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WormBase Tree Display for Gene: WBGene00004920

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Name Class

WBGene00004920EvidencePaper_evidenceWBPaper00005457
SMapS_parentSequenceY71F9B
IdentityVersion1
NameCGC_namesnr-7Person_evidenceWBPerson167
Sequence_nameY71F9B.4
Molecular_nameY71F9B.4
Y71F9B.4.1
CE22871
Other_name1D295Accession_evidenceEMBLAF303264
CELE_Y71F9B.4Accession_evidenceNDBBX284601
Public_namesnr-7
DB_infoDatabaseAceViewgene1D295
WormQTLgeneWBGene00004920
WormFluxgeneWBGene00004920
NDBlocus_tagCELE_Y71F9B.4
PanthergeneCAEEL|WormBase=WBGene00004920|UniProtKB=Q9N4G9
familyPTHR10553
NCBIgene171834
RefSeqproteinNM_058631.8
SwissProtUniProtAccQ9N4G9
TREEFAMTREEFAM_IDTF315099
UniProt_GCRPUniProtAccQ9N4G9
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:36WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classsnr
Allele (14)
StrainWBStrain00051423
RNASeq_FPKM (74)
GO_annotation (25)
Contained_in_operonCEOP1056
Ortholog (37)
ParalogWBGene00003081Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionsnr-7 encodes the C. elegans ortholog of the small nuclear ribonucleoprotein G, one of seven subunits of the heptameric Sm complex required for the biogenesis and function of snRNPs that catalyze mRNA splicing; in addition to its predicted role in pre-mRNA processing, SNR-7 activity is essential for embryogenesis and for several aspects of germ cell specification including localization and subcellular distribution of P granules and maintenance of transcriptional quiescence; snr-7 is also required for RNA interference and for the overall health and fertility of the animal; immunostaining of adults and embryos using antibodies raised against mammalian Sm proteins and mammalian SmG, in particular, suggests that SNR-7 localizes to the nucleus and cytoplasm in many cell types, as well as to P granules in germ cells and their embryonic precursors.Paper_evidenceWBPaper00004402
WBPaper00005457
WBPaper00006395
WBPaper00024497
WBPaper00025054
WBPaper00026593
WBPaper00027038
Curator_confirmedWBPerson1843
Date_last_updated25 Jul 2006 00:00:00
Automated_descriptionPredicted to contribute to RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Located in P granule. Expressed in gonad. Human ortholog(s) of this gene implicated in nasopharynx carcinoma. Is an ortholog of human SNRPG (small nuclear ribonucleoprotein polypeptide G).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:9261Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11163)
Molecular_infoCorresponding_CDSY71F9B.4
Corresponding_transcriptY71F9B.4.1
Other_sequence (105)
Associated_featureWBsf643102
WBsf656078
WBsf982962
WBsf1009394
WBsf217333
WBsf217334
Experimental_infoRNAi_result (22)
Expr_patternExpr2229
Expr1011571
Expr1032449
Expr1161600
Expr2015971
Expr2034206
AntibodyWBAntibody00000550
WBAntibody00000552
WBAntibody00000553
WBAntibody00000555
Microarray_results (21)
Expression_cluster (131)
Interaction (164)
Map_infoMapIPosition-7.2981Error0.006142
PositivePositive_cloneY71F9BInferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00005457
WBPaper00026593
WBPaper00027038
WBPaper00038491
WBPaper00040897
WBPaper00046572
WBPaper00049828
WBPaper00055090
WBPaper00064339
WBPaper00065026
RemarkLocus was previously incorrectly associated with ZK652.1 [030219 krb]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene