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WormBase Tree Display for Gene: WBGene00004178

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Name Class

WBGene00004178SMapS_parentSequenceD2030
IdentityVersion2
NameCGC_nameprg-1
Sequence_nameD2030.6
Molecular_nameD2030.6
D2030.6.1
CE09083
Other_nameCELE_D2030.6Accession_evidenceNDBBX284601
Public_nameprg-1
DB_infoDatabaseAceViewgene1I162
WormQTLgeneWBGene00004178
WormFluxgeneWBGene00004178
NDBlocus_tagCELE_D2030.6
PanthergeneCAEEL|WormBase=WBGene00004178|UniProtKB=P90786
familyPTHR22891
NCBIgene172515
RefSeqproteinNM_059720.7
TREEFAMTREEFAM_IDTF350431
TrEMBLUniProtAccP90786
UniProt_GCRPUniProtAccP90786
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:34WBPerson1971EventImportedInitial conversion from geneace
205 Nov 2007 17:02:03WBPerson2970EventAcquires_mergeWBGene00008416
Name_changeSequence_nameD2030.6
Acquires_mergeWBGene00008416
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classprg
AlleleWBVar02152943Inferred_automaticallyFrom strain object: CZ25708
WBVar02148889
WBVar02148650
WBVar02150052
WBVar02157862
WBVar02157863
WBVar02157864
WBVar02158379
WBVar00338500
WBVar00338501
WBVar00338502
WBVar00090833
WBVar00249897
WBVar00090849
WBVar00650475
WBVar00650476
WBVar00650477
WBVar00650478
WBVar00650479
WBVar00650480
WBVar00650481
WBVar00650482
WBVar00650483
WBVar00650484
WBVar00650485
WBVar00650486
WBVar00650487
WBVar00650488
WBVar00650489
WBVar00650490
WBVar00650491
WBVar00650492
WBVar00650493
WBVar00650494
WBVar00650495
WBVar00650496
WBVar00650497
WBVar00650498
WBVar00650499
WBVar00650500
WBVar00650501
WBVar00650502
WBVar00650503
WBVar00650504
WBVar00650505
WBVar00650506
WBVar00650507
WBVar01909797
WBVar01909798
WBVar00537530
WBVar01499786
WBVar01499054
WBVar00154405
WBVar00239439
WBVar00338492
WBVar00338493
WBVar00338494
WBVar01498959
WBVar00338495
WBVar00338496
WBVar00338497
WBVar00338498
WBVar00338499
Possibly_affected_byWBVar02158857
Strain (21)
In_clusterconserved_RDE-1_cluster
conserved_miRNA_siRNA_cluster
RNASeq_FPKM (74)
GO_annotation (16)
Ortholog (58)
Paralog (22)
Structured_descriptionConcise_descriptionprg-1 encodes a novel, basic protein that is one of two C. elegans members of the Piwi subfamily of highly conserved Argonaut/Piwi proteins; during development, PRG-1 activity is essential for successful gametogenesis, normal levels of fertility, and accumulation of 21 U-RNAs (piRNAs), small RNAs expressed in the germ line; in addition, PRG-1 appears to act upstream of an siRNA pathway to regulate transposition of the Tc3 DNA transposon; PRG-1 physically interacts with 21 U-RNAs in vivo; PRG-1 localizes to P granules throughout development.Paper_evidenceWBPaper00003335
WBPaper00031903
WBPaper00031961
WBPaper00031962
Curator_confirmedWBPerson1843
Date_last_updated24 Jun 2008 00:00:00
Automated_descriptionEnables 21U-RNA binding activity. Involved in 21U-RNA metabolic process; gamete generation; and positive regulation of mitotic nuclear division. Located in P granule. Expressed in germ line and in male. Is an ortholog of human PIWIL1 (piwi like RNA-mediated gene silencing 1) and PIWIL3 (piwi like RNA-mediated gene silencing 3).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSD2030.6
Corresponding_transcriptD2030.6.1
Other_sequence (23)
Associated_featureWBsf649331
WBsf664462
WBsf976794
WBsf976795
WBsf976796
WBsf219788
Experimental_infoRNAi_resultWBRNAi00007898Inferred_automaticallyRNAi_primary
WBRNAi00091976Inferred_automaticallyRNAi_primary
WBRNAi00116862Inferred_automaticallyRNAi_primary
WBRNAi00091977Inferred_automaticallyRNAi_primary
WBRNAi00003287Inferred_automaticallyRNAi_primary
WBRNAi00043476Inferred_automaticallyRNAi_primary
WBRNAi00115384Inferred_automaticallyRNAi_primary
WBRNAi00030403Inferred_automaticallyRNAi_primary
Expr_pattern (11)
Construct_productWBCnstr00004992
WBCnstr00014705
WBCnstr00014708
WBCnstr00014740
WBCnstr00014829
WBCnstr00016668
Regulate_expr_cluster (24)
AntibodyWBAntibody00001434
WBAntibody00001435
WBAntibody00002378
WBAntibody00002379
WBAntibody00002584
Microarray_results (17)
Expression_cluster (165)
Interaction (1008)
Map_infoMapIPosition2.18374Error0.005084
PositivePositive_cloneD2030Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (101)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene