WormBase Tree Display for Gene: WBGene00006523
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| WBGene00006523 | SMap | S_parent | Sequence | F26G5 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | tam-1 | Person_evidence | WBPerson959 | |||||
| Sequence_name | F26G5.9 | ||||||||
| Molecular_name | F26G5.9 | ||||||||
| F26G5.9.1 | |||||||||
| CE09704 | |||||||||
| Other_name | CELE_F26G5.9 | Accession_evidence | NDB | BX284605 | |||||
| Public_name | tam-1 | ||||||||
| DB_info | Database | AceView | gene | 5F438 | |||||
| WormQTL | gene | WBGene00006523 | |||||||
| WormFlux | gene | WBGene00006523 | |||||||
| NDB | locus_tag | CELE_F26G5.9 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00006523|UniProtKB=G5ED20 | |||||||
| family | PTHR25462 | ||||||||
| NCBI | gene | 178887 | |||||||
| RefSeq | protein | NM_071934.7 | |||||||
| TREEFAM | TREEFAM_ID | TF350293 | |||||||
| TrEMBL | UniProtAcc | G5ED20 | |||||||
| UniProt_GCRP | UniProtAcc | G5ED20 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:40 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | tam | ||||||||
| Allele (125) | |||||||||
| Strain | WBStrain00030593 | ||||||||
| WBStrain00030594 | |||||||||
| WBStrain00030595 | |||||||||
| WBStrain00036992 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (11) | |||||||||
| Ortholog (24) | |||||||||
| Paralog | WBGene00003598 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WBGene00003599 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| Structured_description | Concise_description | tam-1 encodes a broadly expressed nuclear protein with RING finger, B-box, and glutamine/asparagine-rich domains that promotes signalling in the class B synthetic-multivulva gene pathway (which includes the lin-35/RB gene), and also promotes the activity of genes in multicopy transgenic arrays; the normal role of TAM-1's class B activity is presumably to inhibit RAS pathway activity in vulval development, while TAM-1's effect on transgenes may be through changes in the acetylation state of histones in chromatin; about 3% to 10% of tam-1 transcripts are RNA edited to change A to G resulting in a synonymous change to residue 784 from an L to a L. | Paper_evidence | WBPaper00003822 | |||||
| WBPaper00005068 | |||||||||
| WBPaper00012788 | |||||||||
| WBPaper00012830 | |||||||||
| WBPaper00012882 | |||||||||
| WBPaper00012897 | |||||||||
| WBPaper00013003 | |||||||||
| WBPaper00045975 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| WBPerson4025 | |||||||||
| Date_last_updated | 28 Dec 2012 00:00:00 | ||||||||
| Automated_description | Predicted to enable ubiquitin protein ligase activity. Involved in several processes, including chromosome segregation; negative regulation of vulval development; and transcription initiation-coupled chromatin remodeling. Located in germ cell nucleus. Expressed in several structures, including germ line. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F26G5.9 | |||||||
| Corresponding_transcript | F26G5.9.1 | ||||||||
| Other_sequence | FK804436.1 | ||||||||
| Hbac_isotig06648 | |||||||||
| HBC11786_1 | |||||||||
| EX014679.1 | |||||||||
| Associated_feature (18) | |||||||||
| Experimental_info | RNAi_result (21) | ||||||||
| Expr_pattern | Expr972 | ||||||||
| Expr2884 | |||||||||
| Expr3582 | |||||||||
| Expr1027851 | |||||||||
| Expr1032676 | |||||||||
| Expr1149610 | |||||||||
| Expr2017295 | |||||||||
| Expr2035430 | |||||||||
| Drives_construct | WBCnstr00034326 | ||||||||
| Construct_product | WBCnstr00011506 | ||||||||
| WBCnstr00034326 | |||||||||
| Antibody | WBAntibody00000256 | ||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (123) | |||||||||
| Interaction (106) | |||||||||
| Map_info | Map | V | Position | -3.66231 | Error | 0.003466 | |||
| Positive | Positive_clone | F26G5 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4514 | |||||||
| 4718 | |||||||||
| 5591 | |||||||||
| 5661 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (22) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
