WormBase Tree Display for Gene: WBGene00004178
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| WBGene00004178 | SMap | S_parent | Sequence | D2030 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | prg-1 | |||||||
| Sequence_name | D2030.6 | ||||||||
| Molecular_name | D2030.6 | ||||||||
| D2030.6.1 | |||||||||
| CE09083 | |||||||||
| Other_name | CELE_D2030.6 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | prg-1 | ||||||||
| DB_info | Database | AceView | gene | 1I162 | |||||
| WormQTL | gene | WBGene00004178 | |||||||
| WormFlux | gene | WBGene00004178 | |||||||
| NDB | locus_tag | CELE_D2030.6 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00004178|UniProtKB=P90786 | |||||||
| family | PTHR22891 | ||||||||
| NCBI | gene | 172515 | |||||||
| RefSeq | protein | NM_059720.7 | |||||||
| TREEFAM | TREEFAM_ID | TF350431 | |||||||
| TrEMBL | UniProtAcc | P90786 | |||||||
| UniProt_GCRP | UniProtAcc | P90786 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:34 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 05 Nov 2007 17:02:03 | WBPerson2970 | Event | Acquires_merge | WBGene00008416 | ||||
| Name_change | Sequence_name | D2030.6 | |||||||
| Acquires_merge | WBGene00008416 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | prg | ||||||||
| Allele (63) | |||||||||
| Possibly_affected_by | WBVar02158857 | ||||||||
| Strain (21) | |||||||||
| In_cluster | conserved_RDE-1_cluster | ||||||||
| conserved_miRNA_siRNA_cluster | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (16) | |||||||||
| Ortholog (58) | |||||||||
| Paralog (22) | |||||||||
| Structured_description | Concise_description | prg-1 encodes a novel, basic protein that is one of two C. elegans members of the Piwi subfamily of highly conserved Argonaut/Piwi proteins; during development, PRG-1 activity is essential for successful gametogenesis, normal levels of fertility, and accumulation of 21 U-RNAs (piRNAs), small RNAs expressed in the germ line; in addition, PRG-1 appears to act upstream of an siRNA pathway to regulate transposition of the Tc3 DNA transposon; PRG-1 physically interacts with 21 U-RNAs in vivo; PRG-1 localizes to P granules throughout development. | Paper_evidence | WBPaper00003335 | |||||
| WBPaper00031903 | |||||||||
| WBPaper00031961 | |||||||||
| WBPaper00031962 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 24 Jun 2008 00:00:00 | ||||||||
| Automated_description | Enables 21U-RNA binding activity. Involved in 21U-RNA metabolic process; gamete generation; and positive regulation of mitotic nuclear division. Located in P granule. Expressed in germ line and in male. Is an ortholog of human PIWIL1 (piwi like RNA-mediated gene silencing 1) and PIWIL3 (piwi like RNA-mediated gene silencing 3). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | D2030.6 | |||||||
| Corresponding_transcript | D2030.6.1 | ||||||||
| Other_sequence (23) | |||||||||
| Associated_feature | WBsf649331 | ||||||||
| WBsf664462 | |||||||||
| WBsf976794 | |||||||||
| WBsf976795 | |||||||||
| WBsf976796 | |||||||||
| WBsf219788 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00007898 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00091976 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00116862 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00091977 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00003287 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00043476 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00115384 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00030403 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern (11) | |||||||||
| Construct_product | WBCnstr00004992 | ||||||||
| WBCnstr00014705 | |||||||||
| WBCnstr00014708 | |||||||||
| WBCnstr00014740 | |||||||||
| WBCnstr00014829 | |||||||||
| WBCnstr00016668 | |||||||||
| Regulate_expr_cluster (24) | |||||||||
| Antibody | WBAntibody00001434 | ||||||||
| WBAntibody00001435 | |||||||||
| WBAntibody00002378 | |||||||||
| WBAntibody00002379 | |||||||||
| WBAntibody00002584 | |||||||||
| Microarray_results (17) | |||||||||
| Expression_cluster (165) | |||||||||
| Interaction (1008) | |||||||||
| Map_info | Map | I | Position | 2.18374 | Error | 0.005084 | |||
| Positive | Positive_clone | D2030 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (101) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
