| WBGene00006825 | SMap | S_parent | Sequence | F13C5 |
|---|
| Identity | Version | 2 |
| | Name | CGC_name | unc-96 | Paper_evidence | WBPaper00027703 |
| | | | | Person_evidence | WBPerson261 |
| | | Sequence_name | F13C5.6 |
| | | Molecular_name | F13C5.6a |
| | | | F13C5.6a.1 |
| | | | CE27424 |
| | | | F13C5.6b |
| | | | CE29760 |
| | | | F13C5.6b.1 |
| | | Other_name | gei-10 | Person_evidence | WBPerson1796 |
| | | | CELE_F13C5.6 | Accession_evidence | NDB | BX284606 |
| | | Public_name | unc-96 |
| | DB_info | Database | AceView | gene | XB230 |
| | | | WormQTL | gene | WBGene00006825 |
| | | | WormFlux | gene | WBGene00006825 |
| | | | NDB | locus_tag | CELE_F13C5.6 |
| | | | NCBI | gene | 180413 |
| | | | RefSeq | protein | NM_171939.5 |
| | | | | | NM_171612.8 |
| | | | TREEFAM | TREEFAM_ID | TF316199 |
| | | | TrEMBL | UniProtAcc | O76566 |
| | | | | | H2KZR3 |
| | | | UniProt_GCRP | UniProtAcc | H2KZR3 |
| | Species | Caenorhabditis elegans |
| | History | Version_change | 1 | 07 Apr 2004 11:29:43 | WBPerson1971 | Event | Imported | Initial conversion from geneace |
| | | | 2 | 02 Feb 2007 10:15:15 | WBPerson2970 | Event | Acquires_merge | WBGene00001567 |
| | | | | | | Name_change | Other_name | gei-10 |
| | | Acquires_merge | WBGene00001567 |
| | Status | Live |
| Gene_info | Biotype | SO:0001217 |
| | Gene_class | unc |
| | Reference_allele | WBVar00248853 |
| | Allele (153) |
| | Legacy_information | su151 : very slightly slow slightly Egl moves well; abnormal muscle birefringence and ultrastruture collections of thin filaments near ends of cells. ES1 ME3. NA1. |
| | | [C.elegansII] su151 : very slightly slow, slightly Egl, moves well; abnormal muscle birefringence and ultrastructure, collections of thin filaments near ends of cells. ES1 ME3. NA1. [Zengel and Epstein 1980; HE] |
| | Strain | WBStrain00007703 |
| | | WBStrain00008393 |
| | RNASeq_FPKM (74) |
| | GO_annotation (14) |
| | Ortholog (27) |
| | Structured_description | Concise_description | unc-96 encodes a novel protein with no recognizable domains; unc-96 was identified in screens for mutations that disrupt body wall muscle cell structure and is required for muscle thick filament assembly, maintenance of muscle organization in response to muscle contraction, and normal locomotion; mutations in unc-96 interact genetically with mutations in unc-54, unc-98, unc-15, and unc-105, which encode a muscle-specific myosin heavy chain, zinc finger protein, paramyosin, and degenerin, respectively; in addition, UNC-96 physically interacts with UNC-98 and UNC-15, the latter of which is required for proper UNC-96 localization in body wall muscle; UNC-96 is found in body wall, pharyngeal, and anal depressor muscles; UNC-96 copurifies with thick filaments; antibody staining indicates that UNC-96 localizes to M-lines, while GFP tagging indicates that UNC-96 localizes to both M-lines and dense bodies. | Paper_evidence | WBPaper00000488 |
| | | | | | WBPaper00005938 |
| | | | | | WBPaper00027703 |
| | | | | Curator_confirmed | WBPerson1843 |
| | | | | Date_last_updated | 31 Jul 2007 00:00:00 |
| | | Automated_description | Enables myosin binding activity. Involved in locomotion; regulation of cytoskeleton organization; and striated muscle myosin thick filament assembly. Located in M band and striated muscle myosin thick filament. Expressed in anal depressor muscle; body wall musculature; and pharyngeal muscle cell. | Paper_evidence | WBPaper00065943 |
| | | | | Curator_confirmed | WBPerson324 |
| | | | | | WBPerson37462 |
| | | | | Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase |
| | | | | Date_last_updated | 29 Nov 2023 00:00:00 |
| Molecular_info | Corresponding_CDS | F13C5.6a |
| | | F13C5.6b |
| | Corresponding_transcript | F13C5.6a.1 |
| | | F13C5.6b.1 |
| | Other_sequence (22) |
| | Associated_feature (12) |
| Experimental_info | RNAi_result (15) |
| | Expr_pattern | Expr7859 |
| | | Expr7860 |
| | | Expr7861 |
| | | Expr1021808 |
| | | Expr1032889 |
| | | Expr1148443 |
| | | Expr2017922 |
| | | Expr2036058 |
| | Drives_construct | WBCnstr00012957 |
| | | WBCnstr00034134 |
| | Construct_product | WBCnstr00012957 |
| | | WBCnstr00034134 |
| | Antibody | WBAntibody00001112 |
| | Microarray_results (24) |
| | Expression_cluster | WBPaper00031040:TGF-beta_adult_upregulated |
| | | WBPaper00032425:up_in_zfp-1 |
| | | WBPaper00036375:enriched_in_PVD_OLL |
| | | WBPaper00037047:insoluble_protein |
| | | WBPaper00037055:DAF-16_binding_DNA |
| | | WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray |
| | | WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray |
| | | WBPaper00042215:wdr-23(tm1817)_upregulated |
| | | WBPaper00042561:smgl-1(RNAi)_upregulated |
| | | WBPaper00044037:eat-2_upregulated |
| | | WBPaper00044736:flat_dev_expression |
| | | WBPaper00044786:lem-2(tm1582)_upregulated |
| | | WBPaper00045314:S.aureus-induced_N2 |
| | | WBPaper00045521:Spermatogenic |
| | | WBPaper00046121:mesoderm_unique |
| | | WBPaper00046497:B.thuringiensis_upregulated_protein |
| | | WBPaper00047131:daf-2(e1370)_upregulated_N2-background |
| | | WBPaper00047132:glp-1(ts)-25C_upregulated |
| | | WBPaper00048988:neuron_expressed |
| | | WBPaper00049545:jmjd-3.1(+)_upregulated |
| | | WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated |
| | | WBPaper00049920:Glucose-Diet_upregulated_hyl-2(tm2031) |
| | | WBPaper00049920:Glucose-Diet_upregulated_N2 |
| | | WBPaper00050053:muscle_enriched_Day4 |
| | | WBPaper00050488:adult_vs_dauer_regulated_N2_20C |
| | | WBPaper00050726:OsmoticStress_regulated_Food |
| | | WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult |
| | | WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult |
| | | WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult |
| | | WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult |
| | | WBPaper00050990:body-muscle_expressed |
| | | WBPaper00050990:GABAergic-neuron_expressed |
| | | WBPaper00050990:pharynx_expressed |
| | | WBPaper00051245:cytoplasm_specific |
| | | WBPaper00051245:pharyngeal-muscle_cytoplasm_expressed |
| | | WBPaper00052884:emb-4(hc60)_upregulated |
| | | WBPaper00053184:sma-2(rax5)_upregulated |
| | | WBPaper00053184:sma-4(rax3)_upregulated |
| | | WBPaper00053302:alovudine_72h_regulated |
| | | WBPaper00053302:stavudine_24h_regulated |
| | | WBPaper00053302:zidovudine_72h_regulated |
| | | WBPaper00053388:dauer_regulated_Cluster1 |
| | | WBPaper00053599:oocyte_vs_mitosis_downregulated |
| | | WBPaper00053810:nuo-6(qm200)_upregulated |
| | | WBPaper00055354:eat-2(ad1116)_upregulated |
| | | WBPaper00055354:Psora-Allantoin_upregulated |
| | | WBPaper00055354:Rapamycin-Metformin_upregulated |
| | | WBPaper00055354:Rapamycin-Psora-Allantoin_upregulated |
| | | WBPaper00055354:Rapamycin-Rifampicin-Allantoin_upregulated |
| | | WBPaper00055354:Rapamycin-Rifampicin-Psora_upregulated |
| | | WBPaper00055354:Rapamycin-Rifampicin_upregulated |
| | | WBPaper00055354:Rifampicin-Allantoin_upregulated |
| | | WBPaper00055354:Rifampicin-Psora_upregulated |
| | | WBPaper00055354:Rifampicin_upregulated |
| | | WBPaper00055482:pmt-2(RNAi)_upregulated |
| | | WBPaper00055626:pry-1(mu38)_downregulated |
| | | WBPaper00056034:pals-22(jy3)_upregulated |
| | | WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047) |
| | | WBPaper00056169:rrf-3(pk1426)_upregulated_embryo |
| | | WBPaper00056284:ints-1(RNAi)_downregulated |
| | | WBPaper00056284:ints-11(RNAi)_downregulated |
| | | WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated |
| | | WBPaper00056471:S.aureus-4h_upregulated_N2 |
| | | WBPaper00056826:hmc_biased |
| | | WBPaper00056868:P.aeruginosa_upregulated_smallRNA |
| | | WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C |
| | | WBPaper00057006:DietaryRestriction_upregulated |
| | | WBPaper00058598:mex-3(eu149)_upregulated |
| | | WBPaper00058598:sin-3(tm1276)_downregulated |
| | | WBPaper00061007:S.aquatilis_upregulated |
| | | WBPaper00061203:sin-3(tm1276)_upregulated |
| | | WBPaper00061203:spr-1(ok2144)_upregulated |
| | | WBPaper00061340:AFD |
| | | WBPaper00061340:BWM_anterior |
| | | WBPaper00061340:DVC_parent |
| | | WBPaper00061340:mu_sph |
| | | WBPaper00061340:PLM |
| | | WBPaper00061340:PLM_ALN_grandparent |
| | | WBPaper00061479:hda-1(ne4752)_upregulated |
| | | WBPaper00061527:myo-3-Y71G12B.11_22540 |
| | | WBPaper00061527:rgs-2_11061-pde-1 |
| | | WBPaper00061818:ELKS-1_interacting |
| | | WBPaper00061995:mter-4(syb3662syb3403)_downregulated |
| | | WBPaper00062159:hda-2(ok1479)_upregulated |
| | | WBPaper00062193:hsf-1(RNAi)_upregulated |
| | | WBPaper00062193:skn-1(RNAi)_upregulated |
| | | WBPaper00062325:etr-1(lq61)_upregulated |
| | | WBPaper00062325:muscle_enriched_coding-RNA |
| | | WBPaper00064071:NHR-49_interacting |
| | | WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20) |
| | | WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20) |
| | | WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141) |
| | | WBPaper00064107:lin-35(n745)_downregulated |
| | | WBPaper00064306:Agaro-oligosaccharides_upregulated |
| | | WBPaper00064315:mrg-1(qa6200)_upregulated_PGCs |
| | | WBPaper00064716:paraquat_downregulated |
| | | WBPaper00064721:fasn-1(g14)_downregulated_starved |
| | | WBPaper00064769:him-17(me24)_upregulated |
| | | WBPaper00064871:hypoxia_downregulated_F1 |
| | | WBPaper00065096:Day10_vs_Day1_downregulated |
| | | WBPaper00065149:lin-52(n771)_downregulated |
| | | WBPaper00065581:hpk-1(pk1393)_upregulated |
| | | WBPaper00065835:Day5_vs_Day1_downregulated |
| | | WBPaper00065841:1_1 |
| | | WBPaper00065841:7_0 |
| | | WBPaper00065841:7_3 |
| | | WBPaper00065841:24_0 |
| | | WBPaper00065841:26_0 |
| | | WBPaper00065841:26_1 |
| | | WBPaper00065841:38_1 |
| | | WBPaper00065841:61_0 |
| | | WBPaper00065841:143_0 |
| | | WBPaper00065975:P-body_vs_oocyte_depleted |
| | | WBPaper00065975:P-body_vs_WholeAnimal_depleted |
| | | WBPaper00065993:glp-1(e2141)_upregulated |
| | | WBPaper00066038:mip-1(how5)_upregulated |
| | | WBPaper00066110:tetraploid_vs_diploid_upregulated |
| | | WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14 |
| | | cgc4386_cluster_3_5 |
| | | cgc4489_group_16 |
| | | cgc4489_group_20 |
| | | WBPaper00005124:estrogen_10-5M_regulated |
| | | WBPaper00025141:N2_Expressed_Genes |
| | | WBPaper00025141:unc-4::GFP_Expressed_Genes |
| | | WBPaper00031003:0hr_muscle_enriched |
| | | WBPaper00031003:24hr_muscle_enriched |
| | | WBPaper00031003:hlh_1_enriched |
| | | WBPaper00031003:total_muscle_enriched |
| | | WBPaper00031832:slr-2_regulated |
| | | WBPaper00035873:dpy-9_regulated |
| | | WBPaper00035873:dpy-10_regulated |
| | | WBPaper00035873:osm-8_regulated |
| | | WBPaper00035905:FBF-1_Associated |
| | | WBPaper00036123:Atrazine_regulated |
| | | WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2 |
| | | WBPaper00040963:Q100_down |
| | | WBPaper00041002:HQ_3d_2.0mM_Up |
| | | WBPaper00041174:environmental |
| | | WBPaper00041174:environmental_prime |
| | | WBPaper00041939:control_vs_UVC-EtBr-exposed_48h |
| | | WBPaper00047070:N2_starvation_upregulated |
| | | WBPaper00048989:N2_allantoin_downregulated |
| | | WBPaper00053236:Starvation_regulated_GR1307 |
| | | WBPaper00053236:Starvation_regulated_N2 |
| | | WBPaper00057098:SiO2-nanoparticles_upregulated |
| | | [cgc5376]:let-60(G12V)-regulated_genes |
| | Interaction (31) |
| Map_info | Map | X | Position | -19.557 | Error | 0.643684 |
| | Positive | Positive_clone | F13C5 | Inferred_automatically | From sequence, transcript, pseudogene data |
| | Mapping_data | 2_point | 395 |
| | | Multi_point | 313 |
| | | | 4495 |
| | | | 5271 |
| | | | 5713 |
| Reference (22) |
| Method | Gene |
