WormBase Tree Display for Gene: WBGene00006856

WBGene00006856 SMap: S_parent: Sequence: CHROMOSOME_II
  Identity: Version: 1
    Name: CGC_name: usp-14
      Sequence_name: C13B4.2
      Molecular_name: C13B4.2
        C13B4.2.1
        CE15615
      Other_name: CELE_C13B4.2 Accession_evidence: NDB BX284602
      Public_name: usp-14
    DB_info: Database (12)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:43 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: usp
    Allele (61)
    RNASeq_FPKM (74)
    GO_annotation (12)
    Ortholog (35)
    Paralog (19)
    Structured_description: Concise_description: usp-14 encodes a homolog of ubiquitin-specific protease 14 (Usp14), a highly conserved thiol protease that hydrolyzes the peptide bond at the C-terminal glycine of ubiquitin (OMIM:607274, mutations are associated with synaptic defects in ataxia mice); by homology, USP-14 is predicted to function in ubiquitin-mediated protein degradation, or regulation of protein localization or activity; as loss of USP-14 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of USP-14 in C. elegans development and/or behavior is not yet known. Paper_evidence: WBPaper00004540
            WBPaper00004651
            WBPaper00013147
          Curator_confirmed: WBPerson1843
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable cysteine-type deubiquitinase activity and proteasome binding activity. Predicted to be involved in regulation of proteasomal protein catabolic process. Predicted to be part of proteasome complex. Is an ortholog of human USP14 (ubiquitin specific peptidase 14). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: C13B4.2
    Corresponding_transcript: C13B4.2.1
    Other_sequence (61)
    Associated_feature: WBsf650752
      WBsf990727
      WBsf224279
      WBsf224280
  Experimental_info: RNAi_result: WBRNAi00002333 Inferred_automatically: RNAi_primary
      WBRNAi00040414 Inferred_automatically: RNAi_primary
      WBRNAi00027633 Inferred_automatically: RNAi_primary
      WBRNAi00007535 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr12967
      Expr1023870
      Expr1032905
      Expr1144483
      Expr2017934
      Expr2036070
    Drives_construct: WBCnstr00034121
    Construct_product: WBCnstr00034121
    Microarray_results (20)
    Expression_cluster (156)
    Interaction: WBInteraction000102977
      WBInteraction000103613
      WBInteraction000103787
      WBInteraction000103864
      WBInteraction000104565
      WBInteraction000104645
      WBInteraction000105070
      WBInteraction000105139
      WBInteraction000105627
      WBInteraction000107208
      WBInteraction000107281
      WBInteraction000115455
      WBInteraction000121005
      WBInteraction000124918
      WBInteraction000124975
      WBInteraction000124989
      WBInteraction000125010
      WBInteraction000133157
      WBInteraction000133352
      WBInteraction000134624
      WBInteraction000135707
      WBInteraction000135972
      WBInteraction000137373
      WBInteraction000137749
      WBInteraction000143830
      WBInteraction000144641
      WBInteraction000144792
      WBInteraction000145714
      WBInteraction000150601
      WBInteraction000172610
      WBInteraction000178427
      WBInteraction000182773
      WBInteraction000185101
      WBInteraction000187669
      WBInteraction000190939
      WBInteraction000202625
      WBInteraction000204492
      WBInteraction000206987
      WBInteraction000222466
      WBInteraction000225900
      WBInteraction000233745
      WBInteraction000239606
      WBInteraction000240547
      WBInteraction000248724
      WBInteraction000254499
      WBInteraction000270897
      WBInteraction000273865
      WBInteraction000280957
      WBInteraction000280958
      WBInteraction000307519
      WBInteraction000317305
      WBInteraction000322154
      WBInteraction000334171
      WBInteraction000338244
      WBInteraction000345758
      WBInteraction000348422
      WBInteraction000349317
      WBInteraction000351220
      WBInteraction000354856
      WBInteraction000361212
      WBInteraction000370879
      WBInteraction000374991
      WBInteraction000377306
      WBInteraction000378747
      WBInteraction000379952
      WBInteraction000380216
      WBInteraction000382271
      WBInteraction000389616
      WBInteraction000391359
      WBInteraction000398725
      WBInteraction000405395
      WBInteraction000406101
      WBInteraction000408891
      WBInteraction000416804
      WBInteraction000422216
      WBInteraction000424665
      WBInteraction000424666
      WBInteraction000425376
      WBInteraction000432288
      WBInteraction000433055
      WBInteraction000435190
      WBInteraction000435191
      WBInteraction000437945
      WBInteraction000438819
      WBInteraction000448741
      WBInteraction000451504
      WBInteraction000463575
      WBInteraction000464778
      WBInteraction000464845
      WBInteraction000465544
      WBInteraction000466073
      WBInteraction000466767
      WBInteraction000466903
      WBInteraction000466904
      WBInteraction000467132
      WBInteraction000467150
      WBInteraction000467545
      WBInteraction000467735
      WBInteraction000469893
      WBInteraction000470019
      WBInteraction000470122
      WBInteraction000471025
      WBInteraction000471331
      WBInteraction000473085
      WBInteraction000474205
      WBInteraction000474219
      WBInteraction000475212
      WBInteraction000554527
      WBInteraction000563332
      WBInteraction000564765
      WBInteraction000565996
      WBInteraction000568706
      WBInteraction000571104
      WBInteraction000576062
      WBInteraction000577807
      WBInteraction000579345
      WBInteraction000580491
      WBInteraction000583157
  Map_info: Map: II Position: 23.0229 Error: 0.00229
    Positive: Positive_clone: C13B4 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4590
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00049828
    WBPaper00055090
    WBPaper00061750
    WBPaper00062966
  Remark: C13B4.2 was previously tgt-1, but it has been agreed that this name is incorrect and actively misleading, hence the change [JAH][021204 ck1]
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene