WormBase Tree Display for Gene: WBGene00006382
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WBGene00006382 | SMap | S_parent | Sequence | CHROMOSOME_I | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name | CGC_name | taf-1 | |||||||
Sequence_name | W04A8.7 | ||||||||
Molecular_name | W04A8.7a | ||||||||
W04A8.7a.1 | |||||||||
CE42634 | |||||||||
W04A8.7b | |||||||||
CE54397 | |||||||||
W04A8.7b.1 | |||||||||
Other_name | Y71A12B.b | Curator_confirmed | WBPerson1983 | ||||||
Remark | Old cosmid naming mapped via unique overlapping PCR_product on CDSs | ||||||||
CELE_W04A8.7 | Accession_evidence | NDB | BX284601 | ||||||
Public_name | taf-1 | ||||||||
DB_info | Database (11) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:40 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | taf | ||||||||
Allele (397) | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (23) | |||||||||
Contained_in_operon | CEOP1728 | ||||||||
Ortholog (42) | |||||||||
Structured_description | Concise_description | The taf-1 gene encodes an ortholog of human TATA-binding protein associated factor TAF1L (TAFII250) that possesses histone acetyl transferase (HAT) activity and is a component of the TFIID general transcription factor that recognizes the transcription start site; TAF-1 is required for proper embryonic and larval development. | Paper_evidence | WBPaper00004402 | |||||
WBPaper00004890 | |||||||||
WBPaper00005654 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
Automated_description | Predicted to enable several functions, including RNA polymerase II general transcription initiation factor activity; TBP-class protein binding activity; and histone acetyltransferase activity. Predicted to contribute to transcription cis-regulatory region binding activity. Involved in embryo development and transcription initiation at RNA polymerase II promoter. Located in nucleus. Human ortholog(s) of this gene implicated in X-linked dystonia-parkinsonism and syndromic X-linked intellectual disability. Is an ortholog of human TAF1L (TATA-box binding protein associated factor 1 like). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:0090057 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11535) | ||||
DOID:0060309 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11535) | ||||||
Molecular_info | Corresponding_CDS | W04A8.7a | |||||||
W04A8.7b | |||||||||
Corresponding_CDS_history | W04A8.7:wp20 | ||||||||
W04A8.7:wp191 | |||||||||
Corresponding_transcript | W04A8.7a.1 | ||||||||
W04A8.7b.1 | |||||||||
Other_sequence (53) | |||||||||
Associated_feature | WBsf643820 | ||||||||
WBsf657050 | |||||||||
WBsf985962 | |||||||||
WBsf985963 | |||||||||
WBsf985964 | |||||||||
WBsf1011126 | |||||||||
WBsf1011127 | |||||||||
WBsf218758 | |||||||||
Transcription_factor | WBTranscriptionFactor000206 | ||||||||
WBTranscriptionFactor000421 | |||||||||
Experimental_info | RNAi_result (32) | ||||||||
Expr_pattern | Expr1027270 | ||||||||
Expr1032579 | |||||||||
Expr1158287 | |||||||||
Expr2017211 | |||||||||
Expr2035347 | |||||||||
Antibody | WBAntibody00000731 | ||||||||
Microarray_results (23) | |||||||||
Expression_cluster (114) | |||||||||
Interaction (177) | |||||||||
Map_info | Map | I | Position | 22.0627 | Error | 0.064158 | |||
Positive | Positive_clone | W04A8 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Mapping_data | Multi_point | 4888 | |||||||
4903 | |||||||||
5555 | |||||||||
Pseudo_map_position | |||||||||
Reference (14) | |||||||||
Remark | Sequence connection from [source: A Walker] | ||||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
Method | Gene |