WormBase Tree Display for Gene: WBGene00006856

WBGene00006856 SMap: S_parent: Sequence: CHROMOSOME_II
  Identity: Version: 1
    Name: CGC_name: usp-14
      Sequence_name: C13B4.2
      Molecular_name: C13B4.2
        C13B4.2.1
        CE15615
      Other_name: CELE_C13B4.2 Accession_evidence: NDB BX284602
      Public_name: usp-14
    DB_info: Database (12)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:43 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: usp
    Allele (61)
    RNASeq_FPKM (74)
    GO_annotation (12)
    Ortholog: WBGene00072082 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00024285 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00120565 Caenorhabditis japonica From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00162622 Caenorhabditis brenneri From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00107194 Pristionchus pacificus From_analysis: OMA
            WormBase-Compara
      WBGene00234180 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g7703 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g7553 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g5082 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g440 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP31.g26815 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g11388 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g9325 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g7465 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g9055 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_09127.g21896 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-usp-14 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold629.g8692 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_03181.g29330 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_04665 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_004869 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g01666 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g22332 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_20166600 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrII_pilon.g6541 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00213364 Caenorhabditis japonica From_analysis: WormBase-Compara
      WBGene00238967 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00264256 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00288515 Trichuris muris From_analysis: WormBase-Compara
      SGD:S000001906 Saccharomyces cerevisiae From_analysis: Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      FB:FBgn0032216 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-030131-7676 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:12612 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:1928898 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:1311825 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
    Paralog (19)
    Structured_description: Concise_description: usp-14 encodes a homolog of ubiquitin-specific protease 14 (Usp14), a highly conserved thiol protease that hydrolyzes the peptide bond at the C-terminal glycine of ubiquitin (OMIM:607274, mutations are associated with synaptic defects in ataxia mice); by homology, USP-14 is predicted to function in ubiquitin-mediated protein degradation, or regulation of protein localization or activity; as loss of USP-14 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of USP-14 in C. elegans development and/or behavior is not yet known. Paper_evidence: WBPaper00004540
            WBPaper00004651
            WBPaper00013147
          Curator_confirmed: WBPerson1843
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable cysteine-type deubiquitinase activity and proteasome binding activity. Predicted to be involved in regulation of proteasomal protein catabolic process. Predicted to be part of proteasome complex. Is an ortholog of human USP14 (ubiquitin specific peptidase 14). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: C13B4.2
    Corresponding_transcript: C13B4.2.1
    Other_sequence (61)
    Associated_feature: WBsf650752
      WBsf990727
      WBsf224279
      WBsf224280
  Experimental_info: RNAi_result: WBRNAi00002333 Inferred_automatically: RNAi_primary
      WBRNAi00040414 Inferred_automatically: RNAi_primary
      WBRNAi00027633 Inferred_automatically: RNAi_primary
      WBRNAi00007535 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr12967
      Expr1023870
      Expr1032905
      Expr1144483
      Expr2017934
      Expr2036070
    Drives_construct: WBCnstr00034121
    Construct_product: WBCnstr00034121
    Microarray_results (20)
    Expression_cluster (156)
    Interaction (118)
  Map_info: Map: II Position: 23.0229 Error: 0.00229
    Positive: Positive_clone: C13B4 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4590
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00049828
    WBPaper00055090
    WBPaper00061750
    WBPaper00062966
  Remark: C13B4.2 was previously tgt-1, but it has been agreed that this name is incorrect and actively misleading, hence the change [JAH][021204 ck1]
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene