WormBase Tree Display for Gene: WBGene00006750
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WBGene00006750 | SMap | S_parent | Sequence | T10A3 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name | CGC_name | unc-10 | Person_evidence | WBPerson261 | |||||
Sequence_name | T10A3.1 | ||||||||
Molecular_name | T10A3.1a | ||||||||
T10A3.1a.1 | |||||||||
CE30169 | |||||||||
T10A3.1b | |||||||||
CE31234 | |||||||||
T10A3.1c | |||||||||
CE53614 | |||||||||
T10A3.1d | |||||||||
CE53668 | |||||||||
T10A3.1e | |||||||||
CE53500 | |||||||||
T10A3.1f | |||||||||
CE53547 | |||||||||
T10A3.1b.1 | |||||||||
T10A3.1c.1 | |||||||||
T10A3.1d.1 | |||||||||
T10A3.1e.1 | |||||||||
T10A3.1f.1 | |||||||||
Other_name | rim-1 | ||||||||
Rim | Paper_evidence | WBPaper00013595 | |||||||
CELE_T10A3.1 | Accession_evidence | NDB | BX284606 | ||||||
Public_name | unc-10 | ||||||||
DB_info | Database (11) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:41 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | unc | ||||||||
Reference_allele | WBVar00142961 | ||||||||
Allele (153) | |||||||||
Legacy_information | e102 : weak coiler tends to back loopy movement in reverse; fairly active slightly small and thin. ES3 ME2. NA2 (e126). | ||||||||
[C.elegansII] e102 : weak coiler, tends to back, loopy movement in reverse; fairly active; slightly small and thin; Ric. ES3 ME2. OA1: e126. [Brenner 1974; Nguyen et al. 1995] | |||||||||
[Nonet M] unc-10(e102) was phenotypically rescued by both cosmid C34H12 and a 16 kb BamHI/KpnI subclone of this cosmid that contains effectively only the rim-1 gene. The rim-1 gene (rim for Rab Interacting Molecule) is the combined genefinder products T10A3.1 and K03A1.3 (with several mistakes in the prediction by genefinder). Furthermore, unc-10(md330) and unc-10(md1117) both contain deletions of the vast majority of the rim-1 gene. Specifically, md1117 deleted 8.6 kb that extends from approximately 500 bp 5' of the atg to 200 bp 3' of the TAA of the rim-1 gene product. | |||||||||
[Nonet M] Encodes Rab-3 interacting protein. | |||||||||
Strain | WBStrain00002752 | ||||||||
WBStrain00027194 | |||||||||
WBStrain00029061 | |||||||||
WBStrain00004100 | |||||||||
WBStrain00005485 | |||||||||
WBStrain00005508 | |||||||||
WBStrain00005509 | |||||||||
WBStrain00051853 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (32) | |||||||||
Ortholog (51) | |||||||||
Structured_description | Concise_description | unc-10 encodes a protein with zinc-finger, Q/N-rich, PDZ, and C2 domains that is homologous to vertebrate Rim1, a presynaptic protein which binds, and effects the activity of, synaptic vesicle-associated GTP-Rab3; UNC-10 is required for normal locomotion and synaptic transmission, and localizes to a subdomain of presynaptic termini, where it probably acts to regulate the priming step of presynaptic vesicle fusion by promoting conformational changes in syntaxin. | Paper_evidence | WBPaper00002487 | |||||
WBPaper00004891 | |||||||||
WBPaper00005068 | |||||||||
WBPaper00012788 | |||||||||
WBPaper00012830 | |||||||||
WBPaper00012882 | |||||||||
WBPaper00012897 | |||||||||
WBPaper00013003 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
Automated_description | Enables small GTPase binding activity. Involved in several processes, including chemical synaptic transmission; defecation; and positive regulation of cholinergic synaptic transmission. Located in axon and presynaptic active zone. Expressed in dorsal nerve cord; nerve ring; nervous system; uv1; and ventral nerve cord. Is an ortholog of human RIMS1 (regulating synaptic membrane exocytosis 1). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | T10A3.1a | |||||||
T10A3.1b | |||||||||
T10A3.1c | |||||||||
T10A3.1d | |||||||||
T10A3.1e | |||||||||
T10A3.1f | |||||||||
Corresponding_transcript | T10A3.1a.1 | ||||||||
T10A3.1b.1 | |||||||||
T10A3.1c.1 | |||||||||
T10A3.1d.1 | |||||||||
T10A3.1e.1 | |||||||||
T10A3.1f.1 | |||||||||
Other_sequence (30) | |||||||||
Associated_feature (22) | |||||||||
Experimental_info | RNAi_result (19) | ||||||||
Expr_pattern | Chronogram1591 | ||||||||
Expr2418 | |||||||||
Expr14780 | |||||||||
Expr15235 | |||||||||
Expr15236 | |||||||||
Expr1017493 | |||||||||
Expr1032824 | |||||||||
Expr1156587 | |||||||||
Expr2017837 | |||||||||
Expr2035973 | |||||||||
Drives_construct | WBCnstr00003280 | ||||||||
WBCnstr00034173 | |||||||||
Construct_product (11) | |||||||||
Antibody | WBAntibody00000412 | ||||||||
WBAntibody00000866 | |||||||||
WBAntibody00001456 | |||||||||
WBAntibody00001656 | |||||||||
WBAntibody00001729 | |||||||||
WBAntibody00002171 | |||||||||
Microarray_results (30) | |||||||||
Expression_cluster (208) | |||||||||
Interaction (82) | |||||||||
Map_info | Map | X | Position | -1.7816 | Error | 0.001118 | |||
Well_ordered | |||||||||
Positive | Positive_clone | C34H12 | |||||||
T10A3 | Person_evidence | WBPerson451 | |||||||
Inferred_automatically | From sequence, transcript, pseudogene data | ||||||||
Mapping_data | 2_point | 147 | |||||||
182 | |||||||||
3912 | |||||||||
3913 | |||||||||
6198 | |||||||||
Multi_point (23) | |||||||||
Pos_neg_data (13) | |||||||||
Reference | WBPaper00000031 | ||||||||
WBPaper00000608 | |||||||||
WBPaper00001218 | |||||||||
WBPaper00001443 | |||||||||
WBPaper00001558 | |||||||||
WBPaper00001709 | |||||||||
WBPaper00002195 | |||||||||
WBPaper00002487 | |||||||||
WBPaper00002590 | |||||||||
WBPaper00004891 | |||||||||
WBPaper00005423 | |||||||||
WBPaper00005528 | |||||||||
WBPaper00005543 | |||||||||
WBPaper00006049 | |||||||||
WBPaper00010018 | |||||||||
WBPaper00010864 | |||||||||
WBPaper00011509 | |||||||||
WBPaper00013595 | |||||||||
WBPaper00013752 | |||||||||
WBPaper00013979 | |||||||||
WBPaper00014706 | |||||||||
WBPaper00014723 | |||||||||
WBPaper00014761 | |||||||||
WBPaper00014791 | |||||||||
WBPaper00015253 | |||||||||
WBPaper00015500 | |||||||||
WBPaper00015812 | |||||||||
WBPaper00016723 | |||||||||
WBPaper00017184 | |||||||||
WBPaper00018073 | |||||||||
WBPaper00019199 | |||||||||
WBPaper00019330 | |||||||||
WBPaper00022646 | |||||||||
WBPaper00023487 | |||||||||
WBPaper00023973 | |||||||||
WBPaper00024247 | |||||||||
WBPaper00024525 | |||||||||
WBPaper00025638 | |||||||||
WBPaper00026015 | |||||||||
WBPaper00026196 | |||||||||
WBPaper00026618 | |||||||||
WBPaper00026667 | |||||||||
WBPaper00026711 | |||||||||
WBPaper00026785 | |||||||||
WBPaper00026941 | |||||||||
WBPaper00027296 | |||||||||
WBPaper00027304 | |||||||||
WBPaper00027305 | |||||||||
WBPaper00027751 | |||||||||
WBPaper00028379 | |||||||||
WBPaper00028808 | |||||||||
WBPaper00028886 | |||||||||
WBPaper00030810 | |||||||||
WBPaper00030844 | |||||||||
WBPaper00030845 | |||||||||
WBPaper00030995 | |||||||||
WBPaper00031137 | |||||||||
WBPaper00031717 | |||||||||
WBPaper00032122 | |||||||||
WBPaper00032233 | |||||||||
WBPaper00032252 | |||||||||
WBPaper00032389 | |||||||||
WBPaper00034738 | |||||||||
WBPaper00035074 | |||||||||
WBPaper00035163 | |||||||||
WBPaper00035356 | |||||||||
WBPaper00035492 | |||||||||
WBPaper00036179 | |||||||||
WBPaper00037731 | |||||||||
WBPaper00038253 | |||||||||
WBPaper00038491 | |||||||||
WBPaper00039282 | |||||||||
WBPaper00041950 | |||||||||
WBPaper00043415 | |||||||||
WBPaper00043908 | |||||||||
WBPaper00044074 | |||||||||
WBPaper00045955 | |||||||||
WBPaper00048069 | |||||||||
WBPaper00048427 | |||||||||
WBPaper00052130 | |||||||||
WBPaper00052816 | |||||||||
WBPaper00055090 | |||||||||
WBPaper00055787 | |||||||||
WBPaper00056826 | |||||||||
WBPaper00057348 | |||||||||
WBPaper00057647 | |||||||||
WBPaper00057845 | |||||||||
WBPaper00058534 | |||||||||
WBPaper00059613 | |||||||||
WBPaper00061027 | |||||||||
WBPaper00061401 | |||||||||
WBPaper00061408 | |||||||||
WBPaper00061748 | |||||||||
WBPaper00061818 | |||||||||
WBPaper00062568 | |||||||||
WBPaper00063848 | |||||||||
WBPaper00063852 | |||||||||
WBPaper00064182 | |||||||||
WBPaper00064323 | |||||||||
WBPaper00064639 | |||||||||
WBPaper00064844 | |||||||||
WBPaper00064911 | |||||||||
WBPaper00064934 | |||||||||
WBPaper00064955 | |||||||||
WBPaper00065105 | |||||||||
WBPaper00065262 | |||||||||
WBPaper00065342 | |||||||||
WBPaper00065360 | |||||||||
Remark | Sequence connection from [Koushika SP, Nonet M] | ||||||||
Other name from JA Hodgkin, 09/02/2002 | |||||||||
unc-10 is the same as rim-1 and therefore rim-1 was merged into unc-10 based on advice from JAH | |||||||||
Method | Gene |