WormBase Tree Display for Gene: WBGene00005646

WBGene00005646 SMap: S_parent: Sequence: C03G6
  Identity: Version: 2
    Name: CGC_name: srp-5 Person_evidence: WBPerson1460
      Sequence_name: C03G6.18
      Molecular_name: C03G6.18
      Other_name: CELE_C03G6.18 Accession_evidence: NDB BX284605
      Public_name: srp-5
    DB_info: Database: AceView gene 5H860
        WormQTL gene WBGene00005646
        WormFlux gene WBGene00005646
        NDB locus_tag CELE_C03G6.18
        NCBI gene 191959
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:38 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 03 Sep 2014 17:01:34 WBPerson4025 Event: Changed_class: CDS Pseudogene
    Status: Live
  Gene_info: Biotype: SO:0000336
    Gene_class: srp
    Allele (22)
    RNASeq_FPKM (74)
    Ortholog: WBGene00151415 Caenorhabditis brenneri From_analysis: Inparanoid_8
      WBGene00145699 Caenorhabditis brenneri From_analysis: Inparanoid_8
      WBGene00142128 Caenorhabditis brenneri From_analysis: Inparanoid_8
      WBGene00219155 Caenorhabditis japonica From_analysis: Inparanoid_8
      WBGene00121162 Caenorhabditis japonica From_analysis: Inparanoid_8
      WBGene00080449 Caenorhabditis remanei From_analysis: Inparanoid_8
      WBGene00080563 Caenorhabditis remanei From_analysis: Inparanoid_8
      WBGene00080437 Caenorhabditis remanei From_analysis: Inparanoid_8
      WBGene00102097 Pristionchus pacificus From_analysis: Inparanoid_8
    Structured_description: Concise_description: srp-5 encodes an ovalbumin-like serpin (ov-serpin) member of the serine protease inhibitor superfamily; by homology, SRP-5 is predicted to function as a suicide substrate that inhibits the proteolytic activity of serine proteases; however, as loss of srp-5 function via RNA-mediated interference (RNAi) does not result in any obvious abnormalities, the precise role of SRP-5 in C. elegans development and/or behavior is not yet known. Paper_evidence: WBPaper00005654
            WBPaper00010613
            WBPaper00012880
            WBPaper00017560
          Curator_confirmed: WBPerson1843
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Enriched in body wall muscle cell and hypodermis based on tiling array studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray and RNA-seq studies. Is affected by Hydrolyzable Tannins; Humic Substances; and Sirolimus based on microarray studies. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS_history: C03G6.18:wp128
      C03G6.18:wp245
    Corresponding_pseudogene: C03G6.18
    Other_sequence (53)
  Experimental_info: Expr_pattern: Expr1022943
      Expr1143650
    Microarray_results (18)
    Expression_cluster: WBPaper00030922:glycosylated_protein
      WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00033065:clk-1(qm30)_upregulated
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:bodywall-muscle_embryo_enriched
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:coelomocytes_L2-larva_expressed
      WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
      WBPaper00037950:hypodermis_embryo_enriched
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
      WBPaper00041370:spg-7(RNAi)_upregulated_atfs-1_dependent
      WBPaper00045774:clk-1_upregulated
      WBPaper00048971:daf-16(mgDf50)_downregulated_L1
      WBPaper00050448:KGB-1-induced
      WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
      WBPaper00050488:20C_vs_25C_regulated_mir-34(OverExpression)_adult
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:daf-2(e1370)_vs_daf-2(e1370);mir-34(gk437)_regulated_dauer_25C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:mir-34(OverExpression)_vs_N2_regulated_adult_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_adult_25C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053308:SMG-2_associated_NMD(-)_upregulated_ClassI
      WBPaper00053810:clk-1(qm30)_downregulated
      WBPaper00053810:daf-2(e1370)_downregulated
      WBPaper00053810:isp-1(qm150)_downregulated
      WBPaper00053810:nuo-6(qm200)_downregulated
      WBPaper00053810:sod-2(ok1030)_downregulated
      WBPaper00053909:N2_vs_CB4856_downregulated
      WBPaper00055941:nuo-6(qm200)_downregulated
      WBPaper00060014:set-2(tm1630)_upregulated
      WBPaper00061527:F54D5.3_7003-F54D5.3_7004
      WBPaper00062325:muscle_depleted_noncoding-RNA
      WBPaper00065841:20_2
      cgc4489_group_11
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00027342:alpha-Synuclein(WT)_upregulated
      WBPaper00030985:Enterococcus_faecalis_downregulated
      WBPaper00031003:0hr_muscle_depleted
      WBPaper00031003:24hr_muscle_depleted
      WBPaper00031003:total_muscle_depleted
      WBPaper00034757:up_by_oxidative_stress
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00036286:Pattern_I
      WBPaper00037695:LD_3-day
      WBPaper00038427:lin-54_embryo_changed
      WBPaper00040184:hcf-1nc_sir-2.1nc_daf-2up
      WBPaper00040858:eQTL_age_regulated_developing
      WBPaper00040963:TA100_up
      WBPaper00040963:TA300_up
      WBPaper00041002:HF_3d_0.2mM_Up
      WBPaper00041002:HF_3d_2.0mM_Up
      WBPaper00041002:HF_11d_2.0mM_Down
      WBPaper00041370:spg-7(RNAi)_upregulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_3h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00042274:tbx-2(bx59)_upregulated
      WBPaper00045960:L1-L4-lethargus_upregulated
      WBPaper00045960:L4-lethargus_upregulated
      WBPaper00048989:N2_rapamycin_upregulated
      WBPaper00053236:Starvation_regulated_N2
    Interaction (19)
  Map_info: Map: V Position: 0.742373 Error: 0.002171
    Positive: Positive_clone: C03G6 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4701
    Pseudo_map_position
  Reference: WBPaper00006476
    WBPaper00026792
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene