WormBase Tree Display for Gene: WBGene00006890
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| WBGene00006890 | Evidence | CGC_data_submission | |||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | K07E3 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | vem-1 | Person_evidence | WBPerson1835 | |||||
| Sequence_name | K07E3.8 | ||||||||
| Molecular_name | K07E3.8 | ||||||||
| K07E3.8.1 | |||||||||
| CE34578 | |||||||||
| Other_name | CELE_K07E3.8 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | vem-1 | ||||||||
| DB_info | Database | AceView | gene | XI706 | |||||
| WormQTL | gene | WBGene00006890 | |||||||
| WormFlux | gene | WBGene00006890 | |||||||
| NDB | locus_tag | CELE_K07E3.8 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00006890|UniProtKB=Q7YZW5 | |||||||
| family | PTHR10281 | ||||||||
| NCBI | gene | 181066 | |||||||
| RefSeq | protein | NM_001029599.11 | |||||||
| SwissProt | UniProtAcc | Q7YZW5 | |||||||
| UniProt_GCRP | UniProtAcc | Q7YZW5 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:43 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | vem | ||||||||
| Allele (34) | |||||||||
| Strain | WBStrain00035774 | ||||||||
| WBStrain00035993 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00082942 | ||||||||
| 00082943 | |||||||||
| 00082944 | |||||||||
| 00082945 | |||||||||
| 00082946 | |||||||||
| 00082947 | |||||||||
| 00082948 | |||||||||
| 00082949 | |||||||||
| 00082950 | |||||||||
| 00082951 | |||||||||
| Ortholog (41) | |||||||||
| Paralog | WBGene00006478 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00012559 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | vem-1 encodes a transmembrane protein that contains a cytochrome b5-like heme/steroid-binding domain and is orthologous to mammalian VEMA, a membrane-associated progesterone receptor component; in C. elegans, vem-1 is required for proper axonal guidance of ventral nerve cord neurons; vem-1 interacts genetically with unc-40, whose protein product also interacts with VEM-1; a VEM-1::GFP reporter fusion is expressed from embryonic stages through late larval stages and is found in a subset of neurons, including the AVG pioneer neurons, that extend processes into the ventral nerve cord; microarray experiments indicate that vem-1 transcripts are upregulated in response to treatment with xenobiotics such as clofibrate and beta-naphthoflavone. | Paper_evidence | WBPaper00024484 | |||||
| WBPaper00026820 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 26 Feb 2009 00:00:00 | ||||||||
| Automated_description | Involved in innate immune response. Located in axon. Expressed in AVG; head neurons; and somatic nervous system. Is an ortholog of human PGRMC1 (progesterone receptor membrane component 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | K07E3.8 | |||||||
| Corresponding_CDS_history | K07E3.8a:wp252 | ||||||||
| Corresponding_transcript | K07E3.8.1 | ||||||||
| Other_sequence (28) | |||||||||
| Associated_feature | WBsf654188 | ||||||||
| WBsf654189 | |||||||||
| WBsf654190 | |||||||||
| WBsf654191 | |||||||||
| WBsf670808 | |||||||||
| WBsf982206 | |||||||||
| WBsf1006049 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00061111 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00050171 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00061112 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00016735 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr3106 | ||||||||
| Expr1011310 | |||||||||
| Expr1032922 | |||||||||
| Expr1153866 | |||||||||
| Expr2017966 | |||||||||
| Expr2036102 | |||||||||
| Drives_construct | WBCnstr00001989 | ||||||||
| WBCnstr00034111 | |||||||||
| Construct_product | WBCnstr00034111 | ||||||||
| Microarray_results (22) | |||||||||
| Expression_cluster (157) | |||||||||
| Interaction (20) | |||||||||
| Map_info | Map | X | Position | -0.581887 | Error | 0.008927 | |||
| Positive | Positive_clone | K07E3 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4259 | |||||||
| 4404 | |||||||||
| 4750 | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00018032 | ||||||||
| WBPaper00024484 | |||||||||
| WBPaper00026820 | |||||||||
| WBPaper00033099 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00048021 | |||||||||
| WBPaper00050498 | |||||||||
| WBPaper00055090 | |||||||||
| Remark | Sequence connection from [Runko E, Kaprielian Z] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
