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WormBase Tree Display for Gene: WBGene00006593

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Name Class

WBGene00006593SMapS_parentSequenceCHROMOSOME_I
IdentityVersion1
NameCGC_nametol-1Person_evidenceWBPerson1122
Sequence_nameC07F11.1
Molecular_nameC07F11.1
C07F11.1.1
CE28818
Other_nameC07F11.aCurator_confirmedWBPerson1983
RemarkOld cosmid naming mapped via unique overlapping PCR_product on CDSs
C07F11.bCurator_confirmedWBPerson1983
RemarkOld cosmid naming mapped via unique overlapping PCR_product on CDSs
CELE_C07F11.1Accession_evidenceNDBBX284601
Public_nametol-1
DB_infoDatabaseAceViewgene1A933
WormQTLgeneWBGene00006593
WormFluxgeneWBGene00006593
NDBlocus_tagCELE_C07F11.1
PanthergeneCAEEL|WormBase=WBGene00006593|UniProtKB=Q9N5Z3
familyPTHR24373
NCBIgene171635
RefSeqproteinNM_001025812.6
TREEFAMTREEFAM_IDTF325595
TrEMBLUniProtAccQ9N5Z3
UniProt_GCRPUniProtAccQ9N5Z3
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:41WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classtol
Allele (303)
StrainWBStrain00007217
WBStrain00021957
WBStrain00021972
WBStrain00029108
RNASeq_FPKM (74)
GO_annotation00095698
00095699
00095700
00095701
00095702
00095703
00095704
00095705
00105846
00114408
Contained_in_operonCEOP1008
Ortholog (48)
ParalogWBGene00003915Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00008977Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00011971Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00020649Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00022789Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptiontol-1 encodes a predicted transmembrane protein that is the sole C. elegans Toll-like receptor (TLR); TOL-1 is required for proper embryonic development and for pathogen avoidance behavior, and is expressed primarily in the nervous system.Paper_evidenceWBPaper00004692
Curator_confirmedWBPerson1843
Date_last_updated28 Feb 2006 00:00:00
Automated_descriptionPredicted to enable signaling receptor activity. Involved in defense response to Gram-negative bacterium and embryo development. Predicted to be located in extracellular matrix and extracellular space. Expressed in neurons. Is an ortholog of several human genes including CHAD (chondroadherin); ELFN2 (extracellular leucine rich repeat and fibronectin type III domain containing 2); and TRIL (TLR4 interactor with leucine rich repeats).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSC07F11.1
Corresponding_CDS_historyC07F11.1b:wp115
Corresponding_transcriptC07F11.1.1
Other_sequence (20)
Associated_feature (24)
Experimental_infoRNAi_resultWBRNAi00112556Inferred_automaticallyRNAi_primary
WBRNAi00063081Inferred_automaticallyRNAi_primary
WBRNAi00082217Inferred_automaticallyRNAi_primary
WBRNAi00004994Inferred_automaticallyRNAi_primary
WBRNAi00040008Inferred_automaticallyRNAi_primary
WBRNAi00028638Inferred_automaticallyRNAi_primary
WBRNAi00116880Inferred_automaticallyRNAi_primary
Expr_patternExpr1361
Expr12434
Expr15432
Expr1027970
Expr1032726
Expr1144085
Expr2017451
Expr2035590
Drives_constructWBCnstr00010235
WBCnstr00021084
Construct_productWBCnstr00010235
WBCnstr00042643
WBCnstr00042645
Microarray_results (19)
Expression_cluster (133)
Interaction (23)
WBProcessWBbiopr:00000008
WBbiopr:00000039
Map_infoMapIPosition-19.0389Error0.00579
PositivePositive_cloneC07F11Inferred_automaticallyFrom sequence, transcript, pseudogene data
W05D2
Mapping_dataMulti_point4391
4732
4872
Pseudo_map_position
ReferenceWBPaper00003925
WBPaper00004692
WBPaper00005709
WBPaper00006488
WBPaper00006512
WBPaper00019611
WBPaper00023386
WBPaper00024209
WBPaper00025180
WBPaper00025183
WBPaper00026131
WBPaper00026689
WBPaper00026948
WBPaper00027295
WBPaper00029071
WBPaper00030989
WBPaper00031161
WBPaper00032445
WBPaper00032891
WBPaper00037382
WBPaper00038491
WBPaper00039409
WBPaper00041669
WBPaper00041897
WBPaper00042367
WBPaper00045112
WBPaper00046621
WBPaper00048436
WBPaper00049281
WBPaper00049748
WBPaper00049765
WBPaper00050250
WBPaper00052548
WBPaper00052593
WBPaper00053732
WBPaper00055090
WBPaper00055976
WBPaper00060200
WBPaper00060906
WBPaper00062938
WBPaper00064105
WBPaper00064255
WBPaper00064339
WBPaper00064805
WBPaper00065184
RemarkSequence connection from [Pujol N, Ewbank JJ] based on AF348166
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene