WormBase Tree Display for Gene: WBGene00004721
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| WBGene00004721 | Evidence | Paper_evidence | WBPaper00006169 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Person_evidence | WBPerson537 | ||||||||
| SMap | S_parent | Sequence | ZC328 | ||||||
| Identity | Version | 3 | |||||||
| Name | CGC_name | san-1 | Paper_evidence | WBPaper00028738 | |||||
| Person_evidence | WBPerson84 | ||||||||
| WBPerson205 | |||||||||
| Sequence_name | ZC328.4 | ||||||||
| Molecular_name | ZC328.4 | ||||||||
| ZC328.4.1 | |||||||||
| CE34445 | |||||||||
| Other_name | mdf-3 | Person_evidence | WBPerson205 | ||||||
| mad-3 | Person_evidence | WBPerson1836 | |||||||
| CELE_ZC328.4 | Accession_evidence | NDB | BX284601 | ||||||
| Public_name | san-1 | ||||||||
| DB_info | Database | AceView | gene | 1G985 | |||||
| WormQTL | gene | WBGene00004721 | |||||||
| WormFlux | gene | WBGene00004721 | |||||||
| NDB | locus_tag | CELE_ZC328.4 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00004721|UniProtKB=O02053 | |||||||
| family | PTHR14030 | ||||||||
| NCBI | gene | 172342 | |||||||
| RefSeq | protein | NM_059445.7 | |||||||
| TREEFAM | TREEFAM_ID | TF344222 | |||||||
| TrEMBL | UniProtAcc | O02053 | |||||||
| UniProt_GCRP | UniProtAcc | O02053 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:36 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 23 Feb 2007 15:37:00 | WBPerson2970 | Name_change | CGC_name | san-1 | ||||
| Other_name | mdf-3 | ||||||||
| 3 | 19 Nov 2013 09:52:28 | WBPerson2970 | Name_change | Other_name | mad-3 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | san | ||||||||
| Allele (17) | |||||||||
| Strain | WBStrain00032089 | ||||||||
| WBStrain00000067 | |||||||||
| WBStrain00034701 | |||||||||
| WBStrain00054972 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (15) | |||||||||
| Ortholog (27) | |||||||||
| Paralog | WBGene00000275 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | san-1 encodes the C. elegans ortholog of the Saccharomyces cerevisiae spindle checkpoint protein Mad3p; san-1 is essential for the mitotic spindle checkpoint activity in response to stimuli such as microtubule depolymerization or anoxia, in which microscopically visible movement ceases and cell cycle progression reversibly arrests; san-1 has also been reported to be essential for normal embryonic development; SAN-1 localizes to the nucleus during prophase and, during metaphase, colocalizes with HCP-3 to the kinetochore, consistent with a role as a spindle checkpoint component. | Paper_evidence | WBPaper00006169 | |||||
| WBPaper00024925 | |||||||||
| WBPaper00026995 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 17 Dec 2007 00:00:00 | ||||||||
| Automated_description | Predicted to enable protein kinase activity. Involved in mitotic spindle assembly checkpoint signaling and response to anoxia. Located in kinetochore and nucleoplasm. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | ZC328.4 | |||||||
| Corresponding_CDS_history | ZC328.4:wp102 | ||||||||
| Corresponding_transcript | ZC328.4.1 | ||||||||
| Other_sequence (18) | |||||||||
| Associated_feature | WBsf643365 | ||||||||
| WBsf643366 | |||||||||
| WBsf217820 | |||||||||
| Experimental_info | RNAi_result (21) | ||||||||
| Expr_pattern | Expr2761 | ||||||||
| Expr1022181 | |||||||||
| Expr1032328 | |||||||||
| Expr1162277 | |||||||||
| Expr2015591 | |||||||||
| Expr2033826 | |||||||||
| Drives_construct | WBCnstr00035429 | ||||||||
| Construct_product | WBCnstr00005579 | ||||||||
| WBCnstr00035429 | |||||||||
| Antibody | WBAntibody00000691 | ||||||||
| Microarray_results (24) | |||||||||
| Expression_cluster (144) | |||||||||
| Interaction (137) | |||||||||
| Map_info | Map | I | Position | 1.07223 | Error | 0.001571 | |||
| Positive | Positive_clone | ZC328 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 5246 | |||||||
| 4681 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (28) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| This gene has been named mad (Mitotic Arrest Deficient) in other species and so mad-3 has been added as an other_name | |||||||||
| Method | Gene |
