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WormBase Tree Display for Gene: WBGene00007848

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Name Class

WBGene00007848SMapS_parentSequenceC31E10
IdentityVersion2
NameCGC_namecytb-5.1Person_evidenceWBPerson681
Sequence_nameC31E10.7
Molecular_nameC31E10.7
C31E10.7.1
CE37487
Other_namecytochrome b5Paper_evidenceWBPaper00040883
CELE_C31E10.7Accession_evidenceNDBBX284606
Public_namecytb-5.1
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:48WBPerson1971EventImportedInitial conversion from CDS class of WS125
230 Sep 2011 16:40:15WBPerson2970Name_changeCGC_namecytb-5.1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcytb
Allele (24)
RNASeq_FPKM (74)
GO_annotation00085658
00085659
00085660
00085661
00085662
00085663
00085664
00085665
Ortholog (48)
ParalogWBGene00010235Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00014300Caenorhabditis elegansFrom_analysisPanther
WBGene00020931Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptioncytb-5.1 encodes a protein orthologous to cytochrome b5; a CYTB-5.1 reporter fusion protein, when expressed in the distal tip cell, exhibits perinuclear localization, consistent with localization to the endoplasmic reticulum.Paper_evidenceWBPaper00040883
Curator_confirmedWBPerson1843
WBPerson1823
WBPerson567
Date_last_updated16 Mar 2012 00:00:00
Automated_descriptionPredicted to enable heme binding activity. Located in perinuclear region of cytoplasm. Used to study hematopoietic system disease. Human ortholog(s) of this gene implicated in methemoglobinemia; methemoglobinemia and ambiguous genitalia; and stomatitis. Is an ortholog of human CYB5A (cytochrome b5 type A) and CYB5B (cytochrome b5 type B).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoExperimental_modelDOID:74Homo sapiensPaper_evidenceWBPaper00053474
Curator_confirmedWBPerson324
Date_last_updated09 May 2023 00:00:00
Potential_modelDOID:0112316Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2570)
DOID:10783Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2570)
DOID:9637Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2570)
Models_disease_in_annotationWBDOannot00000049
Molecular_infoCorresponding_CDSC31E10.7
Corresponding_CDS_historyC31E10.7:wp132
Corresponding_transcriptC31E10.7.1
Other_sequence (80)
Associated_featureWBsf648705
WBsf655229
WBsf663528
WBsf1007797
WBsf1024340
WBsf236630
WBsf236631
WBsf236632
Experimental_infoRNAi_resultWBRNAi00033345Inferred_automaticallyRNAi_primary
WBRNAi00024689Inferred_automaticallyRNAi_primary
WBRNAi00071638Inferred_automaticallyRNAi_primary
WBRNAi00111894Inferred_automaticallyRNAi_primary
WBRNAi00008470Inferred_automaticallyRNAi_primary
WBRNAi00105933Inferred_automaticallyRNAi_primary
WBRNAi00071637Inferred_automaticallyRNAi_primary
WBRNAi00041615Inferred_automaticallyRNAi_primary
WBRNAi00088736Inferred_automaticallyRNAi_primary
WBRNAi00088629Inferred_automaticallyRNAi_primary
Expr_patternExpr13447
Expr1024592
Expr1033402
Expr1145640
Expr2010751
Expr2028988
Drives_constructWBCnstr00033436
Construct_productWBCnstr00000237
WBCnstr00033436
WBCnstr00040361
Microarray_results (20)
Expression_cluster (180)
Interaction (55)
Map_infoMapXPosition15.9609
PositivePositive_cloneC31E10Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00034497
WBPaper00034498
WBPaper00038491
WBPaper00040883
WBPaper00053474
WBPaper00055090
WBPaper00060223
WBPaper00061328
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene