WormBase Tree Display for Gene: WBGene00006597

WBGene00006597 Evidence: CGC_data_submission
  SMap: S_parent: Sequence: Y37A1B
  Identity: Version: 1
    Name: CGC_name: tor-1 Person_evidence: WBPerson87
      Sequence_name: Y37A1B.12
      Molecular_name: Y37A1B.12
        Y37A1B.12.1
        CE43294
        Y37A1B.12.2
      Other_name: dyt-2
        CELE_Y37A1B.12 Accession_evidence: NDB BX284604
      Public_name: tor-1
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:41 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: tor
    Allele (39)
    Component_of_genotype: WBGenotype00000148
    RNASeq_FPKM (74)
    GO_annotation (14)
    Contained_in_operon: CEOP4572
    Ortholog: WBGene00114552 Pristionchus pacificus From_analysis: Inparanoid_8
            WormBase-Compara
      WBGene00040105 Caenorhabditis briggsae From_analysis: WormBase-Compara
      WBGene00226635 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g7249 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g11422 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g1906 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP31.g2196 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP38.g21053 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      Cang_2012_03_13_00342.g9464 Caenorhabditis angaria From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g02107 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g7162 Panagrellus redivivus From_analysis: WormBase-Compara
      chrIV_pilon.g12408 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00247797 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00264049 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00301557 Trichuris muris From_analysis: WormBase-Compara
      FB:FBgn0025615 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-040426-1859 Danio rerio From_analysis: EnsEMBL-Compara
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-121107-3 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-050913-60 Danio rerio From_analysis: EnsEMBL-Compara
            OMA
            OrthoFinder
            Panther
      ZFIN:ZDB-GENE-080917-50 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-081104-165 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-080723-36 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:3098 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:11995 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:11996 Homo sapiens From_analysis: Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:11997 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
      MGI:1353568 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      MGI:1353596 Mus musculus From_analysis: EnsEMBL-Compara
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:1353605 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:1353652 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoFinder
            Panther
      RGD:628863 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:1310101 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoFinder
            Panther
            PhylomeDB
      RGD:1308431 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:1359111 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
    Paralog: WBGene00003870 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00006598 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            Panther
            WormBase-Compara
    Structured_description: Concise_description: tor-1 encodes a AAA+ ATPase that, along with TOR-2 and OOC-5, comprise the three C. elegans orthologs of human TorsinA. Paper_evidence: WBPaper00005005
            WBPaper00005722
          Curator_confirmed: WBPerson1843
          Date_last_updated: 16 Jun 2008 00:00:00
      Automated_description: Predicted to enable ATP binding activity and ATP hydrolysis activity. Predicted to be involved in cellular response to misfolded protein. Predicted to be located in endoplasmic reticulum lumen. Expressed in anal depressor muscle; head mesodermal cell; head neurons; and intestinal muscle. Human ortholog(s) of this gene implicated in arthrogryposis multiplex congenita-5 and torsion dystonia 1. Is an ortholog of human TOR1A (torsin family 1 member A) and TOR1B (torsin family 1 member B). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0080981 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:3098)
      DOID:0060730 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:3098)
  Modifies_disease: DOID:10652
  Modifies_disease_in_annotation: WBDOannot00000218
  Molecular_info: Corresponding_CDS: Y37A1B.12
    Corresponding_CDS_history: Y37A1B.12:wp196
    Corresponding_transcript: Y37A1B.12.1
      Y37A1B.12.2
  Experimental_info: RNAi_result: WBRNAi00055848 Inferred_automatically: RNAi_primary
      WBRNAi00076762 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr11291
      Expr1020300
      Expr1159379
      Expr2017460
      Expr2035599
    Drives_construct: WBCnstr00018741
      WBCnstr00034281
    Construct_product: WBCnstr00034281
    Microarray_results (15)
    Expression_cluster (49)
    Interaction (31)
    WBProcess: WBbiopr:00000078
  Map_info: Map: IV Position: 11.0294 Error: 0.008674
    Positive: Positive_clone: Y37A1B Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00005005
    WBPaper00005722
    WBPaper00006152
    WBPaper00012397
    WBPaper00017955
    WBPaper00017956
    WBPaper00024947
    WBPaper00025671
    WBPaper00038491
    WBPaper00055090
  Remark: Sequence connection from [Caldwell GA]
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene