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WormBase Tree Display for Gene: WBGene00006382

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Name Class

WBGene00006382SMapS_parentSequenceCHROMOSOME_I
IdentityVersion1
NameCGC_nametaf-1
Sequence_nameW04A8.7
Molecular_nameW04A8.7a
W04A8.7a.1
CE42634
W04A8.7b
CE54397
W04A8.7b.1
Other_nameY71A12B.bCurator_confirmedWBPerson1983
RemarkOld cosmid naming mapped via unique overlapping PCR_product on CDSs
CELE_W04A8.7Accession_evidenceNDBBX284601
Public_nametaf-1
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:40WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classtaf
Allele (397)
RNASeq_FPKM (74)
GO_annotation (23)
Contained_in_operonCEOP1728
Ortholog (42)
Structured_descriptionConcise_descriptionThe taf-1 gene encodes an ortholog of human TATA-binding protein associated factor TAF1L (TAFII250) that possesses histone acetyl transferase (HAT) activity and is a component of the TFIID general transcription factor that recognizes the transcription start site; TAF-1 is required for proper embryonic and larval development.Paper_evidenceWBPaper00004402
WBPaper00004890
WBPaper00005654
Curator_confirmedWBPerson1843
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable several functions, including RNA polymerase II general transcription initiation factor activity; TBP-class protein binding activity; and histone acetyltransferase activity. Predicted to contribute to transcription cis-regulatory region binding activity. Involved in embryo development and transcription initiation at RNA polymerase II promoter. Located in nucleus. Human ortholog(s) of this gene implicated in X-linked dystonia-parkinsonism and syndromic X-linked intellectual disability. Is an ortholog of human TAF1L (TATA-box binding protein associated factor 1 like).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0090057Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11535)
DOID:0060309Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11535)
Molecular_infoCorresponding_CDSW04A8.7a
W04A8.7b
Corresponding_CDS_historyW04A8.7:wp20
W04A8.7:wp191
Corresponding_transcriptW04A8.7a.1
W04A8.7b.1
Other_sequence (53)
Associated_featureWBsf643820
WBsf657050
WBsf985962
WBsf985963
WBsf985964
WBsf1011126
WBsf1011127
WBsf218758
Transcription_factorWBTranscriptionFactor000206
WBTranscriptionFactor000421
Experimental_infoRNAi_result (32)
Expr_patternExpr1027270
Expr1032579
Expr1158287
Expr2017211
Expr2035347
AntibodyWBAntibody00000731
Microarray_results (23)
Expression_cluster (114)
Interaction (177)
Map_infoMapIPosition22.0627Error0.064158
PositivePositive_cloneW04A8Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point4888
4903
5555
Pseudo_map_position
Reference (14)
RemarkSequence connection from [source: A Walker]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene