| WBGene00004027 | SMap | S_parent | Sequence | Y49E10 |
|---|
| Identity | Version | 1 |
| | Name | CGC_name | pie-1 | Person_evidence | WBPerson498 |
| | | Sequence_name | Y49E10.14 |
| | | Molecular_name | Y49E10.14a |
| | | | Y49E10.14a.1 |
| | | | CE28134 |
| | | | Y49E10.14b |
| | | | CE45773 |
| | | | Y49E10.14b.1 |
| | | Other_name | pic-1 |
| | | | CELE_Y49E10.14 | Accession_evidence | NDB | BX284603 |
| | | Public_name | pie-1 |
| | DB_info | Database | AceView | gene | 3N517 |
| | | | WormQTL | gene | WBGene00004027 |
| | | | WormFlux | gene | WBGene00004027 |
| | | | NDB | locus_tag | CELE_Y49E10.14 |
| | | | Panther | gene | CAEEL|WormBase=WBGene00004027|UniProtKB=Q94131 |
| | | | | family | PTHR12547 |
| | | | NCBI | gene | 176667 |
| | | | RefSeq | protein | NM_001268238.3 |
| | | | | | NM_001268237.2 |
| | | | SwissProt | UniProtAcc | Q94131 |
| | | | TREEFAM | TREEFAM_ID | TF318914 |
| | | | UniProt_GCRP | UniProtAcc | Q94131 |
| | Species | Caenorhabditis elegans |
| | History | Version_change | 1 | 07 Apr 2004 11:29:33 | WBPerson1971 | Event | Imported | Initial conversion from geneace |
| | Status | Live |
| Gene_info | Biotype | SO:0001217 |
| | Gene_class | pie |
| | Allele (78) |
| | Legacy_information | [C.elegansII] zu154 : maternal effect lethal, often with two distinct pharynges; additional pharynx and intestinal tissue from P2 (transformed to EMS fate).OA1. Cloned: encodes zinc finger protein, localized to nuclei of germ line blastomeres. [Mello et al. 1992; Mango et al. 1994; EU; JJ] |
| | Strain (76) |
| | RNASeq_FPKM (74) |
| | GO_annotation (33) |
| | Ortholog (26) |
| | Paralog (20) |
| | Structured_description | Concise_description | pie-1 encodes a C-x8-C-x5-C-x3-H-type zinc-finger protein; maternally provided PIE-1 is essential for germline cell fate determination, as it functions as a repressor of RNA polymerase II-dependent gene expression in the developing germ line; PIE-1 localization, initially uniform and then concentrated in the posterior germ cell lineages, is regulated by other maternally supplied gene products including PAR-1, MEX-5, and MEX-6. | Paper_evidence | WBPaper00004304 |
| | | | | | WBPaper00004631 |
| | | | | | WBPaper00005297 |
| | | | | | WBPaper00005347 |
| | | | | | WBPaper00005605 |
| | | | | | WBPaper00005735 |
| | | | | | WBPaper00005791 |
| | | | | Curator_confirmed | WBPerson1843 |
| | | | | Date_last_updated | 30 Nov 2004 00:00:00 |
| | | Automated_description | Predicted to enable mRNA 3'-UTR binding activity. Involved in several processes, including embryonic pattern specification; formation of primary germ layer; and negative regulation of nitrogen compound metabolic process. Located in several cellular components, including P granule; centrosome; and cytosol. Expressed in germ line; head muscle; and nerve ring. | Paper_evidence | WBPaper00065943 |
| | | | | Curator_confirmed | WBPerson324 |
| | | | | | WBPerson37462 |
| | | | | Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase |
| | | | | Date_last_updated | 29 Nov 2023 00:00:00 |
| Molecular_info | Corresponding_CDS | Y49E10.14a |
| | | Y49E10.14b |
| | Corresponding_CDS_history | Y49E10.14:wp52 |
| | Corresponding_transcript | Y49E10.14a.1 |
| | | Y49E10.14b.1 |
| | Other_sequence | U62896 |
| | | CBC08706_1 |
| | | CRC03076_1 |
| | Associated_feature | WBsf047506 |
| | | WBsf645660 |
| | | WBsf659608 |
| | | WBsf976032 |
| | | WBsf976033 |
| | | WBsf976034 |
| | | WBsf978688 |
| | | WBsf994644 |
| | | WBsf225904 |
| | Transcription_factor | WBTranscriptionFactor000460 |
| Experimental_info | RNAi_result | WBRNAi00026785 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00103978 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00067109 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00057006 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00101766 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00079052 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00101759 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00103972 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00103976 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00103996 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00082726 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00103982 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00103977 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00082725 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00084333 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00079042 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00103991 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00095794 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00067201 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00103990 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00082724 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00103997 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00087575 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00103980 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00115799 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00103983 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00103995 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00057007 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00103984 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00006812 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00087574 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00103994 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00103988 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00101745 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00007158 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00103973 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00107192 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00103998 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00101758 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00103981 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00009359 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00103993 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00067192 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00103974 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00067132 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00103985 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00101769 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00077659 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00103979 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00084325 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00103986 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00103992 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00082745 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00082723 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00103989 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00082744 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00067572 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00111759 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00106571 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00077644 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00087573 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00084340 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00103987 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00101757 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00103975 | Inferred_automatically | RNAi_primary |
| | Expr_pattern (17) |
| | Drives_construct (720) |
| | Construct_product (18) |
| | Regulate_expr_cluster | WBPaper00061478:pie-1(ne4303)_upregulated |
| | | WBPaper00061478:pie-1(ne4433)_upregulated |
| | Antibody | WBAntibody00000118 |
| | | WBAntibody00000189 |
| | | WBAntibody00000697 |
| | | WBAntibody00001076 |
| | | WBAntibody00001395 |
| | | WBAntibody00001588 |
| | | WBAntibody00001589 |
| | Microarray_results (24) |
| | Expression_cluster | WBPaper00031040:TGF-beta_adult_downregulated |
| | | WBPaper00032097:CGH-1-associated-mRNA |
| | | WBPaper00037950:CEP-sheath-cells_adult_enriched |
| | | WBPaper00037950:CEP-sheath-cells_adult_SelectivelyEnriched |
| | | WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed |
| | | WBPaper00037950:germline-precursors_embryo_enriched |
| | | WBPaper00037950:germline-precursors_embryo_SelectivelyEnriched |
| | | WBPaper00038061:aldicarb_downregulated |
| | | WBPaper00044426:rotenone_24h_upregulated |
| | | WBPaper00044656:tatn-1(qd182)_downregulated |
| | | WBPaper00044736:flat_dev_expression |
| | | WBPaper00044786:emr-1(gk119)_downregulated |
| | | WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_downregulated |
| | | WBPaper00045050:csr-1(hypomorph)_upregulated |
| | | WBPaper00045050:drh-3 (ne4253)_downregulated |
| | | WBPaper00045420:fertilization_downregulated_transcript |
| | | WBPaper00045521:Oogenic |
| | | WBPaper00045571:germline-ablation_downregulated |
| | | WBPaper00045618:fbf-1_downregulated |
| | | WBPaper00045618:puf-8_downregulated |
| | | WBPaper00045729:gld-2(RNAi)_downregulated |
| | | WBPaper00046499:AMPK_regulated |
| | | WBPaper00048762:FOG-3_associated |
| | | WBPaper00048988:neuron_expressed |
| | | WBPaper00049545:jmjd-3.1(+)_downregulated |
| | | WBPaper00049626:UNC-75_target |
| | | WBPaper00049942:hsf-1(RNAi)_upregulated |
| | | WBPaper00050488:adult_vs_dauer_regulated_N2_20C |
| | | WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C |
| | | WBPaper00050522:mafr-1(tm6082)_downregulated |
| | | WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult |
| | | WBPaper00050859:downregulated_P-granule(-)GFP(-)_vs_control_day2-adult |
| | | WBPaper00050990:body-muscle_expressed |
| | | WBPaper00050990:hypodermis_expressed |
| | | WBPaper00051039:germline_enriched |
| | | WBPaper00052884:emb-4(hc60)_downregulated |
| | | WBPaper00053184:sma-2(rax5)_downregulated |
| | | WBPaper00053184:sma-4(rax3)_downregulated |
| | | WBPaper00053302:alovudine_24h_regulated |
| | | WBPaper00053302:stavudine_24h_regulated |
| | | WBPaper00053302:zidovudine_24h_regulated |
| | | WBPaper00053302:zidovudine_72h_regulated |
| | | WBPaper00053321:PGCs_enriched_NuGen |
| | | WBPaper00053388:dauer_regulated_Cluster2 |
| | | WBPaper00053599:female_vs_male_upregulated |
| | | WBPaper00053606:N2_vs_elt-2(ca15);elt-7(tm840)_upregulated |
| | | WBPaper00053606:N2_vs_elt-2(ca15)_upregulated |
| | | WBPaper00053713:Pheromone-induced_postdauer_vs_control_upregulated |
| | | WBPaper00053713:Starvation-induced_postdauer_vs_control_downregulated |
| | | WBPaper00054191:H3.3(null)_L1_upregulated |
| | | WBPaper00054792:FOG-3_interacting |
| | | WBPaper00055354:eat-2(ad1116)_upregulated |
| | | WBPaper00055354:Rapamycin_upregulated |
| | | WBPaper00055354:Rifampicin_downregulated |
| | | WBPaper00055648:germline_expressed |
| | | WBPaper00055804:FBF-1-FBF-2-associated_oogenic-enriched |
| | | WBPaper00055827:daf-2(e1370)_downregulated |
| | | WBPaper00055862:antimycin_damt-1(gk961032)_regulated |
| | | WBPaper00055971:nhl-2(ok818)_25C_upregulated |
| | | WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047) |
| | | WBPaper00056139:soil-microbiota_downregulated |
| | | WBPaper00056161:hermaphrodite_enriched_siRNA |
| | | WBPaper00056165:MINA-1_interacting_mRNA |
| | | WBPaper00056275:P.aeruginosa_downregulated |
| | | WBPaper00056275:P.aeruginosa_upregulated |
| | | WBPaper00056275:P.aeruginosa_upregulated_atf-7(qd22qd130)_dependent |
| | | WBPaper00056284:ints-5(RNAi)_downregulated |
| | | WBPaper00056290:hsp-6(mg585)_downregulated |
| | | WBPaper00056443:sek-1(km4)_downregulated |
| | | WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated |
| | | WBPaper00057041:spc-1(cas971)_upregulated |
| | | WBPaper00057154:HeatShock_downregulated_mRNA |
| | | WBPaper00057288:Cold_upregulated_transcript |
| | | WBPaper00058598:mex-1(or286)_downregulated |
| | | WBPaper00058598:mex-3(eu149)_downregulated |
| | | WBPaper00058598:sin-3(tm1276)_upregulated |
| | | WBPaper00058691:sin-3(tm1276)_upregulated |
| | | WBPaper00059356:BAZ-2_SET-6_interacting |
| | | WBPaper00059664:srbc-48(ac23)_downregulated |
| | | WBPaper00060445:ikb-1(nr2027)_upregulated_L4 |
| | | WBPaper00060445:nfki-1(cer1)_ikb-1(nr2027)_upregulated_L4 |
| | | WBPaper00060445:nfki-1(cer1)_upregulated_L4 |
| | | WBPaper00060661:sensory-neuron_depleted |
| | | WBPaper00060683:hlh-11(ko1)_downregulated |
| | | WBPaper00060811:L1_vs_adult_downregulated_neural |
| | | WBPaper00060909:atfs-1(cmh15)_upregulated |
| | | WBPaper00061007:HB101_downregulated |
| | | WBPaper00061007:S.aquatilis_downregulated |
| | | WBPaper00061045:Y56A3A.22(cck200)_downregulated |
| | | WBPaper00061106:endu-2(tm4977)_downregulated |
| | | WBPaper00061203:let-418(n3536)_downregulated |
| | | WBPaper00061203:sin-3(tm1276)_downregulated |
| | | WBPaper00061203:spr-1(ok2144)_downregulated |
| | | WBPaper00061274:hypergravity_15xg_upregulated |
| | | WBPaper00061340:ADE |
| | | WBPaper00061340:ant_arc_V |
| | | WBPaper00061340:Germline |
| | | WBPaper00061340:Neuroblast_BAG_SMDVx |
| | | WBPaper00061390:daf-22(ok693)_ascarosides_downregulated |
| | | WBPaper00061478:SUMO-conjugated_protein |
| | | WBPaper00061527:T22D1.5-inx-14 |
| | | WBPaper00061530:nhr-49(e2144)_downregulated |
| | | WBPaper00062159:hda-2(ok1479)_downregulated |
| | | WBPaper00062446:nhr-8(hd117)_downregulated |
| | | WBPaper00064005:starvation_downregulated_aptf-1(gk794)_mRNA |
| | | WBPaper00064005:starvation_downregulated_N2_mRNA |
| | | WBPaper00064071:NHR-49_interacting |
| | | WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141) |
| | | WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20) |
| | | WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141) |
| | | WBPaper00064229:B.thuringiensis-Cry5Ba_downregulated |
| | | WBPaper00064716:paraquat_upregulated |
| | | WBPaper00065373:Cisplatin_upregulated_WT |
| | | WBPaper00065373:sek-1(km4)_upregulated_cisplatin |
| | | WBPaper00065984:pals-17(syb3980)_upregulated |
| | | WBPaper00065993:glp-1(e2141)_downregulated |
| | | WBPaper00066110:Doxorubicin_downregulated_diploid |
| | | WBPaper00066110:tetraploid_vs_diploid_downregulated |
| | | WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14 |
| | | cgc4386_cluster_4_2 |
| | | cgc4489_group_2 |
| | | WBPaper00025032:cluster_101 |
| | | WBPaper00026929:sir-2.1_overexpression_regulated |
| | | WBPaper00031252:AIN-1_IP_enriched |
| | | WBPaper00031252:AIN-2_IP_enriched |
| | | WBPaper00035084:L1_enriched_AIN-2_IP |
| | | WBPaper00035873:dpy-9_regulated |
| | | WBPaper00035873:dpy-10_regulated |
| | | WBPaper00035905:FBF-1_Associated |
| | | WBPaper00036123:Atrazine_regulated |
| | | WBPaper00036130:mir-243_down_regulated |
| | | WBPaper00036286:Pattern_F |
| | | WBPaper00037147:heatshock_upregulated |
| | | WBPaper00037611:GLD-2-associated |
| | | WBPaper00037611:RNP-8-associated |
| | | WBPaper00037901:GLD-1_mRNA_targets |
| | | WBPaper00041606:CE_B.thuringiensis-DB27_regulated |
| | | WBPaper00041606:CE_S.marcescens_regulated |
| | | WBPaper00041606:CE_X.nematophila_regulated |
| | | WBPaper00042331:a-SWCNTs_downregulated |
| | | WBPaper00045263:0.1mM-paraquat_upregulated |
| | | WBPaper00048989:eat-2(ad465)_rapamycin_upregulated |
| | | WBPaper00048989:N2_rapamycin_downregulated |
| | | WBPaper00056330:mrps-5(RNAi)_downregulated |
| | | [cgc5767]:cluster_1 |
| | | [cgc5767]:expression_class_M |
| | | [cgc5767]:expression_class_MD |
| | | [cgc5767]:expression_class_MD_pd(53_min) |
| | | [cgc5767]:expression_class_SM |
| | | [cgc5767]:expression_class_SMD |
| | | [cgc6390]:Cluster_E |
| | | [cgc6390]:oogenesis-enriched |
| | Interaction (309) |
| | WBProcess | WBbiopr:00000017 |
| Map_info | Map | III | Position | 17.7453 | Error | 0.045821 |
| | Well_ordered |
| | Positive | Inside_rearr | ctDf3 |
| | | Positive_clone | pJP604 |
| | | | Y49E10 | Inferred_automatically | From sequence, transcript, pseudogene data |
| | Mapping_data | Multi_point (11) |
| | | Pos_neg_data | 8413 |
| | | | 8414 |
| | | | 8548 |
| | | | 8557 |
| | Landmark_gene |
| Reference (314) |
| Method | Gene |
