WormBase Tree Display for Gene: WBGene00004303

WBGene00004303 SMap: S_parent: Sequence: C29E4
  Identity: Version: 2
    Name: CGC_name: ran-2
      Sequence_name: C29E4.3
      Molecular_name: C29E4.3a
        C29E4.3a.1
        CE37483
        C29E4.3b
        CE30621
        C29E4.3b.1
        C29E4.3b.2
      Other_name: pna-3 Person_evidence: WBPerson561
        CELE_C29E4.3 Accession_evidence: NDB BX284603
      Public_name: ran-2
    DB_info: Database: AceView gene 3J25
        WormQTL gene WBGene00004303
        WormFlux gene WBGene00004303
        NDB locus_tag CELE_C29E4.3
        Panther gene CAEEL|WormBase=WBGene00004303|UniProtKB=P34342
          family PTHR24113
        NCBI gene 176115
        RefSeq protein NM_171884.5
            NM_171198.8
        SwissProt UniProtAcc P34342
        TREEFAM TREEFAM_ID TF318283
        UniProt_GCRP UniProtAcc P34342
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:34 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 06 Jul 2015 11:34:19 WBPerson2970 Event: Acquires_merge: WBGene00004067
              Name_change: Other_name: pna-3
      Acquires_merge: WBGene00004067
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: ran
    Allele (51)
    Legacy_information: [Schnabel H] maternal effect embryonic lethal with abnormal pronuclear apppearance
    Strain: WBStrain00036599
      WBStrain00007779
      WBStrain00054780
    RNASeq_FPKM (74)
    GO_annotation (13)
    Contained_in_operon: CEOP3465
    Ortholog: WBGene00064113 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00033254 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00159276 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00129815 Caenorhabditis japonica From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00148834 Caenorhabditis brenneri From_analysis: TreeFam
            WormBase-Compara
      WBGene00142899 Caenorhabditis brenneri From_analysis: TreeFam
            WormBase-Compara
      WBGene00142808 Caenorhabditis brenneri From_analysis: TreeFam
            WormBase-Compara
      WBGene00222725 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g5277 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g2510 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g8029 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g5334 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP28.g5337 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g1312 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g11053 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g2511 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g4685 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g4963 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g1047 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      CSP40.g1048 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00638.g13030 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-ran-2 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold629.g12587 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_01701.g22617 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_07979 Caenorhabditis latens From_analysis: WormBase-Compara
      FL83_12085 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_009164 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g03832 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g10023 Panagrellus redivivus From_analysis: WormBase-Compara
      Pan_g10024 Panagrellus redivivus From_analysis: WormBase-Compara
      Pan_g18022 Panagrellus redivivus From_analysis: WormBase-Compara
      Pan_g3073 Panagrellus redivivus From_analysis: WormBase-Compara
      Pan_g3135 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_30045700 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrIII_pilon.g8259 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00245437 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00107495 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00261396 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00290386 Trichuris muris From_analysis: WormBase-Compara
      WBGene00299908 Trichuris muris From_analysis: WormBase-Compara
      SGD:S000004848 Saccharomyces cerevisiae From_analysis: EnsEMBL-Compara
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      FB:FBgn0003346 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-040426-1921 Danio rerio From_analysis: EnsEMBL-Compara
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-060929-492 Danio rerio From_analysis: EnsEMBL-Compara
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      HGNC:9854 Homo sapiens From_analysis: EnsEMBL-Compara
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:103071 Mus musculus From_analysis: EnsEMBL-Compara
            OrthoFinder
            OrthoInspector
            Panther
            SonicParanoid
      RGD:1310380 Rattus norvegicus From_analysis: EnsEMBL-Compara
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
    Structured_description: Concise_description: ran-2 encodes the C. elegans RanGAP (GTPase activating protein) homolog, conserved amongst yeast, Drosophila (segregation distorter), Xenopus, and humans; by homology, RAN-2 is predicted to function as a key regulator of the Ran GTP/GDP cycle by stimulating the otherwise weak Ran GTPase activity; in C. elegans, RAN-2 activity is essential during early embryogenesis for comigration of centrosomes with the male pronucleus, mitotic spindle formation, chromosome segregation, and nuclear envelope assembly; in addition, RAN-2 is also required for nucleocytoplasmic transport; ran-2 reporter gene expression is detected in embryos and larvae. Paper_evidence: WBPaper00004403
            WBPaper00004651
            WBPaper00005178
            WBPaper00005637
            WBPaper00011686
          Curator_confirmed: WBPerson1843
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable GTPase activator activity and small GTPase binding activity. Involved in embryo development. Predicted to be located in cytosol; nucleus; and perinuclear region of cytoplasm. Expressed in intestinal cell. Is an ortholog of human RANGAP1 (Ran GTPase activating protein 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: C29E4.3a
      C29E4.3b
    Corresponding_CDS_history: C29E4.3a:wp130
    Corresponding_transcript: C29E4.3a.1
      C29E4.3b.1
      C29E4.3b.2
    Other_sequence (24)
    Associated_feature: WBsf645370
      WBsf645371
      WBsf976236
      WBsf976237
      WBsf225302
      WBsf225303
      WBsf225304
      WBsf225305
  Experimental_info: RNAi_result: WBRNAi00085739 Inferred_automatically: RNAi_primary
      WBRNAi00062934 Inferred_automatically: RNAi_primary
      WBRNAi00062949 Inferred_automatically: RNAi_primary
      WBRNAi00001007 Inferred_automatically: RNAi_primary
      WBRNAi00041448 Inferred_automatically: RNAi_primary
      WBRNAi00086891 Inferred_automatically: RNAi_primary
      WBRNAi00062955 Inferred_automatically: RNAi_primary
      WBRNAi00002456 Inferred_automatically: RNAi_primary
      WBRNAi00062942 Inferred_automatically: RNAi_primary
      WBRNAi00065354 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr2038
      Expr1026981
      Expr1032128
      Expr1145479
      Expr2015251
      Expr2033485
    Microarray_results (20)
    Expression_cluster (122)
    Interaction (111)
  Map_info: Map: III Position: -0.48356 Error: 0.002198
    Positive: Positive_clone: C29E4 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (11)
  Remark: Sequence connection from [Askjaer P, Mattaj IW]. krb 13/11/01
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene