WormBase Tree Display for Gene: WBGene00004807

WBGene00004807 Evidence: CGC_data_submission
  SMap: S_parent: Sequence: CHROMOSOME_I
  Identity: Version: 1
    Name: CGC_name: skr-1 Person_evidence: WBPerson322
      Sequence_name: F46A9.5
      Molecular_name: F46A9.5
        F46A9.5.1
        CE10580
      Other_name: CELE_F46A9.5 Accession_evidence: NDB BX284601
      Public_name: skr-1
    DB_info: Database: AceView gene 1K49
        WormQTL gene WBGene00004807
        WormFlux gene WBGene00004807
        NDB locus_tag CELE_F46A9.5
        Panther gene CAEEL|WormBase=WBGene00004807|UniProtKB=G5ECU1
          family PTHR11165
        NCBI gene 172775
        RefSeq protein NM_060112.8
        SwissProt UniProtAcc G5ECU1
        TREEFAM TREEFAM_ID TF354233
        UniProt_GCRP UniProtAcc G5ECU1
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:36 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: skr
    Allele (14)
    Strain: WBStrain00036440
      WBStrain00005195
    RNASeq_FPKM (74)
    GO_annotation (32)
    Ortholog (44)
    Paralog (19)
    Structured_description: Concise_description: The skr-1 gene encodes a homolog of Skp1 in S. cerevisiae that is required for the restraint of cell proliferation, progression through the pachytene stage of meiosis, and the formation of bivalent chromosomes at diakinesis. Paper_evidence: WBPaper00005128
            WBPaper00005129
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable cullin family protein binding activity. Involved in several processes, including negative regulation of intracellular signal transduction; regulation of cellular component organization; and regulation of protein stability. Predicted to be located in cytoplasm and nucleus. Expressed in several structures, including pharynx and spermatheca. Is an ortholog of human SKP1 (S-phase kinase associated protein 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F46A9.5
    Corresponding_transcript: F46A9.5.1
    Other_sequence (144)
    Associated_feature: WBsf643588
      WBsf643589
      WBsf656751
      WBsf656752
      WBsf984704
      WBsf218286
      WBsf218287
      WBsf218288
      WBsf218289
  Experimental_info: RNAi_result (53)
    Expr_pattern: Expr2437
      Expr13172
      Expr1013389
      Expr1032386
      Expr1151310
      Expr2015847
      Expr2034080
    Drives_construct: WBCnstr00010827
      WBCnstr00035375
    Construct_product: WBCnstr00010827
      WBCnstr00035375
      WBCnstr00039337
    Regulate_expr_cluster: WBPaper00050332:skr-1(RNAi)-skr-2(RNAi)_downregulated
    Antibody: WBAntibody00002336
      WBAntibody00002337
    Microarray_results (24)
    Expression_cluster: WBPaper00032528:L3_enriched
      WBPaper00037950:dopaminergic-neurons_larva_enriched
      WBPaper00038118:stress_upregulated_N2
      WBPaper00038289:oocyte_protein
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
      WBPaper00045521:Gender_Neutral
      WBPaper00045974:NSM_enriched_DSN-treated_RNAseq
      WBPaper00045974:NSM_enriched_totalRNA_RNAseq
      WBPaper00048988:neuron_expressed
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated
      WBPaper00050332:skr-1(RNAi)-skr-2(RNAi)_downregulated
      WBPaper00050344:AFD-neuron_enriched
      WBPaper00050344:PLM-neuron_enriched
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00050990:seam_expressed
      WBPaper00051039:germline_enriched
      WBPaper00051245:body-wall-muscle_cytoplasm_expressed
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:epidermis_nucleus_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051245:intestine_nucleus_expressed
      WBPaper00051245:pharyngeal-muscle_cytoplasm_expressed
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053321:embryo-to-L1_downregulated_nos-1(gv5)nos-2(RNAi)_SMARTseq
      WBPaper00053321:PGCs_depleted_NuGen
      WBPaper00053388:dauer_regulated_Cluster2
      WBPaper00053810:daf-2(e1370)_upregulated
      WBPaper00055049:S.gordonii_upregulated
      WBPaper00055565:AVK_enriched
      WBPaper00055626:pry-1(mu38)_downregulated
      WBPaper00055648:germline_expressed
      WBPaper00056139:soil-microbiota_upregulated
      WBPaper00059356:BAZ-2_SET-6_interacting
      WBPaper00059471:EGL-43_interacting
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060811:L1_vs_adult_upregulated_neural
      WBPaper00061377:MYRF-1_interacting
      WBPaper00061527:unc-44_403-H24G06.1_2859
      WBPaper00061651:HSN_enriched
      WBPaper00061651:I4_enriched
      WBPaper00061651:MC_enriched
      WBPaper00061651:PVP_enriched
      WBPaper00061651:PVW_enriched
      WBPaper00061651:VA12_enriched
      WBPaper00061651:VB01_enriched
      WBPaper00061651:VC_enriched
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00062498:PPM-1.D_interacting
      WBPaper00062554:MAGU-2_interacting
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00063976:micu-1(bon20)_downregulated
      WBPaper00064055:trl-1(cas1077)_downregulated_non-starved
      WBPaper00064055:trl-1(cas1077)_downregulated_starved
      WBPaper00064071:NHR-49_interacting
      WBPaper00064315:mrg-1(qa6200)_downregulated_PGCs
      WBPaper00064871:hypoxia_downregulated_F1
      WBPaper00064992:Eugenol_upregulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00066085:sin-3(syb2172)_downregulated
      cgc4386_cluster_6_3
      cgc4489_group_12
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:Resveratrol_regulated_daf-16
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00030839:Embryo_Pan_Neuronal
      WBPaper00030985:Erwinia_carotovora_upregulated
      WBPaper00030985:Photorhabdus_luminescens_upregulated
      WBPaper00032165:differentially_expressed_with_age_medoid_1
      WBPaper00034739:N2moreDR1350
      WBPaper00035560:ahr-1_downregulated
      WBPaper00035905:FBF-1_Associated
      WBPaper00036123:Atrazine_regulated
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00042331:a-SWCNTs_downregulated
      WBPaper00045263:nuo-6(qm200)_downregulated
      WBPaper00048624:hlh-25(ok1710)_upregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_downregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_SM
    Interaction (235)
    WBProcess: WBbiopr:00000068
  Map_info: Map: I Position: 3.76789 Error: 0.000506
    Positive: Positive_clone: F46A9 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (31)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene