WormBase Tree Display for Gene: WBGene00006759

WBGene00006759 SMap: S_parent: Sequence: CHROMOSOME_IV
  Identity: Version: 3
    Name: CGC_name: unc-22 Person_evidence: WBPerson261
      Sequence_name: ZK617.1
      Molecular_name (27)
      Other_name: twitchin kinase Paper_evidence: WBPaper00002642
        twitchin Paper_evidence: WBPaper00031595
        CELE_ZK617.1 Accession_evidence: NDB BX284604
      Public_name: unc-22
    DB_info: Database (15)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:42 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 23 Feb 2010 15:11:48 WBPerson4025 Event: Acquires_merge: WBGene00014010
        3 02 Mar 2018 11:09:16 WBPerson4025 Event: Split_into: WBGene00303099
      Acquires_merge: WBGene00014010
      Split_into: WBGene00303099
    Status: Live
  Gene_info (11)
  Disease_info: Potential_model: DOID:0111188 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:12403)
      DOID:0110430 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:12403)
      DOID:0110283 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:12403)
      DOID:0111078 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:12403)
      DOID:0110315 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:12403)
      DOID:0081341 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:12403)
      DOID:12930 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:12403)
      DOID:3393 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:12403)
  Molecular_info: Corresponding_CDS: ZK617.1a
      ZK617.1b
      ZK617.1c
      ZK617.1d
      ZK617.1e
      ZK617.1f
      ZK617.1g
      ZK617.1h
      ZK617.1i
    Corresponding_CDS_history: ZK617.1a:wp92
      ZK617.1b:wp92
      ZK617.1c:wp229
      ZK617.1d:wp243
      ZK617.1j:wp264
    Corresponding_transcript: ZK617.1a.1
      ZK617.1b.1
      ZK617.1c.1
      ZK617.1d.1
      ZK617.1e.1
      ZK617.1f.1
      ZK617.1g.1
      ZK617.1h.1
      ZK617.1i.1
    Other_sequence (86)
    Associated_feature (32)
  Experimental_info: RNAi_result (41)
    Expr_pattern: Expr13345
      Expr13346
      Expr13347
      Expr13348
      Expr1013173
      Expr1032832
      Expr1162974
      Expr2017855
      Expr2035991
    Drives_construct: WBCnstr00039209
      WBCnstr00039210
      WBCnstr00039211
      WBCnstr00039212
    Construct_product: WBCnstr00001720
      WBCnstr00001721
      WBCnstr00001722
      WBCnstr00001723
      WBCnstr00001724
      WBCnstr00015909
    Antibody: WBAntibody00001511
      WBAntibody00001778
    Microarray_results (53)
    Expression_cluster: WBPaper00027339:daf-12(rh273)_upregulated
      WBPaper00028451:Oogenic_protein
      WBPaper00033065:clk-1(qm30)_upregulated
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00037055:DAF-16_binding_DNA
      WBPaper00038438:D.coniospora_12hr_downregulated_RNAseq
      WBPaper00038438:E.faecalis_24hr_upregulated_RNAseq
      WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
      WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
      WBPaper00040209:B.thuringiensis_upregulated_MY15
      WBPaper00040285:H2S_12hr_downregulated
      WBPaper00040285:H2S_24hr_downregulated
      WBPaper00042561:smgl-1(RNAi)_upregulated
      WBPaper00043951:insoluble_protein_day16_N2
      WBPaper00044426:rotenone_24h_downregulated
      WBPaper00044578:reduced-humidity_downregulated_microarray
      WBPaper00044736:flat_dev_expression
      WBPaper00044746:aging_downregulated_HeatShock
      WBPaper00045314:S.aureus-induced_hlh-30(tm1978)
      WBPaper00045390:tunicamycin_downregulated
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045693:S.flexneri_upregulated
      WBPaper00045971:tunicamycin_upregulated_control
      WBPaper00046446:rapid-synthesized_AgingAdult
      WBPaper00046446:slow-synthesized_YoungAdult
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00046795:starvation_upregulated
      WBPaper00047131:daf-2(e1370)_upregulated_hel-1(gk148684)-background
      WBPaper00047131:daf-2(e1370)_upregulated_N2-background
      WBPaper00048988:neuron_expressed
      WBPaper00049377:MWCNT_upregulated
      WBPaper00049920:Glucose-Diet_upregulated_N2
      WBPaper00049920:hyl-2(tm2031)_upregulated
      WBPaper00049942:hsf-1(RNAi)_upregulated
      WBPaper00049954:BPS_downregulated
      WBPaper00050015:ifg-1(RNAi)_upregulated
      WBPaper00050053:muscle_enriched_Day4
      WBPaper00050163:chd-3(eh4)_downregulated_24-cell-embryo
      WBPaper00050163:chd-3(eh4)_downregulated_100-cell-embryo
      WBPaper00050488:20C_vs_25C_regulated_mir-34(OverExpression)_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_adult_20C
      WBPaper00050698:DEP-1_interacting
      WBPaper00050859:upregulated_glh-1(gk100)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day1-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00050990:seam_expressed
      WBPaper00051039:ash-2(RNAi)_regulated_intestine
      WBPaper00051245:body-wall-muscle_cytoplasm_expressed
      WBPaper00051245:body-wall-muscle_nucleus_expressed
      WBPaper00051245:cytoplasm_specific
      WBPaper00051245:pharyngeal-muscle_cytoplasm_expressed
      WBPaper00051555:atm-1(gk186)_regulated_protein
      WBPaper00051558:aging_regulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053302:alovudine_24h_regulated
      WBPaper00053318:Aging_downregulated_mRNA_N2
      WBPaper00053321:mes-4(RNAi)_downregulated_fed-L1_Truseq
      WBPaper00053321:PGCs_depleted_NuGen
      WBPaper00053388:dauer_regulated_Cluster1
      WBPaper00053814:15C_downregulated_PY79
      WBPaper00053888:drh-3(rrr2)_downregulated
      WBPaper00054189:P.aeruginosa_regulated_protein
      WBPaper00054493:hpl-2(tm1489)_upregulated
      WBPaper00055334:DLC-1_interacting
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055482:Tunicamycin_downregulated
      WBPaper00055626:pry-1(mu38)_downregulated
      WBPaper00055969:electromagnetic-field_downregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056161:male_enriched_siRNA
      WBPaper00056275:P.aeruginosa_downregulated
      WBPaper00056275:P.aeruginosa_downregulated_atf-7(qd22qd130)_dependent
      WBPaper00056275:P.aeruginosa_downregulated_pmk-1(km25)_dependent
      WBPaper00056443:DietaryRestriction_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00056826:hmc_biased
      WBPaper00056868:P.aeruginosa_upregulated_smallRNA
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057154:HeatShock_downregulated_miRNA-target
      WBPaper00057154:HeatShock_upregulated_mRNA
      WBPaper00058598:mex-1(or286)_upregulated
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058598:spn-4(tm291)_upregulated
      WBPaper00058711:paraquat_upregulated
      WBPaper00058711:wdr-5(ok1417)_upregulated
      WBPaper00058725:sftb-1(cer39)_downregulated
      WBPaper00059027:neuron-synapses_enriched
      WBPaper00059231:alh-6(lax105)_D3Adult_upregulated
      WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
      WBPaper00059566:wdr-23(mac32)_upregulated
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059824:rnp-6(dh1127)_regulated_OP50
      WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
      WBPaper00059839:S.maltophilia_regulated
      WBPaper00059987:Wounding_upregulated
      WBPaper00060014:set-2(tm1630)_downregulated
      WBPaper00060358:B.thuringiensis_non-pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060399:pqm-1(ok485)_upregulated_CoCl2_6hr
      WBPaper00060526:plp-1(ok2155)_upregulated
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00060683:hlh-11(ko1)_upregulated
      WBPaper00060871:M.humicola-extract_4h_regulated
      WBPaper00060908:TEBP-1_interacting
      WBPaper00060908:TEBP-2_interacting
      WBPaper00061040:FW1256_upregulated
      WBPaper00061203:let-418(n3536)_upregulated
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061377:MYRF-1_interacting
      WBPaper00061390:daf-22(ok693)_ascarosides_upregulated
      WBPaper00061466:nath-10(icb99)_upregulated
      WBPaper00061466:nath-10(icb102)_upregulated
      WBPaper00061479:hda-1(ne4752)_upregulated
      WBPaper00061527:F49E2.5_8378-anc-1_2769
      WBPaper00061527:tnt-4-myo-1_2160
      WBPaper00061753:csr-1(tor159)_upregulated_25C
      WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
      WBPaper00062156:jmjd-5(zr1234)_upregulated
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062167:mbl-1(tm1563)_downregulated
      WBPaper00062325:etr-1(lq61)_downregulated
      WBPaper00062325:etr-1(lq61)_upregulated
      WBPaper00062440:crh-1(n3315)_upregulated
      WBPaper00062554:MAGU-2_interacting
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064055:trl-1(cas1077)_upregulated_non-starved
      WBPaper00064055:trl-1(cas1077)_upregulated_starved
      WBPaper00064055:trl-1(cas1078)_upregulated_starved
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064107:lin-35(n745)_upregulated
      WBPaper00064122:vulva_transcriptome
      WBPaper00064156:lbp-3(overexpress)_upregulated
      WBPaper00064229:B.thuringiensis-Cry5Ba_upregulated
      WBPaper00064306:Agaro-oligosaccharides_upregulated
      WBPaper00064624:iHg-induced_aggregome
      WBPaper00064716:paraquat_downregulated
      WBPaper00064727:daf-2(e1370)_upregulated
      WBPaper00064769:him-17(me24)_upregulated
      WBPaper00064933:bcf-1(ylf1)_upregulated_transcript
      WBPaper00064939:vit-5(RNAi)_upregulated
      WBPaper00065086:JU1400_N.ferruginous_regulated
      WBPaper00065086:N2_N.ferruginous_regulated
      WBPaper00065096:25C_vs_20C_downregulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065149:lin-52(n771)_downregulated
      WBPaper00065158:25C_vs_15C_downregulated_WholeAnimal
      WBPaper00065225:nhr-42(tm1375)_upregulated_S.aureus-infected
      WBPaper00065258:anchor-cell_depleted
      WBPaper00065373:Cisplatin_upregulated_WT
      WBPaper00065581:hpk-1(pk1393)_upregulated
      WBPaper00065623:53
      WBPaper00065623:97
      WBPaper00065835:Day5_vs_Day1_downregulated
      WBPaper00065835:Day11_vs_Day1_downregulated
      WBPaper00065841:1_1
      WBPaper00065841:4_0
      WBPaper00065841:4_1
      WBPaper00065841:4_2
      WBPaper00065841:7_0
      WBPaper00065841:7_1
      WBPaper00065841:7_2
      WBPaper00065841:7_3
      WBPaper00065841:7_4
      WBPaper00065841:24_1
      WBPaper00065841:26_0
      WBPaper00065841:38_0
      WBPaper00065841:38_1
      WBPaper00065841:38_2
      WBPaper00065841:38_3
      WBPaper00065841:102_0
      WBPaper00065841:110_0
      WBPaper00065841:143_0
      WBPaper00065975:P-body_vs_oocyte_depleted
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00065995:M.humicola-extract_downregulated_old-1(ok1273)
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      cgc4489_group_20
      WBPaper00024671:AFD_AWB_vs_unsorted_downregulated
      WBPaper00025141:unc-4::GFP_Enriched_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00030839:Embryo_A_Class
      WBPaper00031003:0hr_muscle_enriched
      WBPaper00031003:24hr_muscle_enriched
      WBPaper00031003:total_muscle_enriched
      WBPaper00031252:AIN-1_IP_enriched
      WBPaper00031532:Larva_Pan_Neuronal_Depleted
      WBPaper00031832:slr-2_regulated
      WBPaper00034661:AgNPs_downregulated
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.5
      WBPaper00040858:eQTL_age_regulated_developing
      WBPaper00041906:I-3690_vs_OP50_3d
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_EtBr-exposed_51h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-exposed_48h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_48h
      WBPaper00042331:a-SWCNTs_downregulated
      WBPaper00045263:0.1mM-paraquat_upregulated
      WBPaper00045263:nuo-6(qm200)_upregulated
      WBPaper00045865:biofilm_downregulated_B
      WBPaper00046853:AOBr_M.aeruginosa-batch-culture_downregulated
      WBPaper00047070:xpa-1_UV_downregulated
      WBPaper00048989:eat-2(ad465)_downregulated_in-DMSO
      WBPaper00049311:AgNO3_regulated
      WBPaper00049311:sAg-MNP_regulated
      WBPaper00051387:Triclosan_upregulated
      [cgc6390]:Cluster_C
    Interaction (67)
  Map_info: Map: IV Position: 5.45802 Error: 0.005203
    Well_ordered
    Positive: Inside_rearr: nDf28
        sDf8
      Positive_clone: LDM17
        YK1088
        ZK617 Inferred_automatically: From sequence, transcript, pseudogene data
    Negative: Outside_rearr: sDf22
        mDp4
    Mapping_data: 2_point (67)
      Multi_point (125)
      Pos_neg_data (38)
    Landmark_gene
  Reference (371)
  Remark: yk16f10.3 removed from sequence list. sdm 11/00
  Method: Gene