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WormBase Tree Display for Gene: WBGene00004027

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Name Class

WBGene00004027SMapS_parentSequenceY49E10
IdentityVersion1
NameCGC_namepie-1Person_evidenceWBPerson498
Sequence_nameY49E10.14
Molecular_nameY49E10.14a
Y49E10.14a.1
CE28134
Y49E10.14b
CE45773
Y49E10.14b.1
Other_namepic-1
CELE_Y49E10.14Accession_evidenceNDBBX284603
Public_namepie-1
DB_infoDatabaseAceViewgene3N517
WormQTLgeneWBGene00004027
WormFluxgeneWBGene00004027
NDBlocus_tagCELE_Y49E10.14
PanthergeneCAEEL|WormBase=WBGene00004027|UniProtKB=Q94131
familyPTHR12547
NCBIgene176667
RefSeqproteinNM_001268238.3
NM_001268237.2
SwissProtUniProtAccQ94131
TREEFAMTREEFAM_IDTF318914
UniProt_GCRPUniProtAccQ94131
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:33WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classpie
Allele (78)
Legacy_information[C.elegansII] zu154 : maternal effect lethal, often with two distinct pharynges; additional pharynx and intestinal tissue from P2 (transformed to EMS fate).OA1. Cloned: encodes zinc finger protein, localized to nuclei of germ line blastomeres. [Mello et al. 1992; Mango et al. 1994; EU; JJ]
Strain (76)
RNASeq_FPKM (74)
GO_annotation (33)
Ortholog (26)
Paralog (20)
Structured_descriptionConcise_descriptionpie-1 encodes a C-x8-C-x5-C-x3-H-type zinc-finger protein; maternally provided PIE-1 is essential for germline cell fate determination, as it functions as a repressor of RNA polymerase II-dependent gene expression in the developing germ line; PIE-1 localization, initially uniform and then concentrated in the posterior germ cell lineages, is regulated by other maternally supplied gene products including PAR-1, MEX-5, and MEX-6.Paper_evidenceWBPaper00004304
WBPaper00004631
WBPaper00005297
WBPaper00005347
WBPaper00005605
WBPaper00005735
WBPaper00005791
Curator_confirmedWBPerson1843
Date_last_updated30 Nov 2004 00:00:00
Automated_descriptionPredicted to enable mRNA 3'-UTR binding activity. Involved in several processes, including embryonic pattern specification; formation of primary germ layer; and negative regulation of nitrogen compound metabolic process. Located in several cellular components, including P granule; centrosome; and cytosol. Expressed in germ line; head muscle; and nerve ring.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSY49E10.14a
Y49E10.14b
Corresponding_CDS_historyY49E10.14:wp52
Corresponding_transcriptY49E10.14a.1
Y49E10.14b.1
Other_sequence (3)
Associated_featureWBsf047506
WBsf645660
WBsf659608
WBsf976032
WBsf976033
WBsf976034
WBsf978688
WBsf994644
WBsf225904
Transcription_factorWBTranscriptionFactor000460
Experimental_infoRNAi_result (65)
Expr_pattern (17)
Drives_constructWBCnstr00000071
WBCnstr00000072
WBCnstr00000075
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WBCnstr00039670
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WBCnstr00041068
WBCnstr00041069
WBCnstr00041368
WBCnstr00041655
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WBCnstr00043031
Construct_product (18)
Regulate_expr_clusterWBPaper00061478:pie-1(ne4303)_upregulated
WBPaper00061478:pie-1(ne4433)_upregulated
AntibodyWBAntibody00000118
WBAntibody00000189
WBAntibody00000697
WBAntibody00001076
WBAntibody00001395
WBAntibody00001588
WBAntibody00001589
Microarray_results (24)
Expression_cluster (152)
Interaction (309)
WBProcessWBbiopr:00000017
Map_infoMapIIIPosition17.7453Error0.045821
Well_ordered
PositiveInside_rearrctDf3
Positive_clonepJP604
Y49E10Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point (11)
Pos_neg_data8413
8414
8548
8557
Landmark_gene
Reference (314)
MethodGene