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WormBase Tree Display for Gene: WBGene00004359

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Name Class

WBGene00004359SMapS_parentSequenceB0240
IdentityVersion1
NameCGC_namerhr-2
Sequence_nameB0240.1
Molecular_nameB0240.1
B0240.1.1
CE05172
Other_nameCELE_B0240.1Accession_evidenceNDBBX284605
Public_namerhr-2
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:35WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classrhr
AlleleWBVar01499904
WBVar01499905
WBVar01499547
WBVar01974877
WBVar01499190
WBVar00091698
WBVar01866237
WBVar01866238
WBVar01866239
WBVar01461859
WBVar00005380
WBVar01050586
WBVar01050587
WBVar01050588
WBVar01050589
WBVar01050590
WBVar01050591
WBVar01050592
WBVar01050593
WBVar01500208
WBVar01500209
WBVar01050594
WBVar01050595
WBVar01050596
WBVar01500212
WBVar01050597
WBVar01500213
WBVar01499299
WBVar00471323
WBVar00471324
WBVar00471325
WBVar00471326
WBVar00471327
WBVar01499316
Legacy_information[Nettell J] rhr for Rh blood group antigen related. No mutants known. Predicted gene B0240.1
StrainWBStrain00030767
WBStrain00031392
RNASeq_FPKM (74)
GO_annotation (12)
Ortholog (42)
ParalogWBGene00000133Caenorhabditis elegansFrom_analysisPanther
WBGene00000134Caenorhabditis elegansFrom_analysisPanther
WBGene00000135Caenorhabditis elegansFrom_analysisPanther
WBGene00000136Caenorhabditis elegansFrom_analysisPanther
WBGene00004358Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionrhr-2 encodes a predicted transmembrane protein with similarity to human Rh blood group antigens proposed to function in inorganic ion transport and metabolism; the role of RHR-2 in C. elegans development or behavior remains unclear, as loss of RHR-2 function via RNA-mediated interference does not result in any abnormalities.Paper_evidenceWBPaper00005654
Curator_confirmedWBPerson1843
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable ammonium transmembrane transporter activity. Predicted to be involved in ammonium homeostasis and ammonium transmembrane transport. Located in apical plasma membrane. Expressed in several structures, including body wall musculature; head neurons; spermatheca; ventral nerve cord; and vulva. Human ortholog(s) of this gene implicated in Rh deficiency syndrome and overhydrated hereditary stomatocytosis. Is an ortholog of human RHAG (Rh associated glycoprotein); RHBG (Rh family B glycoprotein); and RHCG (Rh family C glycoprotein).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0050641Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10006)
DOID:0111562Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10006)
DOID:583Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:10006)
Molecular_infoCorresponding_CDSB0240.1
Corresponding_transcriptB0240.1.1
Other_sequence (21)
Associated_featureWBsf234571
WBsf234572
Experimental_infoRNAi_resultWBRNAi00009624Inferred_automaticallyRNAi_primary
WBRNAi00038784Inferred_automaticallyRNAi_primary
WBRNAi00028024Inferred_automaticallyRNAi_primary
WBRNAi00077595Inferred_automaticallyRNAi_primary
Expr_patternExpr3970
Expr12741
Expr1027846
Expr1142991
Expr2015340
Expr2033574
Drives_constructWBCnstr00035540
Construct_productWBCnstr00022779
WBCnstr00035540
Microarray_results (18)
Expression_cluster (90)
InteractionWBInteraction000328271
WBInteraction000389534
WBInteraction000390827
WBInteraction000439732
Map_infoMapVPosition3.30848Error0.00541
PositivePositive_cloneB0240Author_evidenceNettell JJ
Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point4636
4844
4808
5619
Pseudo_map_position
ReferenceWBPaper00019491
WBPaper00027209
WBPaper00032929
WBPaper00038491
WBPaper00046515
WBPaper00049246
WBPaper00055090
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene