WormBase Tree Display for Gene: WBGene00004795
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| WBGene00004795 | SMap | S_parent | Sequence | C04F5 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | sid-1 | Person_evidence | WBPerson278 | |||||
| Sequence_name | C04F5.1 | ||||||||
| Molecular_name | C04F5.1 | ||||||||
| C04F5.1.1 | |||||||||
| CE30331 | |||||||||
| Other_name | rsd-8 | Person_evidence | WBPerson1521 | ||||||
| WBPerson1463 | |||||||||
| WBPerson2581 | |||||||||
| Author_evidence | Plasterk RHA | ||||||||
| rde-7 | Paper_evidence | WBPaper00036036 | |||||||
| CELE_C04F5.1 | Accession_evidence | NDB | BX284605 | ||||||
| Public_name | sid-1 | ||||||||
| DB_info | Database | AceView | gene | 5F603 | |||||
| WormQTL | gene | WBGene00004795 | |||||||
| WormFlux | gene | WBGene00004795 | |||||||
| NDB | locus_tag | CELE_C04F5.1 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00004795|UniProtKB=Q9GZC8 | |||||||
| family | PTHR12185 | ||||||||
| NCBI | gene | 178900 | |||||||
| RefSeq | protein | NM_071971.10 | |||||||
| SwissProt | UniProtAcc | Q9GZC8 | |||||||
| TREEFAM | TREEFAM_ID | TF313076 | |||||||
| UniProt_GCRP | UniProtAcc | Q9GZC8 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:36 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 16 Oct 2013 10:10:50 | WBPerson2970 | Name_change | Other_name | rde-7 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | sid | ||||||||
| Allele (206) | |||||||||
| Strain (13) | |||||||||
| In_cluster | conserved_miRNA_siRNA_cluster | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (23) | |||||||||
| Ortholog (24) | |||||||||
| Paralog | WBGene00012573 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Panther | |||||||||
| WBGene00006477 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00015583 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00018205 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00016253 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | sid-1 encodes a dsRNA channel with conserved human (OMIM:606816) and mouse homologs; SID-1 functions to enable passive (ATP-independent) uptake of double-stranded RNA (dsRNA) and is required cell autonomously for systemic RNA interference (RNAi) and for efficient reduction of multicopy transgene expression (repeat-induced silencing); SID-1 is not, however, required for export of RNA silencing from C. elegans tissues; a SID-1::GFP fusion is enriched at cellular membranes of most nonneuronal cells from late embryogenesis through adulthood with highest levels detected in cells exposed to the environment; SID-1 extracellular domain (ECD) selectively binds long double-stranded RNA (dsRNA) and the binding affinity is related to RNA transport efficiency. | Paper_evidence | WBPaper00005171 | |||||
| WBPaper00006046 | |||||||||
| WBPaper00032513 | |||||||||
| WBPaper00046955 | |||||||||
| Person_evidence | WBPerson30282 | ||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson324 | |||||||||
| Date_last_updated | 09 Dec 2015 00:00:00 | ||||||||
| Automated_description | Enables RNA transmembrane transporter activity and double-stranded RNA binding activity. Involved in dsRNA transport and regulatory ncRNA-mediated post-transcriptional gene silencing. Located in plasma membrane. Expressed in several structures, including pharynx. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | C04F5.1 | |||||||
| Corresponding_transcript | C04F5.1.1 | ||||||||
| Other_sequence | CRC01416_1 | ||||||||
| Tcol_isotig15794 | |||||||||
| CJC06957_1 | |||||||||
| MAC02131_1 | |||||||||
| Associated_feature | WBsf1019590 | ||||||||
| WBsf231727 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00076077 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00039639 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00085060 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00000928 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00010132 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1867 | ||||||||
| Expr11213 | |||||||||
| Expr13321 | |||||||||
| Expr1023218 | |||||||||
| Expr1032379 | |||||||||
| Expr1143735 | |||||||||
| Expr2015814 | |||||||||
| Expr2034047 | |||||||||
| Drives_construct | WBCnstr00010496 | ||||||||
| WBCnstr00018224 | |||||||||
| WBCnstr00035384 | |||||||||
| Construct_product (21) | |||||||||
| Regulate_expr_cluster | WBPaper00064375:sid-1(pk3321)_regulated | ||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (131) | |||||||||
| Interaction (29) | |||||||||
| Anatomy_function | WBbtf0731 | ||||||||
| Map_info | Map | V | Position | -2.49497 | Error | 0.00506 | |||
| Positive | Positive_clone | C04F5 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 5629 | |||||||
| Pseudo_map_position | |||||||||
| Reference (114) | |||||||||
| Remark | Sequence connection from [Winston W, Hunter C] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
