WormBase Tree Display for Gene: WBGene00007108

WBGene00007108 SMap: S_parent: Sequence: B0035
  Identity: Version: 2
    Name: CGC_name: gspd-1 Person_evidence: WBPerson1847
      Sequence_name: B0035.5
      Molecular_name: B0035.5
        B0035.5.1
        CE05163
      Other_name: CELE_B0035.5 Accession_evidence: NDB BX284604
      Public_name: gspd-1
    DB_info: Database (13)
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:47 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 08 Jan 2009 14:49:49 WBPerson2970 Name_change: CGC_name: gspd-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: gspd
    Allele (37)
    Strain: WBStrain00001297
      WBStrain00001298
      WBStrain00051071
      WBStrain00051070
    RNASeq_FPKM (74)
    GO_annotation (20)
    Contained_in_operon: CEOP4436
    Ortholog (40)
    Structured_description: Concise_description: gspd-1 encodes a protein orthologous to human GLUCOSE-6-PHOSPHATE DEHYDROGENASE (G6PD; OMIM:305900), which when mutated leads to disease. Curator_confirmed: WBPerson1843
            WBPerson1823
            WBPerson567
          Date_last_updated: 14 Dec 2009 00:00:00
      Automated_description: Predicted to enable glucose-6-phosphate dehydrogenase activity. Predicted to be involved in glucose metabolic process and pentose-phosphate shunt, oxidative branch. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in several diseases, including Plasmodium falciparum malaria; diabetes mellitus (multiple); and favism. Is an ortholog of human G6PD (glucose-6-phosphate dehydrogenase). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model (11)
  Molecular_info: Corresponding_CDS: B0035.5
    Corresponding_transcript: B0035.5.1
    Other_sequence (125)
    Associated_feature: WBsf997808
      WBsf229141
  Experimental_info: RNAi_result (32)
    Expr_pattern: Chronogram959
      Expr5017
      Expr1017929
      Expr1033057
      Expr1142886
      Expr2012290
      Expr2030526
    Drives_construct: WBCnstr00002190
      WBCnstr00002191
      WBCnstr00033992
    Construct_product: WBCnstr00033992
    Microarray_results (19)
    Expression_cluster: WBPaper00029359_1166
      WBPaper00029359_1197
      WBPaper00029359_1291
      WBPaper00029359_1320
      WBPaper00029359_1326
      WBPaper00029359_1345
      WBPaper00029359_1439
      WBPaper00029359_1458
      WBPaper00029359_1546
      WBPaper00029359_1549
      WBPaper00029359_1557
      WBPaper00029359_1599
      WBPaper00029359_1618
      WBPaper00032031:DConiospora_upregulated_cDNA_24h
      WBPaper00032528:L3_enriched
      WBPaper00035269:cde-1_regulated
      WBPaper00037086:biotin_regulated
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038289:oocyte_protein
      WBPaper00038438:P.lumniescens_24hr_upregulated_RNAseq
      WBPaper00040221:DAF-12_target_ALF4
      WBPaper00042215:wdr-23(tm1817)_upregulated
      WBPaper00044128:daf-2(e1370)_upregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044743:wdr-23_neuron_upregulated
      WBPaper00045520:V.alginolyticus_upregulated
      WBPaper00045521:Gender_Neutral
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00046509:htz-1(ok3099)_downregulated
      WBPaper00046509:lin-35(n745)_downregulated
      WBPaper00048910:mRNA-interacting_protein
      WBPaper00048988:neuron_expressed
      WBPaper00049498:npr-1(ur89)_regulated_3
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049942:hsf-1(RNAi)_downregulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050698:DEP-1_interacting
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00051245:body-wall-muscle_cytoplasm_expressed
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:epidermis_nucleus_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051245:intestine_nucleus_expressed
      WBPaper00052884:emb-4(hc60)_downregulated
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053321:PGCs_enriched_NuGen
      WBPaper00053388:dauer_regulated_Cluster1
      WBPaper00053615:SMO-1_target
      WBPaper00055482:Tunicamycin_downregulated
      WBPaper00055626:pry-1(mu38)_downregulated
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_downregulated_N2
      WBPaper00056161:male_enriched_siRNA
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00057140:meg-3(tm4259)_meg-4(ax2026)_upregulated
      WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
      WBPaper00059605:MUT-16_interacting
      WBPaper00060683:hlh-11(ko1)_downregulated
      WBPaper00060909:atfs-1(cmh15)_downregulated
      WBPaper00061341:28C_24h_downregulated
      WBPaper00061341:28C_48h_downregulated
      WBPaper00061527:D1007.4-F33G12.2
      WBPaper00062193:hsf-1(RNAi)_downregulated
      WBPaper00062193:skn-1(RNAi)_downregulated
      WBPaper00062554:MAGU-2_interacting
      WBPaper00062590:Aging_downregulated_hypodermis
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064071:NHR-49_interacting
      WBPaper00064163:ZNFX-1_interacting_embryo
      WBPaper00064163:ZNFX-1_interacting_young-adult
      WBPaper00064716:paraquat_upregulated
      WBPaper00065086:JU1400_N.ausubeli_regulated
      WBPaper00065086:JU1400_N.ferruginous_regulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065373:sek-1(km4)_downregulated_cisplatin
      WBPaper00065841:9_0
      WBPaper00065841:9_1
      WBPaper00065841:9_2
      WBPaper00065841:27_0
      WBPaper00065841:69_0
      WBPaper00066062:xrep-4(lax137)_upregulated
      cgc4489_group_16
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00031003:0hr_muscle_depleted
      WBPaper00031003:total_muscle_depleted
      WBPaper00035424:ASER_down
      WBPaper00036123:Atrazine_regulated
      WBPaper00036123:Cadmium_regulated
      WBPaper00036286:Pattern_G
      WBPaper00038231:Cry5B_1.5-fold_downregulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00053236:Starvation_regulated_GR1307
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_SM
      [cgc6390]:herm_sex-enriched
    Interaction (65)
  Map_info: Map: IV Position: 4.95647 Error: 0.001222
    Positive: Positive_clone: B0035 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (13)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene