008352
        WormFlux gene WBGene00008352
        NDB locus_tag CELE_CTEL54X.1
        Panther gene CAEEL|WormBase=WBGene00008352|UniProtKB=A4F303
          family PTHR23015
        NCBI gene 183881
        RefSeq protein NM_064723.2
        TREEFAM TREEFAM_ID TF322006
        TrEMBL UniProtAcc A4F303
        UniProt_GCRP UniProtAcc A4F303
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:49 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 12 Dec 2005 15:18:56 WBPerson2970 Name_change: CGC_name: fbxa-6
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: fbxa
    Allele (76)
    RNASeq_FPKM (74)
    Ortholog (46)
    Paralog (225)
    Structured_description: Concise_description: This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction. Paper_evidence: WBPaper00012854
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Enriched in dopaminergic neurons; intestine; mechanosensory neurons; and rectal epithelium based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by sixteen chemicals including levamisole; stavudine; and Rifampin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; FTH domain; and F-box A protein FB224. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: cTel54X.1
    Corresponding_transcript: cTel54X.1.1
    Associated_feature: WBsf226070
  Experimental_info: RNAi_result: WBRNAi00068269 Inferred_automatically: RNAi_primary
      WBRNAi00043312 Inferred_automatically: RNAi_primary
      WBRNAi00012484 Inferred_automatically: RNAi_primary
      WBRNAi00068270 Inferred_automatically: RNAi_primary
      WBRNAi00030296 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1015384
      Expr1163307
      Expr2011570
      Expr2029808
    Microarray_results (17)
    Expression_cluster: WBPaper00033065:cyc-1(RNAi)_downregulated
      WBPaper00037950:A-class-motor-neurons_L1-larva_expressed
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:AVE-neuron_L1-larva_expressed
      WBPaper00037950:bodywall-muscle_L1-larva_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:dopaminergic-neurons_larva_enriched
      WBPaper00037950:dopaminergic-neurons_larva_SelectivelyEnriched
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:intestine_CoreEnriched
      WBPaper00037950:intestine_embryo_enriched
      WBPaper00037950:intestine_embryo_SelectivelyEnriched
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:intestine_larva_enriched
      WBPaper00037950:intestine_larva_SelectivelyEnriched
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_larva_enriched
      WBPaper00037950:PVD-OLL-neurons_larva_SelectivelyEnriched
      WBPaper00038168:lin-15B(n744)_upregulated
      WBPaper00038168:lin-35_upregulated
      WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
      WBPaper00040560:hpl-2_embryo_upregulated
      WBPaper00042561:smgl-1(RNAi)_downregulated
      WBPaper00044030:nhr-8(hd117)_downregulated
      WBPaper00044037:eat-2_upregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
      WBPaper00045017:blmp-1(tm548)_downregulated
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045571:germline-ablation_upregulated
      WBPaper00046497:B.thuringiensis_0.1mix_upregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_upregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_upregulated_12h
      WBPaper00046509:htz-1(ok3099)_downregulated
      WBPaper00047131:daf-2(e1370)_upregulated_N2-background
      WBPaper00048971:daf-16(mgDf50)_downregulated_L1
      WBPaper00049177:rpn-10(ok1865)_upregulated
      WBPaper00049334:CE_intestine_enriched
      WBPaper00049732:blmp-1(tm548)_vs_N2_downregulated
      WBPaper00049736:daf-2(e1370)_upregulated_15deg-then-25deg(12hr)
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00051039:intestine_enriched
      WBPaper00051257:Levamisole_upregulated
      WBPaper00051558:aging_regulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053388:dauer_regulated_Cluster2
      WBPaper00053606:N2_vs_elt-2(ca15);elt-7(tm840)_downregulated
      WBPaper00053606:N2_vs_elt-2(ca15)_downregulated
      WBPaper00053664:ins-11(tm1053)_downregulated
      WBPaper00053810:daf-2(e1370)_upregulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00053909:N2_vs_CB4856_upregulated
      WBPaper00055354:Rapamycin-Rifampicin_upregulated
      WBPaper00055354:Rifampicin-Allantoin_upregulated
      WBPaper00055354:Rifampicin-Psora_upregulated
      WBPaper00055386:daf-2(e1370)_upregulated
      WBPaper00055482:Tunicamycin_upregulated
      WBPaper00055827:daf-2(e1370)_upregulated
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056284:ints-5(RNAi)_upregulated
      WBPaper00056284:ints-6(t1903)_upregulated
      WBPaper00056550:ceh-60(ok1485)_upregulated_AdultDay1
      WBPaper00057041:spc-1(cas971)_downregulated
      WBPaper00057041:unc-70(cas983)_downregulated
      WBPaper00057068:ints-4(RNAi)_downregulated
      WBPaper00058598:mex-1(or286)_upregulated
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:spn-4(tm291)_upregulated
      WBPaper00058711:paraquat_downregulated
      WBPaper00058711:wdr-5(ok1417)_downregulated
      WBPaper00058948:PA14_downregulated
      WBPaper00059117:B.subtilis_upregulated
      WBPaper00059191:hsp-16.2p-LIN-29_downregulated
      WBPaper00059253:stearic-acid_upregulated
      WBPaper00059356:BAZ-2_SET-6_interacting
      WBPaper00059421:daf-1(m40)_upregulated
      WBPaper00059421:daf-3(mgDf90)_downregulated
      WBPaper00059440:LAG-1_interacting_germline
      WBPaper00059440:LAG-1_interacting_WholeAnimal
      WBPaper00059839:S.maltophilia_regulated
      WBPaper00060100:SiNP_downregulated_mRNA
      WBPaper00060273:isp-1(qm150)_upregulated
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060399:pqm-1(ok485)_upregulated_CoCl2_6hr
      WBPaper00060909:atfs-1(cmh15)_downregulated
      WBPaper00060911:prx-5(RNAi)_upregulated_mRNA
      WBPaper00061007:S.aquatilis_upregulated
      WBPaper00061274:hypergravity_10xg_downregulated
      WBPaper00061274:hypergravity_15xg_downregulated
      WBPaper00061319:pnp-1(jy90)_upregulated
      WBPaper00061319:pnp-1(jy121)_upregulated
      WBPaper00061340:F_U
      WBPaper00061341:28C_48h_downregulated
      WBPaper00061527:syd-1_2945-unc-41_2170
      WBPaper00061530:nhr-49(e2144)_downregulated
      WBPaper00061699:daf-18(ok480)_downregulated
      WBPaper00061753:csr-1(tor159)_upregulated_25C
      WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
      WBPaper00062056:lin-15B(we23)_downregulated
      WBPaper00062056:lin-36(we31)_downregulated
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062193:skn-1(RNAi)_downregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062345:bortezomib_4h_upregulated_N2
      WBPaper00062440:crh-1(n3315)_downregulated
      WBPaper00062440:crh-1(syb385)_downregulated
      WBPaper00064005:starvation_upregulated_aptf-1(gk794)_mRNA
      WBPaper00064005:starvation_upregulated_N2_mRNA
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064107:lin-35(n745)_upregulated
      WBPaper00064229:B.thuringiensis-Cry5Ba_upregulated
      WBPaper00064532:pals-22(jy3)_upregulated
      WBPaper00064632:daf-2(e1370)_upregulated_intestine
      WBPaper00064716:paraquat_downregulated
      WBPaper00064871:hypoxia_downregulated_F1
      WBPaper00065086:JU1400_N.ferruginous_regulated
      WBPaper00065086:JU1400_N.ironsii_regulated
      WBPaper00065086:JU1400_N.parisii_regulated
      WBPaper00065086:N2_N.ferruginous_regulated
      WBPaper00065086:N2_N.ironsii_regulated
      WBPaper00065096:25C_vs_20C_downregulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065746:tmc-1(rg1003)_downregulated
      WBPaper00065749:endu-2(tm4977)_upregulated
      WBPaper00065841:19_0
      WBPaper00065841:69_0
      WBPaper00065841:119_0
      WBPaper00065877:rege-1(imm070)_downregulated_OP50
      WBPaper00065877:rege-1(imm070)_downregulated_PA14
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066110:Cisplatin_upregulated_diploid
      WBPaper00066110:Doxorubicin_upregulated_diploid
      WBPaper00066110:tetraploid_vs_diploid_upregulated
      WBPaper00066232:ash-2(RNAi)_downregulated_WT
      WBPaper00066232:hsf-1(RNAi)_upregulated_ash-2
      WBPaper00066232:hsf-1(RNAi)_upregulated_WT
      cgc4386_cluster_4_4
      WBPaper00032948:StarveUp3
      WBPaper00034757:up_by_oxidative_stress
      WBPaper00035227:heat_shock_regulated
      WBPaper00035479:daf-16(RNAi)_downregulated
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00037695:WC_5-day
      WBPaper00038231:Cry5B_1.5-fold_downregulated
      WBPaper00038231:Cry5B_2-fold_downregulated
      WBPaper00039866:ClassComp_daf-19_downregulated
      WBPaper00039866:SAM_daf-19_downregulated
      WBPaper00040184:hcf-1up_sir-2.1nc_daf-2up
      WBPaper00040858:eQTL_age_regulated_developing
      WBPaper00040858:eQTL_regulated_developing
      WBPaper00040858:eQTL_regulated_juvenile
      WBPaper00040858:eQTL_regulated_old
      WBPaper00040963:Q100_up
      WBPaper00040963:Q200_up
      WBPaper00041002:HF_3d_0.2mM_Up
      WBPaper00044091:Bpseudomallei_repressed_12h
      WBPaper00045263:nuo-6(qm200)_upregulated
      WBPaper00047021:MWCNT_downregulated
      WBPaper00053236:daf-16(mgDF50)_regulated_Starved
      WBPaper00053236:Starvation_regulated_N2
      WBPaper00053550:daf-19(m86)_downregulated_3-fold-embryo
      WBPaper00057098:SiO2-nanoparticles_upregulated
  Map_info: Map: III Position: -27.2913
    Positive: Positive_clone: cTel54X Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00012854
    WBPaper00041771
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene