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WormBase Tree Display for Gene: WBGene00004303

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Name Class

WBGene00004303SMapS_parentSequenceC29E4
IdentityVersion2
NameCGC_nameran-2
Sequence_nameC29E4.3
Molecular_nameC29E4.3a
C29E4.3a.1
CE37483
C29E4.3b
CE30621
C29E4.3b.1
C29E4.3b.2
Other_namepna-3Person_evidenceWBPerson561
CELE_C29E4.3Accession_evidenceNDBBX284603
Public_nameran-2
DB_infoDatabaseAceViewgene3J25
WormQTLgeneWBGene00004303
WormFluxgeneWBGene00004303
NDBlocus_tagCELE_C29E4.3
PanthergeneCAEEL|WormBase=WBGene00004303|UniProtKB=P34342
familyPTHR24113
NCBIgene176115
RefSeqproteinNM_171884.5
NM_171198.8
SwissProtUniProtAccP34342
TREEFAMTREEFAM_IDTF318283
UniProt_GCRPUniProtAccP34342
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:34WBPerson1971EventImportedInitial conversion from geneace
206 Jul 2015 11:34:19WBPerson2970EventAcquires_mergeWBGene00004067
Name_changeOther_namepna-3
Acquires_mergeWBGene00004067
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classran
Allele (51)
Legacy_information[Schnabel H] maternal effect embryonic lethal with abnormal pronuclear apppearance
StrainWBStrain00036599
WBStrain00007779
WBStrain00054780
RNASeq_FPKM (74)
GO_annotation (13)
Contained_in_operonCEOP3465
Ortholog (47)
Structured_descriptionConcise_descriptionran-2 encodes the C. elegans RanGAP (GTPase activating protein) homolog, conserved amongst yeast, Drosophila (segregation distorter), Xenopus, and humans; by homology, RAN-2 is predicted to function as a key regulator of the Ran GTP/GDP cycle by stimulating the otherwise weak Ran GTPase activity; in C. elegans, RAN-2 activity is essential during early embryogenesis for comigration of centrosomes with the male pronucleus, mitotic spindle formation, chromosome segregation, and nuclear envelope assembly; in addition, RAN-2 is also required for nucleocytoplasmic transport; ran-2 reporter gene expression is detected in embryos and larvae.Paper_evidenceWBPaper00004403
WBPaper00004651
WBPaper00005178
WBPaper00005637
WBPaper00011686
Curator_confirmedWBPerson1843
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable GTPase activator activity and small GTPase binding activity. Involved in embryo development. Predicted to be located in cytosol; nucleus; and perinuclear region of cytoplasm. Expressed in intestinal cell. Is an ortholog of human RANGAP1 (Ran GTPase activating protein 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSC29E4.3a
C29E4.3b
Corresponding_CDS_historyC29E4.3a:wp130
Corresponding_transcriptC29E4.3a.1
C29E4.3b.1
C29E4.3b.2
Other_sequence (24)
Associated_featureWBsf645370
WBsf645371
WBsf976236
WBsf976237
WBsf225302
WBsf225303
WBsf225304
WBsf225305
Experimental_infoRNAi_resultWBRNAi00085739Inferred_automaticallyRNAi_primary
WBRNAi00062934Inferred_automaticallyRNAi_primary
WBRNAi00062949Inferred_automaticallyRNAi_primary
WBRNAi00001007Inferred_automaticallyRNAi_primary
WBRNAi00041448Inferred_automaticallyRNAi_primary
WBRNAi00086891Inferred_automaticallyRNAi_primary
WBRNAi00062955Inferred_automaticallyRNAi_primary
WBRNAi00002456Inferred_automaticallyRNAi_primary
WBRNAi00062942Inferred_automaticallyRNAi_primary
WBRNAi00065354Inferred_automaticallyRNAi_primary
Expr_patternExpr2038
Expr1026981
Expr1032128
Expr1145479
Expr2015251
Expr2033485
Microarray_results (20)
Expression_cluster (122)
InteractionWBInteraction000009617
WBInteraction000029181
WBInteraction000034441
WBInteraction000035719
WBInteraction000037347
WBInteraction000039902
WBInteraction000040103
WBInteraction000042500
WBInteraction000043791
WBInteraction000045211
WBInteraction000046416
WBInteraction000046771
WBInteraction000047455
WBInteraction000047856
WBInteraction000048112
WBInteraction000048113
WBInteraction000048968
WBInteraction000109062
WBInteraction000112480
WBInteraction000113412
WBInteraction000133039
WBInteraction000133040
WBInteraction000133041
WBInteraction000135952
WBInteraction000137602
WBInteraction000138467
WBInteraction000140711
WBInteraction000141877
WBInteraction000143390
WBInteraction000143867
WBInteraction000144938
WBInteraction000149365
WBInteraction000151564
WBInteraction000159965
WBInteraction000160282
WBInteraction000162031
WBInteraction000163808
WBInteraction000172369
WBInteraction000184431
WBInteraction000198795
WBInteraction000209970
WBInteraction000215290
WBInteraction000221256
WBInteraction000223918
WBInteraction000224479
WBInteraction000231135
WBInteraction000231136
WBInteraction000231309
WBInteraction000237775
WBInteraction000239994
WBInteraction000255585
WBInteraction000256030
WBInteraction000258314
WBInteraction000282077
WBInteraction000282078
WBInteraction000293766
WBInteraction000305144
WBInteraction000312796
WBInteraction000340824
WBInteraction000340825
WBInteraction000340826
WBInteraction000350416
WBInteraction000357919
WBInteraction000362390
WBInteraction000365250
WBInteraction000365251
WBInteraction000382034
WBInteraction000382035
WBInteraction000382036
WBInteraction000407293
WBInteraction000408364
WBInteraction000413845
WBInteraction000414189
WBInteraction000414190
WBInteraction000414273
WBInteraction000426008
WBInteraction000443619
WBInteraction000456706
WBInteraction000464714
WBInteraction000466153
WBInteraction000468792
WBInteraction000469787
WBInteraction000469938
WBInteraction000470897
WBInteraction000471201
WBInteraction000471368
WBInteraction000472824
WBInteraction000474680
WBInteraction000502604
WBInteraction000523213
WBInteraction000523214
WBInteraction000523215
WBInteraction000541668
WBInteraction000542333
WBInteraction000542334
WBInteraction000542335
WBInteraction000549621
WBInteraction000556495
WBInteraction000557992
WBInteraction000559098
WBInteraction000560978
WBInteraction000564480
WBInteraction000565279
WBInteraction000568915
WBInteraction000570121
WBInteraction000570954
WBInteraction000573996
WBInteraction000574918
WBInteraction000577193
WBInteraction000579452
WBInteraction000583100
Map_infoMapIIIPosition-0.48356Error0.002198
PositivePositive_cloneC29E4Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
Reference (11)
RemarkSequence connection from [Askjaer P, Mattaj IW]. krb 13/11/01
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene