WormBase Tree Display for Gene: WBGene00006856
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| WBGene00006856 | SMap | S_parent | Sequence | CHROMOSOME_II | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | usp-14 | |||||||
| Sequence_name | C13B4.2 | ||||||||
| Molecular_name | C13B4.2 | ||||||||
| C13B4.2.1 | |||||||||
| CE15615 | |||||||||
| Other_name | CELE_C13B4.2 | Accession_evidence | NDB | BX284602 | |||||
| Public_name | usp-14 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:43 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | usp | ||||||||
| Allele (61) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (12) | |||||||||
| Ortholog (35) | |||||||||
| Paralog (19) | |||||||||
| Structured_description | Concise_description | usp-14 encodes a homolog of ubiquitin-specific protease 14 (Usp14), a highly conserved thiol protease that hydrolyzes the peptide bond at the C-terminal glycine of ubiquitin (OMIM:607274, mutations are associated with synaptic defects in ataxia mice); by homology, USP-14 is predicted to function in ubiquitin-mediated protein degradation, or regulation of protein localization or activity; as loss of USP-14 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of USP-14 in C. elegans development and/or behavior is not yet known. | Paper_evidence | WBPaper00004540 | |||||
| WBPaper00004651 | |||||||||
| WBPaper00013147 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable cysteine-type deubiquitinase activity and proteasome binding activity. Predicted to be involved in regulation of proteasomal protein catabolic process. Predicted to be part of proteasome complex. Is an ortholog of human USP14 (ubiquitin specific peptidase 14). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | C13B4.2 | |||||||
| Corresponding_transcript | C13B4.2.1 | ||||||||
| Other_sequence (61) | |||||||||
| Associated_feature | WBsf650752 | ||||||||
| WBsf990727 | |||||||||
| WBsf224279 | |||||||||
| WBsf224280 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00002333 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00040414 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00027633 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00007535 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr12967 | ||||||||
| Expr1023870 | |||||||||
| Expr1032905 | |||||||||
| Expr1144483 | |||||||||
| Expr2017934 | |||||||||
| Expr2036070 | |||||||||
| Drives_construct | WBCnstr00034121 | ||||||||
| Construct_product | WBCnstr00034121 | ||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (156) | |||||||||
| Interaction (118) | |||||||||
| Map_info | Map | II | Position | 23.0229 | Error | 0.00229 | |||
| Positive | Positive_clone | C13B4 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 4590 | |||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00038491 | ||||||||
| WBPaper00049828 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00061750 | |||||||||
| WBPaper00062966 | |||||||||
| Remark | C13B4.2 was previously tgt-1, but it has been agreed that this name is incorrect and actively misleading, hence the change [JAH][021204 ck1] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
